Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Atp13a2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ATP13A2
- Mouse genes Atp13a2
- Rat genes Atp13a2
- Zfish genes atp13a2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp13a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070300	phosphatidic acid binding	ATP13A2	IDA		Human	PMID:26134396
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	ATP13A2	IDA		Human	PMID:26134396
Molecular Function	GO:0015203	polyamine transmembrane transporter activity	ATP13A2	IDA		Human	PMID:31996848
Molecular Function	GO:0005515	protein binding	ATP13A2	IPI	UniProtKB:O14976	Human	PMID:22645275
Molecular Function	GO:0005515	protein binding	ATP13A2	IPI	UniProtKB:O60238	Human	PMID:22645275
Molecular Function	GO:0005515	protein binding	ATP13A2	IPI	UniProtKB:O95070	Human	PMID:22645275
Molecular Function	GO:0005515	protein binding	ATP13A2	IPI	UniProtKB:P11142	Human	PMID:22645275
Molecular Function	GO:0005515	protein binding	ATP13A2	IPI	UniProtKB:Q2M2I8	Human	PMID:22645275
Molecular Function	GO:0005515	protein binding	ATP13A2	IPI	UniProtKB:Q9BT88	Human	PMID:22645275
Molecular Function	GO:0005515	protein binding	ATP13A2	IPI	UniProtKB:Q9UBN7	Human	PMID:22645275
Molecular Function	GO:0005515	protein binding	ATP13A2	IPI	UniProtKB:O75592	Human	PMID:27278822
Cellular Component	GO:0005776	autophagosome	ATP13A2	IDA		Human	PMID:24603074
Cellular Component	GO:0005770	late endosome	ATP13A2	IDA		Human	PMID:25392495
Cellular Component	GO:0031902	late endosome membrane	ATP13A2	IDA		Human	PMID:29505581
Cellular Component	GO:0005765	lysosomal membrane	ATP13A2	HDA		Human	PMID:17897319
Cellular Component	GO:0005765	lysosomal membrane	ATP13A2	IDA		Human	PMID:23499937
Cellular Component	GO:0005765	lysosomal membrane	ATP13A2	IDA		Human	PMID:26134396
Cellular Component	GO:0005765	lysosomal membrane	ATP13A2	IDA		Human	PMID:29505581
Cellular Component	GO:0005764	lysosome	ATP13A2	IDA		Human	PMID:16964263
Cellular Component	GO:0005764	lysosome	ATP13A2	IDA		Human	PMID:21542062
Cellular Component	GO:0005764	lysosome	ATP13A2	IDA		Human	PMID:24603074
Cellular Component	GO:0005764	lysosome	ATP13A2	IDA		Human	PMID:25392495
Cellular Component	GO:0005771	multivesicular body	ATP13A2	IDA		Human	PMID:24603074
Cellular Component	GO:0005771	multivesicular body	ATP13A2	IDA		Human	PMID:25392495
Cellular Component	GO:0043005	neuron projection	ATP13A2	IDA		Human	PMID:22186024
Cellular Component	GO:0043005	neuron projection	Atp13a2	IDA		Mouse	MGI:MGI:5314324\|PMID:22186024
Cellular Component	GO:0043025	neuronal cell body	ATP13A2	IDA		Human	PMID:22186024
Cellular Component	GO:0043025	neuronal cell body	Atp13a2	IDA		Mouse	MGI:MGI:5314324\|PMID:22186024
Cellular Component	GO:0030133	transport vesicle	ATP13A2	IDA		Human	PMID:22186024
Cellular Component	GO:0031982	vesicle	ATP13A2	IDA		Human	PMID:24603074
Cellular Component	GO:0012506	vesicle membrane	Atp13a2	IDA		Mouse	MGI:MGI:5314324\|PMID:22186024
Biological Process	GO:1905037	autophagosome organization	ATP13A2	IDA		Human	PMID:22186024
Biological Process	GO:0061909	autophagosome-lysosome fusion	ATP13A2	IMP		Human	PMID:30538141
Biological Process	GO:0061909	autophagosome-lysosome fusion	Atp13a2	IMP		Mouse	MGI:MGI:6273736\|PMID:30538141
Biological Process	GO:0006914	autophagy	ATP13A2	IMP		Human	PMID:27278822
Biological Process	GO:0006914	autophagy	Atp13a2	IMP		Mouse	MGI:MGI:5881999\|PMID:27278822
Biological Process	GO:0071287	cellular response to manganese ion	ATP13A2	IMP		Human	PMID:22285144
Biological Process	GO:0071287	cellular response to manganese ion	atp13a2	IMP	ZFIN:ZDB-MRPHLNO-210423-1	Zfish	PMID:32954262
Biological Process	GO:0071287	cellular response to manganese ion	atp13a2	IMP	ZFIN:ZDB-GENO-210427-1	Zfish	PMID:32954262
Biological Process	GO:0071287	cellular response to manganese ion	atp13a2	IMP	ZFIN:ZDB-GENO-210427-4	Zfish	PMID:32954262
Biological Process	GO:0071287	cellular response to manganese ion	atp13a2	IMP	ZFIN:ZDB-MRPHLNO-210423-2	Zfish	PMID:32954262
Biological Process	GO:0034599	cellular response to oxidative stress	ATP13A2	IMP		Human	PMID:26134396
Biological Process	GO:0034599	cellular response to oxidative stress	Atp13a2	IMP		Mouse	MGI:MGI:5780535\|PMID:24334770
Biological Process	GO:0021588	cerebellum formation	atp13a2	IMP	ZFIN:ZDB-MRPHLNO-190926-2,ZFIN:ZDB-MRPHLNO-190926-3	Zfish	PMID:30992063
Biological Process	GO:0043009	chordate embryonic development	atp13a2	IMP	ZFIN:ZDB-MRPHLNO-130130-3	Zfish	PMID:23123961
Biological Process	GO:0097734	extracellular exosome biogenesis	ATP13A2	IMP		Human	PMID:25392495
Biological Process	GO:0006874	intracellular calcium ion homeostasis	ATP13A2	IDA		Human	PMID:22186024
Biological Process	GO:0006879	intracellular iron ion homeostasis	ATP13A2	IMP		Human	PMID:26818499
Biological Process	GO:0006882	intracellular zinc ion homeostasis	ATP13A2	IMP		Human	PMID:24334770
Biological Process	GO:0006882	intracellular zinc ion homeostasis	ATP13A2	IMP		Human	PMID:24603074
Biological Process	GO:0006882	intracellular zinc ion homeostasis	Atp13a2	IMP		Mouse	MGI:MGI:5780535\|PMID:24334770
Biological Process	GO:0055088	lipid homeostasis	ATP13A2	IMP		Human	PMID:31132336
Biological Process	GO:0007626	locomotory behavior	atp13a2	IMP	ZFIN:ZDB-MRPHLNO-130130-3	Zfish	PMID:23123961
Biological Process	GO:0007041	lysosomal transport	ATP13A2	IMP		Human	PMID:31996848
Biological Process	GO:0070050	neuron cellular homeostasis	atp13a2	IMP	ZFIN:ZDB-GENO-210413-6	Zfish	PMID:32529115
Biological Process	GO:1990938	peptidyl-aspartic acid autophosphorylation	ATP13A2	IMP		Human	PMID:26134396
Biological Process	GO:1902047	polyamine transmembrane transport	ATP13A2	IDA		Human	PMID:23205587
Biological Process	GO:1903543	positive regulation of exosomal secretion	ATP13A2	IDA		Human	PMID:24603074
Biological Process	GO:1903543	positive regulation of exosomal secretion	ATP13A2	IMP		Human	PMID:25392495
Biological Process	GO:1903543	positive regulation of exosomal secretion	Atp13a2	IMP		Mouse	MGI:MGI:5770036\|PMID:25392495
Biological Process	GO:0010628	positive regulation of gene expression	ATP13A2	IMP		Human	PMID:27278822
Biological Process	GO:0050714	positive regulation of protein secretion	ATP13A2	IMP		Human	PMID:25392495
Biological Process	GO:0061462	protein localization to lysosome	ATP13A2	IMP		Human	PMID:30538141
Biological Process	GO:0061462	protein localization to lysosome	Atp13a2	IMP		Mouse	MGI:MGI:6273736\|PMID:30538141
Biological Process	GO:0016243	regulation of autophagosome size	ATP13A2	IDA		Human	PMID:22186024
Biological Process	GO:0016243	regulation of autophagosome size	Atp13a2	IMP		Rat	PMID:22186024\|RGD:13442482
Biological Process	GO:0052548	regulation of endopeptidase activity	ATP13A2	IMP		Human	PMID:23499937
Biological Process	GO:1905123	regulation of glucosylceramidase activity	Atp13a2	IMP		Mouse	MGI:MGI:5780535\|PMID:24334770
Biological Process	GO:1905165	regulation of lysosomal protein catabolic process	ATP13A2	IMP		Human	PMID:23499937
Biological Process	GO:1905165	regulation of lysosomal protein catabolic process	ATP13A2	IGI	UniProtKB:Q9CTG6	Human	PMID:24334770
Biological Process	GO:1905165	regulation of lysosomal protein catabolic process	Atp13a2	IMP		Mouse	MGI:MGI:5780535\|PMID:24334770
Biological Process	GO:0016241	regulation of macroautophagy	ATP13A2	IMP		Human	PMID:22198378
Biological Process	GO:0010821	regulation of mitochondrion organization	ATP13A2	IDA		Human	PMID:22186024
Biological Process	GO:0010821	regulation of mitochondrion organization	ATP13A2	IMP		Human	PMID:22198378
Biological Process	GO:0010821	regulation of mitochondrion organization	Atp13a2	IMP		Mouse	MGI:MGI:5780537\|PMID:22198378
Biological Process	GO:0010821	regulation of mitochondrion organization	Atp13a2	IMP		Rat	PMID:22186024\|RGD:13442482
Biological Process	GO:1900180	regulation of protein localization to nucleus	ATP13A2	IMP		Human	PMID:27278822
Biological Process	GO:1900180	regulation of protein localization to nucleus	Atp13a2	IMP		Mouse	MGI:MGI:5881999\|PMID:27278822
Biological Process	GO:2000152	regulation of ubiquitin-specific protease activity	ATP13A2	IMP		Human	PMID:27278822
Biological Process	GO:1903710	spermine transmembrane transport	ATP13A2	IMP		Human	PMID:31996848
Biological Process	GO:0097501	stress response to metal ion	atp13a2	IMP	ZFIN:ZDB-GENO-210427-1	Zfish	PMID:32954262
Biological Process	GO:0097501	stress response to metal ion	atp13a2	IMP	ZFIN:ZDB-MRPHLNO-210423-1	Zfish	PMID:32954262
Biological Process	GO:0097501	stress response to metal ion	atp13a2	IMP	ZFIN:ZDB-MRPHLNO-210423-2	Zfish	PMID:32954262
Biological Process	GO:0097501	stress response to metal ion	atp13a2	IMP	ZFIN:ZDB-GENO-210427-4	Zfish	PMID:32954262

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.