Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATOX1
  • Mouse genes Atox1
  • Rat genes Atox1
  • Zfish genes atox1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atox1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	Atox1	IPI	RGD:2179	Rat	PMID:23349186|RGD:11341699
Molecular Function	GO:0016531	copper chaperone activity	ATOX1	IDA		Human	PMID:12029094
Molecular Function	GO:0005507	copper ion binding	ATOX1	IDA		Human	PMID:12029094
Molecular Function	GO:0032767	copper-dependent protein binding	ATOX1	IPI	UniProtKB:Q04656	Human	PMID:10497213
Molecular Function	GO:0032767	copper-dependent protein binding	ATOX1	IDA		Human	PMID:31283225
Molecular Function	GO:1903136	cuprous ion binding	ATOX1	IDA		Human	PMID:31283225
Molecular Function	GO:0005515	protein binding	ATOX1	IPI	UniProtKB:P35670	Human	PMID:12968035
Molecular Function	GO:0005515	protein binding	ATOX1	IPI	UniProtKB:Q04656	Human	PMID:21667063
Molecular Function	GO:0005515	protein binding	ATOX1	IPI	UniProtKB:O15431	Human	PMID:24837030
Molecular Function	GO:0005515	protein binding	ATOX1	IPI	UniProtKB:O43822	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ATOX1	IPI	UniProtKB:O95749	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ATOX1	IPI	UniProtKB:Q9NWS6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ATOX1	IPI	UniProtKB:O15431	Human	PMID:26745413
Molecular Function	GO:0005515	protein binding	ATOX1	IPI	UniProtKB:P49747	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATOX1	IPI	UniProtKB:Q8N987	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATOX1	IPI	UniProtKB:Q9NWS6	Human	PMID:32296183
Biological Process	GO:0060003	copper ion export	Atox1	IMP		Rat	PMID:22442359|RGD:8554868
Biological Process	GO:0006825	copper ion transport	Atox1	IMP	MGI:MGI:2158341	Mouse	PMID:11391006
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atox1	IMP	MGI:MGI:2158341	Mouse	PMID:11391006
Biological Process	GO:0043066	negative regulation of apoptotic process	Atox1	IDA		Rat	PMID:10617654|RGD:632006
Biological Process	GO:0006979	response to oxidative stress	Atox1	IDA		Rat	PMID:10617654|RGD:632006

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern