Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATG16L1
  • Mouse genes Atg16l1
  • Rat genes Atg16l1
  • Zfish genes atg16l1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atg16l1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051020	GTPase binding	ATG16L1	IPI	UniProtKB:A1A4Y4	Human	PMID:25891078
Molecular Function	GO:0042802	identical protein binding	ATG16L1	IPI	UniProtKB:Q676U5	Human	PMID:20562859
Molecular Function	GO:0042802	identical protein binding	ATG16L1	IPI	UniProtKB:Q676U5	Human	PMID:23392225
Molecular Function	GO:0042802	identical protein binding	Atg16l1	IPI	UniProtKB:Q8C0J2-2	Mouse	MGI:MGI:2661260|PMID:12665549
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:P60520	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:Q8TDY2	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:Q9BXW4	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:Q9GZQ8	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:Q9H1Y0	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:Q9H1Y0	Human	PMID:23202584
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:Q8TDY2	Human	PMID:23262492
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:O60603	Human	PMID:23376921
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:Q9BXS4	Human	PMID:23376921
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:Q9HC29	Human	PMID:23376921
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:Q8TDY2	Human	PMID:23392225
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:Q9H1Y0	Human	PMID:23392225
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:O15553	Human	PMID:26347139
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:Q5MNZ9	Human	PMID:28561066
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:Q9Y4P8	Human	PMID:28561066
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:Q8TDY2	Human	PMID:28890335
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:Q14088	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:Q9H082	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATG16L1	IPI	UniProtKB:Q8C624	Human	PMID:33087875
Molecular Function	GO:0005515	protein binding	Atg16l1	IPI	UniProtKB:Q8C624	Mouse	MGI:MGI:6763857|PMID:33087875
Molecular Function	GO:0005515	protein binding	Atg16l1	IPI	UniProtKB:O35963	Mouse	MGI:MGI:5447922|PMID:18448665
Molecular Function	GO:0005515	protein binding	Atg16l1	IPI	UniProtKB:P23242	Mouse	MGI:MGI:5915435|PMID:24705551
Molecular Function	GO:0005515	protein binding	Atg16l1	IPI	UniProtKB:Q9ESK9|UniProtKB:Q8TDY2|UniProtKB:Q9ESK9|UniProtKB:Q9H1Y0	Mouse	MGI:MGI:5916255|PMID:23262492
Molecular Function	GO:0005515	protein binding	Atg16l1	IPI	UniProtKB:Q61025	Mouse	MGI:MGI:5527012|PMID:24089209
Molecular Function	GO:0005515	protein binding	Atg16l1	IPI	UniProtKB:Q9ESK9	Mouse	MGI:MGI:5508687|PMID:23392225
Molecular Function	GO:0005515	protein binding	Atg16l1	IPI	PR:Q80W47	Mouse	PMID:24954904
Molecular Function	GO:0005515	protein binding	Atg16l1	IPI	PR:Q9ESK9	Mouse	PMID:24954904
Molecular Function	GO:0005515	protein binding	Atg16l1	IPI	PR:Q8C0J2	Mouse	PMID:12665549
Molecular Function	GO:0005515	protein binding	Atg16l1	IPI	PR:Q99J83	Mouse	PMID:12665549
Cellular Component	GO:0034274	Atg12-Atg5-Atg16 complex	ATG16L1	IPI		Human	PMID:23202584
Cellular Component	GO:0034274	Atg12-Atg5-Atg16 complex	ATG16L1	IDA		Human	PMID:29317426
Cellular Component	GO:0034274	Atg12-Atg5-Atg16 complex	ATG16L1	IDA		Human	PMID:33586810
Cellular Component	GO:0034274	Atg12-Atg5-Atg16 complex	Atg16l1	IDA		Mouse	MGI:MGI:2661260|PMID:12665549
Cellular Component	GO:0005776	autophagosome	Atg16l1	IDA		Mouse	PMID:12665549
Cellular Component	GO:0000421	autophagosome membrane	ATG16L1	IDA		Human	PMID:29317426
Cellular Component	GO:0000421	autophagosome membrane	Atg16l1	IDA		Mouse	PMID:21220506
Cellular Component	GO:0005930	axoneme	Atg16l1	IDA		Mouse	MGI:MGI:5527012|PMID:24089209
Cellular Component	GO:0005737	cytoplasm	Atg16l1	IDA		Mouse	MGI:MGI:6763857|PMID:33087875
Cellular Component	GO:0036020	endolysosome membrane	ATG16L1	IDA		Human	PMID:29317426
Cellular Component	GO:0034045	phagophore assembly site membrane	Atg16l1	IDA		Mouse	MGI:MGI:2661260|PMID:12665549
Cellular Component	GO:0097225	sperm midpiece	Atg16l1	IDA		Mouse	MGI:MGI:6763857|PMID:33087875
Cellular Component	GO:0120095	vacuole-isolation membrane contact site	ATG16L1	IDA		Human	PMID:28890335
Biological Process	GO:0000045	autophagosome assembly	Atg16l1	IMP		Mouse	MGI:MGI:2137756|PMID:11266458
Biological Process	GO:0006501	C-terminal protein lipidation	ATG16L1	IDA		Human	PMID:33586810
Biological Process	GO:0022038	corpus callosum development	Atg16l1	IMP	MGI:4432181	Mouse	PMID:29078390
Biological Process	GO:0051607	defense response to virus	Atg16l1	IMP		Mouse	MGI:MGI:6709815|PMID:33586810
Biological Process	GO:0021766	hippocampus development	Atg16l1	IMP	MGI:4432181	Mouse	PMID:29078390
Biological Process	GO:0016237	lysosomal microautophagy	ATG16L1	IDA		Human	PMID:29317426
Biological Process	GO:0016237	lysosomal microautophagy	ATG16L1	IDA		Human	PMID:33586810
Biological Process	GO:0016237	lysosomal microautophagy	Atg16l1	IMP		Mouse	MGI:MGI:6709815|PMID:33586810
Biological Process	GO:0016236	macroautophagy	ATG16L1	IDA		Human	PMID:29317426
Biological Process	GO:0016236	macroautophagy	ATG16L1	IDA		Human	PMID:33586810
Biological Process	GO:0016236	macroautophagy	Atg16l1	IMP		Mouse	MGI:MGI:2137756|PMID:11266458
Biological Process	GO:0039689	negative stranded viral RNA replication	Atg16l1	IMP		Mouse	PMID:24550300
Biological Process	GO:0010508	positive regulation of autophagy	Atg16l1	IDA		Mouse	MGI:MGI:6271293|PMID:30208760
Biological Process	GO:0006497	protein lipidation	ATG16L1	IDA		Human	PMID:23202584
Biological Process	GO:0061739	protein lipidation involved in autophagosome assembly	Atg16l1	IDA		Mouse	PMID:24954904
Biological Process	GO:0034497	protein localization to phagophore assembly site	Atg16l1	IPI	PR:Q80W47	Mouse	PMID:24954904
Biological Process	GO:0098792	xenophagy	Atg16l1	IPI	PR:Q80W47	Mouse	PMID:24954904

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern