Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATAD5
  • Mouse genes Atad5
  • Rat genes Atad5
  • Zfish genes atad5a,atad5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atad5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0061860	DNA clamp unloader activity	ATAD5	IMP		Human	PMID:23277426
Molecular Function	GO:0005515	protein binding	ATAD5	IPI	UniProtKB:O60885	Human	PMID:21555454
Molecular Function	GO:0005515	protein binding	ATAD5	IPI	UniProtKB:P35249	Human	PMID:23277426
Molecular Function	GO:0005515	protein binding	Atad5	IPI	PR:Q9Z0F6	Mouse	PMID:15983387
Molecular Function	GO:0005515	protein binding	Atad5	IPI	PR:P13405	Mouse	PMID:15983387
Cellular Component	GO:0031391	Elg1 RFC-like complex	ATAD5	IDA		Human	PMID:23277426
Cellular Component	GO:0005634	nucleus	Atad5	IDA		Mouse	PMID:15983387
Biological Process	GO:0008283	cell population proliferation	Atad5	IMP	MGI:4127920	Mouse	PMID:25404367
Biological Process	GO:0006974	DNA damage response	Atad5	IMP		Mouse	PMID:15983387
Biological Process	GO:0002377	immunoglobulin production	Atad5	IMP	MGI:MGI:4127920	Mouse	PMID:25404367
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	Atad5	IGI	MGI:MGI:1328356	Mouse	PMID:15983387
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	Atad5	IGI	MGI:MGI:88138	Mouse	PMID:15983387
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Atad5	IGI	MGI:MGI:1336991	Mouse	PMID:15983387
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Atad5	IGI	MGI:MGI:98834	Mouse	PMID:15983387
Biological Process	GO:0045190	isotype switching	Atad5	IMP	MGI:4127920	Mouse	PMID:25404367
Biological Process	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	Atad5	IMP		Mouse	PMID:15983387
Biological Process	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Atad5	IMP		Mouse	MGI:MGI:3584078|PMID:15983387
Biological Process	GO:0033260	nuclear DNA replication	Atad5	IMP	MGI:4127920	Mouse	PMID:25404367
Biological Process	GO:0090305	nucleic acid phosphodiester bond hydrolysis	Atad5	IMP	MGI:4127920	Mouse	PMID:25404367
Biological Process	GO:0030890	positive regulation of B cell proliferation	Atad5	IMP	MGI:MGI:4127920	Mouse	PMID:25404367
Biological Process	GO:1902751	positive regulation of cell cycle G2/M phase transition	ATAD5	IMP		Human	PMID:23277426
Biological Process	GO:0045740	positive regulation of DNA replication	ATAD5	IMP		Human	PMID:23277426
Biological Process	GO:0048304	positive regulation of isotype switching to IgG isotypes	Atad5	IMP	MGI:MGI:4127920	Mouse	PMID:25404367
Biological Process	GO:1901990	regulation of mitotic cell cycle phase transition	Atad5	IMP	MGI:MGI:4127920	Mouse	PMID:25404367
Biological Process	GO:0042770	signal transduction in response to DNA damage	Atad5	IMP		Mouse	PMID:15983387

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern