Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATF5
  • Mouse genes Atf5
  • Rat genes Atf5
  • Zfish genes atf5a,atf5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atf5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	ATF5	IDA		Human	PMID:21212266
Molecular Function	GO:0003682	chromatin binding	Atf5	IDA		Mouse	MGI:MGI:5688824|PMID:24216764
Molecular Function	GO:0003682	chromatin binding	Atf5	IDA		Rat	PMID:21212266|RGD:10400862
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ATF5	IDA		Human	PMID:16300731
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ATF5	IDA		Human	PMID:20654631
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Atf5	IDA		Rat	PMID:19531563|RGD:10400874
Molecular Function	GO:0031072	heat shock protein binding	Atf5	IPI	RGD:628878	Rat	PMID:21521685|RGD:5687155
Molecular Function	GO:0019900	kinase binding	ATF5	IPI	UniProtKB:Q9UBE8	Human	PMID:25512613
Molecular Function	GO:0005515	protein binding	ATF5	IPI	UniProtKB:P49427	Human	PMID:10373550
Molecular Function	GO:0005515	protein binding	ATF5	IPI	UniProtKB:Q9NRI5	Human	PMID:12812986
Molecular Function	GO:0005515	protein binding	ATF5	IPI	UniProtKB:P49715	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	ATF5	IPI	UniProtKB:P53567	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	ATF5	IPI	UniProtKB:P53567	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	ATF5	IPI	UniProtKB:P06748|UniProtKB:P0DMV8|UniProtKB:P0DMV9	Human	PMID:22528486
Molecular Function	GO:0005515	protein binding	ATF5	IPI	UniProtKB:P49715	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	ATF5	IPI	UniProtKB:P53567	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	ATF5	IPI	UniProtKB:P48725|UniProtKB:Q9BSJ2|UniProtKB:Q9UGJ1	Human	PMID:26213385
Molecular Function	GO:0005515	protein binding	ATF5	IPI	UniProtKB:P02766	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATF5	IPI	UniProtKB:P53567	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATF5	IPI	UniProtKB:Q13227	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATF5	IPI	UniProtKB:Q14232	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATF5	IPI	UniProtKB:Q16204	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATF5	IPI	UniProtKB:Q14145	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Atf5	IPI	UniProtKB:B2RWS6,UniProtKB:P28033	Mouse	MGI:MGI:5688824|PMID:24216764
Molecular Function	GO:0005515	protein binding	Atf5	IPI	PR:Q3TCJ1	Mouse	PMID:22974638
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ATF5	IMP		Human	PMID:15890932
Molecular Function	GO:0043565	sequence-specific DNA binding	Atf5	IDA		Mouse	MGI:MGI:5688824|PMID:24216764
Molecular Function	GO:0043565	sequence-specific DNA binding	Atf5	IDA		Rat	PMID:19531563|RGD:10400874
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Atf5	IDA		Mouse	MGI:MGI:5688824|PMID:24216764
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Atf5	IDA		Rat	PMID:19531563|RGD:10400874
Molecular Function	GO:0015631	tubulin binding	ATF5	IDA		Human	PMID:26213385
Cellular Component	GO:0005813	centrosome	ATF5	IDA		Human	PMID:26213385
Cellular Component	GO:0005829	cytosol	ATF5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ATF5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ATF5	IDA		Human	PMID:22528486
Cellular Component	GO:0005634	nucleus	Atf5	IDA		Mouse	MGI:MGI:5689090|PMID:22095825
Cellular Component	GO:0005634	nucleus	Atf5	IDA		Rat	PMID:15829641|RGD:2302988
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ATF5	IPI		Human	PMID:20102225
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ATF5	IPI		Human	PMID:23661758
Cellular Component	GO:0005667	transcription regulator complex	Atf5	IDA		Mouse	PMID:10777215
Biological Process	GO:0021930	cerebellar granule cell precursor proliferation	Atf5	IMP		Mouse	MGI:MGI:5689090|PMID:22095825
Biological Process	GO:0007623	circadian rhythm	Atf5	IEP		Mouse	MGI:MGI:5292598|PMID:21768648
Biological Process	GO:0045444	fat cell differentiation	ATF5	IMP		Human	PMID:24216764
Biological Process	GO:0045444	fat cell differentiation	Atf5	IMP		Mouse	MGI:MGI:5688824|PMID:24216764
Biological Process	GO:0035264	multicellular organism growth	Atf5	IMP	MGI:MGI:5467393	Mouse	PMID:23090999
Biological Process	GO:0043066	negative regulation of apoptotic process	ATF5	IMP		Human	PMID:21212266
Biological Process	GO:0043066	negative regulation of apoptotic process	Atf5	IDA		Mouse	PMID:12130540
Biological Process	GO:0043066	negative regulation of apoptotic process	Atf5	IMP		Rat	PMID:21212266|RGD:10400862
Biological Process	GO:0048712	negative regulation of astrocyte differentiation	Atf5	IMP		Rat	PMID:15829641|RGD:2302988
Biological Process	GO:1902750	negative regulation of cell cycle G2/M phase transition	ATF5	IDA		Human	PMID:22528486
Biological Process	GO:0008285	negative regulation of cell population proliferation	ATF5	IDA		Human	PMID:22528486
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ATF5	IDA		Human	PMID:22528486
Biological Process	GO:0050768	negative regulation of neurogenesis	Atf5	IDA		Rat	PMID:12805299|RGD:634608
Biological Process	GO:0021891	olfactory bulb interneuron development	Atf5	IMP	MGI:MGI:5467393	Mouse	PMID:23090999
Biological Process	GO:0021889	olfactory bulb interneuron differentiation	Atf5	IMP	MGI:MGI:5467393	Mouse	PMID:23090999
Biological Process	GO:0021988	olfactory lobe development	Atf5	IMP	MGI:MGI:5467393	Mouse	PMID:23090999
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ATF5	IDA		Human	PMID:21212266
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ATF5	IDA		Human	PMID:25512613
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Atf5	IDA		Rat	PMID:19531563|RGD:10400874
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Atf5	IDA		Rat	PMID:21212266|RGD:10400862
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ATF5	IDA		Human	PMID:16300731
Biological Process	GO:0009791	post-embryonic development	Atf5	IMP	MGI:MGI:5467393	Mouse	PMID:23090999
Biological Process	GO:0046605	regulation of centrosome cycle	ATF5	IDA		Human	PMID:26213385
Biological Process	GO:0006355	regulation of DNA-templated transcription	ATF5	IDA		Human	PMID:20654631
Biological Process	GO:0010468	regulation of gene expression	Atf5	IMP	MGI:MGI:5467393	Mouse	PMID:23090999
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Atf5	IDA		Mouse	PMID:10777215

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern