Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Atp1a3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ATP1A3
- Mouse genes Atp1a3
- Rat genes Atp1a3
- Zfish genes atp1a3a,atp1a3b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp1a3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001540	amyloid-beta binding	ATP1A3	IDA		Human	PMID:26224839
Molecular Function	GO:0001540	amyloid-beta binding	Atp1a3	IDA		Rat	PMID:26224839\|RGD:11576284
Molecular Function	GO:0001540	amyloid-beta binding	Atp1a3	IPI	RGD:736021	Rat	PMID:26224839\|RGD:11576284
Molecular Function	GO:0031748	D1 dopamine receptor binding	Atp1a3	IPI	RGD:2518	Rat	PMID:21809413\|RGD:7248609
Molecular Function	GO:0043395	heparan sulfate proteoglycan binding	Atp1a3	IPI	UniProtKB:A2ASQ1	Mouse	MGI:MGI:4352602\|PMID:19376779
Molecular Function	GO:0005391	P-type sodium:potassium-exchanging transporter activity	ATP1A3	IDA		Human	PMID:10636900
Molecular Function	GO:0005391	P-type sodium:potassium-exchanging transporter activity	ATP1A3	IMP		Human	PMID:15260953
Molecular Function	GO:0086037	P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential	Atp1a3	IGI	UniProtKB:A2ASQ1	Mouse	MGI:MGI:4352602\|PMID:19376779
Molecular Function	GO:0005515	protein binding	ATP1A3	IPI	UniProtKB:P12757	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP1A3	IPI	UniProtKB:P15923-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP1A3	IPI	UniProtKB:P17024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP1A3	IPI	UniProtKB:Q08AE8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP1A3	IPI	UniProtKB:Q08AM6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP1A3	IPI	UniProtKB:Q0VD86	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP1A3	IPI	UniProtKB:Q12888	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP1A3	IPI	UniProtKB:Q6NXG1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP1A3	IPI	UniProtKB:Q6XD76	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP1A3	IPI	UniProtKB:Q6ZQX7-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP1A3	IPI	UniProtKB:Q6ZSB9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP1A3	IPI	UniProtKB:Q96PV4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP1A3	IPI	UniProtKB:Q99504	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP1A3	IPI	UniProtKB:Q9GZQ6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP1A3	IPI	UniProtKB:Q9H7C4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP1A3	IPI	UniProtKB:Q9UMX3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP1A3	IPI	UniProtKB:Q9UQM7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Atp1a3	IPI	RGD:620830	Rat	PMID:12093728\|RGD:631775
Molecular Function	GO:0005515	protein binding	Atp1a3	IPI	RGD:619787	Rat	PMID:16025302\|RGD:10043786
Molecular Function	GO:0005515	protein binding	Atp1a3	IPI	RGD:619788	Rat	PMID:16025302\|RGD:10043786
Molecular Function	GO:0005515	protein binding	Atp1a3	IPI	UniProtKB:P25304	Rat	PMID:16630822\|RGD:8553868
Molecular Function	GO:0051087	protein-folding chaperone binding	ATP1A3	IPI	UniProtKB:P05026	Human	PMID:10636900
Molecular Function	GO:0051087	protein-folding chaperone binding	ATP1A3	IPI	UniProtKB:P14415	Human	PMID:10636900
Molecular Function	GO:0051087	protein-folding chaperone binding	ATP1A3	IPI	UniProtKB:P54709	Human	PMID:10636900
Cellular Component	GO:0030424	axon	ATP1A3	IDA		Human	PMID:26224839
Cellular Component	GO:0030424	axon	Atp1a3	IDA		Rat	PMID:12617948\|RGD:1581764
Cellular Component	GO:0044305	calyx of Held	Atp1a3	IDA		Rat	PMID:17220883\|RGD:13702313
Cellular Component	GO:0005737	cytoplasm	Atp1a3	IDA		Mouse	PMID:10837135
Cellular Component	GO:0044327	dendritic spine head	Atp1a3	IDA		Rat	PMID:21809413\|RGD:7248609
Cellular Component	GO:0044326	dendritic spine neck	Atp1a3	IDA		Rat	PMID:21809413\|RGD:7248609
Cellular Component	GO:0005783	endoplasmic reticulum	ATP1A3	IDA		Human	PMID:15260953
Cellular Component	GO:1903561	extracellular vesicle	ATP1A3	HDA		Human	PMID:24769233
Cellular Component	GO:0005794	Golgi apparatus	ATP1A3	IDA		Human	PMID:15260953
Cellular Component	GO:0016020	membrane	Atp1a3	IDA		Rat	PMID:26224839\|RGD:11576284
Cellular Component	GO:0043209	myelin sheath	Atp1a3	HDA		Mouse	MGI:MGI:3834050\|PMID:17634366
Cellular Component	GO:0043209	myelin sheath	Atp1a3	IDA		Rat	PMID:12617948\|RGD:1581764
Cellular Component	GO:0043209	myelin sheath	Atp1a3	IDA		Rat	PMID:17960831\|RGD:10047364
Cellular Component	GO:0098984	neuron to neuron synapse	Atp1a3	IDA		Mouse	MGI:MGI:4939095\|PMID:21196491
Cellular Component	GO:0043025	neuronal cell body	ATP1A3	IDA		Human	PMID:26224839
Cellular Component	GO:0005634	nucleus	Atp1a3	IDA		Mouse	PMID:10837135
Cellular Component	GO:0031090	organelle membrane	ATP1A3	IGI	UniProtKB:P05026	Human	PMID:19751721
Cellular Component	GO:0001917	photoreceptor inner segment	Atp1a3	IDA		Mouse	MGI:MGI:4939095\|PMID:21196491
Cellular Component	GO:0005886	plasma membrane	ATP1A3	IDA		Human	PMID:15260953
Cellular Component	GO:0005886	plasma membrane	ATP1A3	IGI	UniProtKB:P05026	Human	PMID:19751721
Cellular Component	GO:0098794	postsynapse	Atp1a3	IDA		Rat	PMID:19082858\|RGD:13702444
Cellular Component	GO:0042734	presynaptic membrane	Atp1a3	IDA		Rat	PMID:17220883\|RGD:13702313
Cellular Component	GO:0042734	presynaptic membrane	Atp1a3	IDA		Rat	PMID:19082858\|RGD:13702444
Cellular Component	GO:0042383	sarcolemma	Atp1a3	IDA		Mouse	MGI:MGI:4352602\|PMID:19376779
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	ATP1A3	IDA		Human	PMID:10636900
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	Atp1a3	IDA		Mouse	MGI:MGI:4352602\|PMID:19376779
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	Atp1a3	IDA		Rat	PMID:12093728\|RGD:631775
Cellular Component	GO:0045202	synapse	Atp1a3	IDA		Rat	PMID:16630822\|RGD:8553868
Biological Process	GO:0008344	adult locomotory behavior	Atp1a3	IMP	MGI:MGI:3696954	Mouse	PMID:17234593
Biological Process	GO:0060048	cardiac muscle contraction	Atp1a3	IDA		Mouse	MGI:MGI:4352602\|PMID:19376779
Biological Process	GO:1904646	cellular response to amyloid-beta	Atp1a3	IDA		Rat	PMID:26224839\|RGD:11576284
Biological Process	GO:0071300	cellular response to retinoic acid	Atp1a3	IEP		Rat	PMID:8944660\|RGD:11576286
Biological Process	GO:0097067	cellular response to thyroid hormone stimulus	Atp1a3	IEP		Rat	PMID:8944660\|RGD:11576286
Biological Process	GO:0021987	cerebral cortex development	Atp1a3	IEP		Rat	PMID:19362129\|RGD:11576282
Biological Process	GO:0030007	intracellular potassium ion homeostasis	ATP1A3	IDA		Human	PMID:10636900
Biological Process	GO:0006883	intracellular sodium ion homeostasis	ATP1A3	IDA		Human	PMID:10636900
Biological Process	GO:0006883	intracellular sodium ion homeostasis	Atp1a3	IDA		Mouse	MGI:MGI:4352602\|PMID:19376779
Biological Process	GO:0035235	ionotropic glutamate receptor signaling pathway	Atp1a3	IMP	MGI:MGI:3696954	Mouse	PMID:17234593
Biological Process	GO:0007626	locomotory behavior	atp1a3a	IMP	ZFIN:ZDB-MRPHLNO-130410-11	Zfish	PMID:23400780
Biological Process	GO:0007626	locomotory behavior	atp1a3b	IMP	ZFIN:ZDB-MRPHLNO-130603-3	Zfish	PMID:23400780
Biological Process	GO:0007613	memory	Atp1a3	IMP	MGI:MGI:3696954	Mouse	PMID:17234593
Biological Process	GO:1990535	neuron projection maintenance	ATP1A3	IGI	UniProtKB:P05067	Human	PMID:26224839
Biological Process	GO:1990573	potassium ion import across plasma membrane	ATP1A3	IDA		Human	PMID:10636900
Biological Process	GO:0006813	potassium ion transport	Atp1a3	IDA		Rat	PMID:12093728\|RGD:631775
Biological Process	GO:0086036	regulation of cardiac muscle cell membrane potential	Atp1a3	IGI	UniProtKB:A2ASQ1	Mouse	MGI:MGI:4352602\|PMID:19376779
Biological Process	GO:0009410	response to xenobiotic stimulus	Atp1a3	IMP	MGI:MGI:3696954	Mouse	PMID:17234593
Biological Process	GO:0036376	sodium ion export across plasma membrane	ATP1A3	IDA		Human	PMID:10636900
Biological Process	GO:0036376	sodium ion export across plasma membrane	Atp1a3	IDA		Mouse	MGI:MGI:4352602\|PMID:19376779
Biological Process	GO:0006814	sodium ion transport	Atp1a3	IDA		Rat	PMID:12093728\|RGD:631775
Biological Process	GO:0021591	ventricular system development	atp1a3a	IMP	ZFIN:ZDB-MRPHLNO-130603-4	Zfish	PMID:23400780
Biological Process	GO:0021591	ventricular system development	atp1a3a	IMP	ZFIN:ZDB-MRPHLNO-130410-11	Zfish	PMID:23400780
Biological Process	GO:0021591	ventricular system development	atp1a3b	IMP	ZFIN:ZDB-MRPHLNO-130603-3	Zfish	PMID:23400780
Biological Process	GO:0021591	ventricular system development	atp1a3b	IMP	ZFIN:ZDB-MRPHLNO-130603-5	Zfish	PMID:23400780
Biological Process	GO:0008542	visual learning	Atp1a3	IMP	MGI:MGI:3696954	Mouse	PMID:17234593

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 08/21/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.