Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ass1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ASS1
- Mouse genes Ass1
- Rat genes Ass1
- Zfish genes ass1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ass1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016597	amino acid binding	ASS1	IMP		Human	PMID:7977368
Molecular Function	GO:0004055	argininosuccinate synthase activity	ASS1	IMP		Human	PMID:18473344
Molecular Function	GO:0004055	argininosuccinate synthase activity	ASS1	IMP		Human	PMID:27287393
Molecular Function	GO:0004055	argininosuccinate synthase activity	ASS1	IMP		Human	PMID:28985504
Molecular Function	GO:0004055	argininosuccinate synthase activity	ASS1	IMP		Human	PMID:7977368
Molecular Function	GO:0004055	argininosuccinate synthase activity	ASS1	IMP		Human	PMID:8792870
Molecular Function	GO:0004055	argininosuccinate synthase activity	Ass1	IMP		Rat	PMID:19491403\|RGD:12859071
Molecular Function	GO:0004055	argininosuccinate synthase activity	Ass1	IDA		Rat	PMID:4062872\|RGD:2300098
Molecular Function	GO:0042802	identical protein binding	ASS1	IPI	UniProtKB:P00966	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	ASS1	IPI	UniProtKB:P00966	Human	PMID:21988832
Molecular Function	GO:0042802	identical protein binding	ASS1	IPI	UniProtKB:P00966	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ASS1	IPI	UniProtKB:P10398	Human	PMID:12620389
Molecular Function	GO:0005515	protein binding	ASS1	IPI	UniProtKB:Q9HBL8	Human	PMID:17496144
Molecular Function	GO:0005515	protein binding	ASS1	IPI	UniProtKB:Q9NVM4	Human	PMID:28587924
Molecular Function	GO:0005515	protein binding	ASS1	IPI	UniProtKB:O15516	Human	PMID:28985504
Molecular Function	GO:0005515	protein binding	Ass1	IPI	UniProtKB:O08785	Mouse	MGI:MGI:6103563\|PMID:28985504
Molecular Function	GO:0005515	protein binding	Ass1	IPI	UniProtKB:P70313\|UniProtKB:Q09143\|UniProtKB:Q91YI0	Mouse	MGI:MGI:5305859\|PMID:22081021
Molecular Function	GO:0003723	RNA binding	ASS1	HDA		Human	PMID:22658674
Molecular Function	GO:0015643	toxic substance binding	Ass1	IPI	PubChem_Compound:3431	Rat	PMID:11083085\|RGD:1599312
Cellular Component	GO:0070852	cell body fiber	Ass1	IDA		Rat	PMID:12445581\|RGD:4139895
Cellular Component	GO:0005737	cytoplasm	Ass1	IDA		Rat	PMID:8867809\|RGD:1599270
Cellular Component	GO:0005829	cytosol	ASS1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	ASS1	IDA		Human	PMID:28985504
Cellular Component	GO:0005783	endoplasmic reticulum	Ass1	IDA		Rat	PMID:8867809\|RGD:1599270
Cellular Component	GO:0070062	extracellular exosome	ASS1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ASS1	HDA		Human	PMID:23533145
Cellular Component	GO:0005764	lysosome	Ass1	IDA		Rat	PMID:10469394\|RGD:4142786
Cellular Component	GO:0005741	mitochondrial outer membrane	Ass1	IDA		Rat	PMID:8867809\|RGD:1599270
Cellular Component	GO:0005739	mitochondrion	Ass1	IDA		Mouse	PMID:14701727
Cellular Component	GO:0043209	myelin sheath	Ass1	HDA		Mouse	MGI:MGI:3834050\|PMID:17634366
Cellular Component	GO:0043005	neuron projection	Ass1	IDA		Rat	PMID:17198704\|RGD:1599263
Cellular Component	GO:0043025	neuronal cell body	Ass1	IDA		Rat	PMID:12445581\|RGD:4139895
Cellular Component	GO:0005654	nucleoplasm	ASS1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Ass1	IDA		Rat	PMID:17900569\|RGD:4110827
Cellular Component	GO:0043204	perikaryon	Ass1	IDA		Rat	PMID:17900569\|RGD:4110827
Biological Process	GO:0006953	acute-phase response	Ass1	IEP		Rat	PMID:15698416\|RGD:1599305
Biological Process	GO:0007568	aging	Ass1	IEP		Rat	PMID:12044965\|RGD:4140929
Biological Process	GO:0006526	arginine biosynthetic process	ASS1	IMP		Human	PMID:18473344
Biological Process	GO:0006526	arginine biosynthetic process	ASS1	IMP		Human	PMID:27287393
Biological Process	GO:0006526	arginine biosynthetic process	ASS1	IMP		Human	PMID:8792870
Biological Process	GO:0006526	arginine biosynthetic process	Ass1	IDA		Rat	PMID:12470967\|RGD:631755
Biological Process	GO:0006526	arginine biosynthetic process	Ass1	IMP		Rat	PMID:19491403\|RGD:12859071
Biological Process	GO:0000053	argininosuccinate metabolic process	ASS1	IMP		Human	PMID:7977368
Biological Process	GO:0000053	argininosuccinate metabolic process	Ass1	IDA		Rat	PMID:4062872\|RGD:2300098
Biological Process	GO:0006531	aspartate metabolic process	ASS1	IMP		Human	PMID:7977368
Biological Process	GO:0071418	cellular response to amine stimulus	Ass1	IEP		Rat	PMID:18457831\|RGD:4140461
Biological Process	GO:0071230	cellular response to amino acid stimulus	Ass1	IEP		Rat	PMID:9893939\|RGD:4142787
Biological Process	GO:0071242	cellular response to ammonium ion	Ass1	IEP		Rat	PMID:10353334\|RGD:1599267
Biological Process	GO:0071320	cellular response to cAMP	Ass1	IEP		Rat	PMID:8923475\|RGD:1599316
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	Ass1	IEP		Rat	PMID:9395312\|RGD:4139912
Biological Process	GO:0071377	cellular response to glucagon stimulus	Ass1	IEP		Rat	PMID:9395312\|RGD:4139912
Biological Process	GO:0071499	cellular response to laminar fluid shear stress	ASS1	IMP		Human	PMID:21106532
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Ass1	IEP		Rat	PMID:9879717\|RGD:4139906
Biological Process	GO:0071400	cellular response to oleic acid	Ass1	IEP		Rat	PMID:8985169\|RGD:2303518
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Ass1	IEP		Rat	PMID:11072090\|RGD:4139899
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Ass1	IEP		Rat	PMID:12589771\|RGD:1599307
Biological Process	GO:0071346	cellular response to type II interferon	Ass1	IEP		Rat	PMID:11072090\|RGD:4139899
Biological Process	GO:0071346	cellular response to type II interferon	Ass1	IEP		Rat	PMID:12589771\|RGD:1599307
Biological Process	GO:0007623	circadian rhythm	ASS1	IDA		Human	PMID:28985504
Biological Process	GO:0007623	circadian rhythm	Ass1	IDA		Mouse	MGI:MGI:6103563\|PMID:28985504
Biological Process	GO:0000052	citrulline metabolic process	ASS1	IMP		Human	PMID:7977368
Biological Process	GO:0060539	diaphragm development	Ass1	IEP		Rat	PMID:9618389\|RGD:4139909
Biological Process	GO:0001822	kidney development	Ass1	IEP		Rat	PMID:10473900\|RGD:1599266
Biological Process	GO:0001889	liver development	Ass1	IEP		Rat	PMID:10473900\|RGD:1599266
Biological Process	GO:0001889	liver development	Ass1	IEP		Rat	PMID:9395312\|RGD:4139912
Biological Process	GO:0007494	midgut development	Ass1	IEP		Rat	PMID:9544996\|RGD:4139911
Biological Process	GO:1903038	negative regulation of leukocyte cell-cell adhesion	ASS1	IMP		Human	PMID:21106532
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	ASS1	IMP		Human	PMID:21106532
Biological Process	GO:0014075	response to amine	Ass1	IEP		Rat	PMID:16168957\|RGD:4110830
Biological Process	GO:0043200	response to amino acid	Ass1	IEP		Rat	PMID:17938381\|RGD:4140474
Biological Process	GO:0032355	response to estradiol	Ass1	IEP		Rat	PMID:16339744\|RGD:1599058
Biological Process	GO:0070542	response to fatty acid	Ass1	IEP		Rat	PMID:19651254\|RGD:4140454
Biological Process	GO:0051384	response to glucocorticoid	Ass1	IDA		Rat	PMID:8923475\|RGD:1599316
Biological Process	GO:0060416	response to growth hormone	Ass1	IEP		Rat	PMID:9688877\|RGD:1599313
Biological Process	GO:0032496	response to lipopolysaccharide	Ass1	IEP		Rat	PMID:12589771\|RGD:1599307
Biological Process	GO:0010046	response to mycotoxin	Ass1	IDA		Rat	PMID:11083085\|RGD:1599312
Biological Process	GO:0007584	response to nutrient	Ass1	IEP		Rat	PMID:15257170\|RGD:1599306
Biological Process	GO:0043434	response to peptide hormone	Ass1	IEP		Rat	PMID:9688877\|RGD:1599313
Biological Process	GO:0048545	response to steroid hormone	Ass1	IEP		Rat	PMID:9688877\|RGD:1599313
Biological Process	GO:0009636	response to toxic substance	Ass1	IEP		Rat	PMID:20452409\|RGD:4110826
Biological Process	GO:0009410	response to xenobiotic stimulus	Ass1	IEP		Rat	PMID:9252090\|RGD:1599314
Biological Process	GO:0010043	response to zinc ion	Ass1	IDA		Rat	PMID:11686784\|RGD:1599309
Biological Process	GO:0000050	urea cycle	ASS1	IMP		Human	PMID:18473344
Biological Process	GO:0000050	urea cycle	ASS1	IMP		Human	PMID:27287393
Biological Process	GO:0000050	urea cycle	ASS1	IMP		Human	PMID:7977368
Biological Process	GO:0000050	urea cycle	ASS1	IMP		Human	PMID:8792870
Biological Process	GO:0000050	urea cycle	Ass1	IMP		Rat	PMID:19491403\|RGD:12859071
Biological Process	GO:0000050	urea cycle	Ass1	IDA		Rat	PMID:4062872\|RGD:2300098

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.