Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATG3
  • Mouse genes Atg3
  • Rat genes Atg3
  • Zfish genes atg3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atg3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019777	Atg12 transferase activity	Atg3	IDA		Mouse	MGI:MGI:4835103|PMID:20723759
Molecular Function	GO:0019776	Atg8 ligase activity	Atg3	IMP		Mouse	MGI:MGI:4835103|PMID:20723759
Molecular Function	GO:0019899	enzyme binding	ATG3	IPI	UniProtKB:O95352	Human	PMID:11825910
Molecular Function	GO:0005515	protein binding	ATG3	IPI	UniProtKB:O94817	Human	PMID:11825910
Molecular Function	GO:0005515	protein binding	ATG3	IPI	UniProtKB:P60520	Human	PMID:11825910
Molecular Function	GO:0005515	protein binding	ATG3	IPI	UniProtKB:Q9GZQ8	Human	PMID:15355958
Molecular Function	GO:0005515	protein binding	ATG3	IPI	UniProtKB:O95166	Human	PMID:16303767
Molecular Function	GO:0005515	protein binding	ATG3	IPI	UniProtKB:P60520	Human	PMID:16303767
Molecular Function	GO:0005515	protein binding	ATG3	IPI	UniProtKB:Q9GZQ8	Human	PMID:16303767
Molecular Function	GO:0005515	protein binding	ATG3	IPI	UniProtKB:Q9GZQ8	Human	PMID:18083104
Molecular Function	GO:0005515	protein binding	ATG3	IPI	UniProtKB:O94817	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG3	IPI	UniProtKB:O95166	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG3	IPI	UniProtKB:P60520	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG3	IPI	UniProtKB:Q7Z6L1	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG3	IPI	UniProtKB:Q9GZQ8	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG3	IPI	UniProtKB:Q9H0R8	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG3	IPI	UniProtKB:O94817	Human	PMID:23202584
Molecular Function	GO:0005515	protein binding	ATG3	IPI	UniProtKB:O94817	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATG3	IPI	UniProtKB:Q70IA6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATG3	IPI	UniProtKB:P62879	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Atg3	IPI	UniProtKB:Q9CQY1	Mouse	MGI:MGI:5914142|PMID:25686249
Molecular Function	GO:0005515	protein binding	Atg3	IPI	UniProtKB:Q9CQY1	Mouse	MGI:MGI:4835103|PMID:20723759
Molecular Function	GO:0019787	ubiquitin-like protein transferase activity	ATG3	IDA		Human	PMID:11825910
Cellular Component	GO:0005737	cytoplasm	ATG3	IDA		Human	PMID:11825910
Cellular Component	GO:0005829	cytosol	ATG3	IDA		Human	PMID:11825910
Cellular Component	GO:0005829	cytosol	Atg3	IDA		Rat	PMID:17110912|RGD:1643237
Biological Process	GO:0000045	autophagosome assembly	Atg3	IMP		Mouse	MGI:MGI:4835103|PMID:20723759
Biological Process	GO:0000045	autophagosome assembly	Atg3	IMP		Mouse	PMID:21220506
Biological Process	GO:0006914	autophagy	Atg3	IEP		Rat	PMID:17110912|RGD:1643237
Biological Process	GO:0016236	macroautophagy	Atg3	IMP		Mouse	PMID:24035364
Biological Process	GO:0043653	mitochondrial fragmentation involved in apoptotic process	Atg3	IMP		Mouse	MGI:MGI:4835103|PMID:20723759
Biological Process	GO:0050765	negative regulation of phagocytosis	Atg3	IMP		Mouse	PMID:24035364
Biological Process	GO:0016567	protein ubiquitination	ATG3	IDA		Human	PMID:11825910
Biological Process	GO:1902017	regulation of cilium assembly	Atg3	IMP		Mouse	MGI:MGI:5527013|PMID:24089205

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern