Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATG16L2
  • Mouse genes Atg16l2
  • Rat genes Atg16l2
  • Zfish genes atg16l2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atg16l2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Atg16l2	IPI	UniProtKB:Q99J83	Mouse	MGI:MGI:6436405|PMID:22082872
Cellular Component	GO:0034274	Atg12-Atg5-Atg16 complex	ATG16L2	IPI		Human	PMID:23202584
Cellular Component	GO:0034274	Atg12-Atg5-Atg16 complex	Atg16l2	IDA		Mouse	MGI:MGI:2661260|PMID:12665549
Cellular Component	GO:0005829	cytosol	Atg16l2	IDA		Mouse	MGI:MGI:6436405|PMID:22082872
Cellular Component	GO:0005654	nucleoplasm	ATG16L2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0034045	phagophore assembly site membrane	Atg16l2	IDA		Mouse	MGI:MGI:2661260|PMID:12665549
Biological Process	GO:0000045	autophagosome assembly	Atg16l2	IMP		Mouse	MGI:MGI:2137756|PMID:11266458
Biological Process	GO:0016236	macroautophagy	Atg16l2	IMP		Mouse	MGI:MGI:2137756|PMID:11266458
Biological Process	GO:0039689	negative stranded viral RNA replication	Atg16l2	IMP		Mouse	PMID:24550300
Biological Process	GO:0006497	protein lipidation	ATG16L2	IDA		Human	PMID:23202584

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern