Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATP1A4
  • Mouse genes Atp1a4
  • Rat genes Atp1a4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp1a4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	ATP1A4	IGI	UniProtKB:P05026|UniProtKB:P54709	Human	PMID:16861705
Molecular Function	GO:0005391	P-type sodium:potassium-exchanging transporter activity	ATP1A4	IGI	UniProtKB:P05026|UniProtKB:P54709	Human	PMID:16861705
Molecular Function	GO:0005391	P-type sodium:potassium-exchanging transporter activity	Atp1a4	IDA		Mouse	PMID:23229519
Molecular Function	GO:0005391	P-type sodium:potassium-exchanging transporter activity	Atp1a4	IMP	MGI:MGI:4941050	Mouse	PMID:21187400
Molecular Function	GO:0005391	P-type sodium:potassium-exchanging transporter activity	Atp1a4	IDA		Rat	PMID:10555956|RGD:8553802
Molecular Function	GO:0005515	protein binding	ATP1A4	IPI	UniProtKB:P05026	Human	PMID:16861705
Molecular Function	GO:0005515	protein binding	ATP1A4	IPI	UniProtKB:P54709	Human	PMID:16861705
Cellular Component	GO:0097733	photoreceptor cell cilium	ATP1A4	IDA		Human	PMID:26373354
Cellular Component	GO:0120200	rod photoreceptor outer segment	ATP1A4	IDA		Human	PMID:26373354
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	ATP1A4	IPI	UniProtKB:P05026|UniProtKB:P54709	Human	PMID:16861705
Cellular Component	GO:0097225	sperm midpiece	ATP1A4	IDA		Human	PMID:16861705
Biological Process	GO:0051649	establishment of localization in cell	Atp1a4	IMP	MGI:MGI:4941050	Mouse	PMID:21187400
Biological Process	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient	Atp1a4	IMP	MGI:MGI:4941050	Mouse	MGI:MGI:4940952|PMID:21187400
Biological Process	GO:0009566	fertilization	Atp1a4	IMP	MGI:MGI:4941050	Mouse	PMID:21187400
Biological Process	GO:0030317	flagellated sperm motility	ATP1A4	IDA		Human	PMID:12112599
Biological Process	GO:0030317	flagellated sperm motility	ATP1A4	IMP		Human	PMID:16861705
Biological Process	GO:0030317	flagellated sperm motility	Atp1a4	IMP	MGI:MGI:4941050	Mouse	PMID:21187400
Biological Process	GO:0030317	flagellated sperm motility	Atp1a4	IDA		Rat	PMID:12112599|RGD:728364
Biological Process	GO:0071805	potassium ion transmembrane transport	ATP1A4	IGI	UniProtKB:P05026|UniProtKB:P54709	Human	PMID:16861705
Biological Process	GO:0071805	potassium ion transmembrane transport	Atp1a4	IMP	MGI:MGI:4941050	Mouse	MGI:MGI:4940952|PMID:21187400
Biological Process	GO:0030641	regulation of cellular pH	ATP1A4	IDA		Human	PMID:12112599
Biological Process	GO:0030641	regulation of cellular pH	Atp1a4	IDA		Rat	PMID:12112599|RGD:728364
Biological Process	GO:0042391	regulation of membrane potential	Atp1a4	IMP	MGI:MGI:4941050	Mouse	PMID:21187400
Biological Process	GO:0035725	sodium ion transmembrane transport	ATP1A4	IGI	UniProtKB:P05026|UniProtKB:P54709	Human	PMID:16861705
Biological Process	GO:0035725	sodium ion transmembrane transport	Atp1a4	IMP	MGI:MGI:4941050	Mouse	MGI:MGI:4940952|PMID:21187400
Biological Process	GO:0006814	sodium ion transport	Atp1a4	IMP	MGI:MGI:4941050	Mouse	PMID:21187400
Biological Process	GO:0007283	spermatogenesis	Atp1a4	IMP	MGI:MGI:4941050	Mouse	PMID:21187400
Biological Process	GO:0007283	spermatogenesis	Atp1a4	IEP		Rat	PMID:16264093|RGD:6903234

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern