Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ASXL1
  • Mouse genes Asxl1
  • Rat genes Asxl1
  • Zfish genes asxl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Asxl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	Asxl1	IDA		Mouse	MGI:MGI:3688807|PMID:16606617
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	Asxl1	IDA		Mouse	MGI:MGI:5318011|PMID:21047783
Molecular Function	GO:0005515	protein binding	ASXL1	IPI	UniProtKB:P03372	Human	PMID:16606617
Molecular Function	GO:0005515	protein binding	ASXL1	IPI	UniProtKB:P28700	Human	PMID:16606617
Molecular Function	GO:0005515	protein binding	ASXL1	IPI	UniProtKB:P68306	Human	PMID:16606617
Molecular Function	GO:0005515	protein binding	ASXL1	IPI	UniProtKB:P31749	Human	PMID:18624398
Molecular Function	GO:0005515	protein binding	ASXL1	IPI	UniProtKB:Q92560	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	ASXL1	IPI	UniProtKB:Q92560	Human	PMID:20436459
Molecular Function	GO:0005515	protein binding	ASXL1	IPI	UniProtKB:O75530	Human	PMID:22897849
Molecular Function	GO:0005515	protein binding	ASXL1	IPI	UniProtKB:Q15910	Human	PMID:22897849
Molecular Function	GO:0005515	protein binding	ASXL1	IPI	UniProtKB:Q92560	Human	PMID:22897849
Molecular Function	GO:0005515	protein binding	ASXL1	IPI	UniProtKB:Q92560	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	ASXL1	IPI	UniProtKB:A6NEM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Asxl1	IPI	UniProtKB:P03372|UniProtKB:P04150|UniProtKB:P10276|UniProtKB:P28700|UniProtKB:Q15788	Mouse	MGI:MGI:3688807|PMID:16606617
Molecular Function	GO:0005515	protein binding	Asxl1	IPI	UniProtKB:Q99PU7	Mouse	PMID:22878500
Molecular Function	GO:0005515	protein binding	Asxl1	IPI	PR:Q61188	Mouse	PMID:24216483
Molecular Function	GO:0003713	transcription coactivator activity	Asxl1	IDA		Mouse	MGI:MGI:3688807|PMID:16606617
Cellular Component	GO:0005634	nucleus	Asxl1	IDA		Mouse	PMID:24216483
Cellular Component	GO:0035517	PR-DUB complex	ASXL1	IPI		Human	PMID:20436459
Cellular Component	GO:0035517	PR-DUB complex	ASXL1	IDA		Human	PMID:20436459
Biological Process	GO:0009887	animal organ morphogenesis	Asxl1	IMP	MGI:MGI:4418244	Mouse	PMID:19861679
Biological Process	GO:0060348	bone development	Asxl1	IMP		Mouse	PMID:22876197
Biological Process	GO:0048539	bone marrow development	Asxl1	IMP	MGI:MGI:4418244	Mouse	PMID:19861679
Biological Process	GO:0000902	cell morphogenesis	Asxl1	IMP	MGI:MGI:4418244	Mouse	PMID:19861679
Biological Process	GO:0003007	heart morphogenesis	Asxl1	IMP	MGI:MGI:4431878	Mouse	PMID:24860998
Biological Process	GO:0048534	hematopoietic or lymphoid organ development	Asxl1	IMP	MGI:MGI:4418244	Mouse	PMID:19861679
Biological Process	GO:0030097	hemopoiesis	Asxl1	IMP	MGI:MGI:4418244	Mouse	PMID:19861679
Biological Process	GO:0048872	homeostasis of number of cells	Asxl1	IMP	MGI:MGI:4418244	Mouse	PMID:19861679
Biological Process	GO:0060430	lung saccule development	Asxl1	IMP	MGI:MGI:4431878	Mouse	PMID:24860998
Biological Process	GO:0061516	monocyte proliferation	asxl1	IMP	ZFIN:ZDB-GENO-221129-4	Zfish	PMID:33483612
Biological Process	GO:0035522	monoubiquitinated histone H2A deubiquitination	ASXL1	IDA		Human	PMID:20436459
Biological Process	GO:0045599	negative regulation of fat cell differentiation	Asxl1	IDA		Mouse	MGI:MGI:5318011|PMID:21047783
Biological Process	GO:0010888	negative regulation of lipid storage	Asxl1	IMP		Rat	PMID:24321552|RGD:15023475
Biological Process	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway	Asxl1	IDA		Mouse	MGI:MGI:5318011|PMID:21047783
Biological Process	GO:0072015	podocyte development	Asxl1	IMP		Mouse	MGI:MGI:5751943|PMID:26385183
Biological Process	GO:0048386	positive regulation of retinoic acid receptor signaling pathway	Asxl1	IDA		Mouse	MGI:MGI:3688807|PMID:16606617
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Asxl1	IDA		Mouse	MGI:MGI:3688807|PMID:16606617
Biological Process	GO:0035564	regulation of kidney size	Asxl1	IMP		Mouse	MGI:MGI:5751943|PMID:26385183
Biological Process	GO:0045658	regulation of neutrophil differentiation	asxl1	IMP	ZFIN:ZDB-GENO-221129-4	Zfish	PMID:33483612
Biological Process	GO:0032526	response to retinoic acid	Asxl1	IDA		Mouse	MGI:MGI:3688807|PMID:16606617
Biological Process	GO:0048538	thymus development	Asxl1	IMP	MGI:MGI:4418244	Mouse	PMID:19861679

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern