Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATG4D
  • Mouse genes Atg4d
  • Rat genes Atg4d
  • Zfish genes atg4da,atg4db
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atg4d

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008234	cysteine-type peptidase activity	ATG4D	IDA		Human	PMID:21177865
Molecular Function	GO:0008234	cysteine-type peptidase activity	ATG4D	IDA		Human	PMID:30661429
Cellular Component	GO:0005739	mitochondrion	ATG4D	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ATG4D	IDA		Human	GO_REF:0000052
Biological Process	GO:0006914	autophagy	ATG4D	IDA		Human	PMID:30661429
Biological Process	GO:0098749	cerebellar neuron development	atg4da	IMP	ZFIN:ZDB-MRPHLNO-150604-2	Zfish	PMID:25875846
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	atg4da	IMP	ZFIN:ZDB-MRPHLNO-150604-2	Zfish	PMID:25875846
Biological Process	GO:0000423	mitophagy	ATG4D	IMP		Human	PMID:33773106
Biological Process	GO:0051697	protein delipidation	ATG4D	IDA		Human	PMID:29458288
Biological Process	GO:0051697	protein delipidation	Atg4d	IMP		Mouse	MGI:MGI:6764118|PMID:33795848
Biological Process	GO:0034497	protein localization to phagophore assembly site	ATG4D	IMP		Human	PMID:33773106
Biological Process	GO:0006508	proteolysis	ATG4D	IDA		Human	PMID:21177865

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern