Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Atp1b1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ATP1B1
- Mouse genes Atp1b1
- Rat genes Atp1b1
- Zfish genes atp1b1a,atp1b1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp1b1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001671	ATPase activator activity	ATP1B1	IDA		Human	PMID:10636900
Molecular Function	GO:0001671	ATPase activator activity	ATP1B1	IGI	UniProtKB:Q13733	Human	PMID:16861705
Molecular Function	GO:0001671	ATPase activator activity	ATP1B1	IGI	UniProtKB:P50993	Human	PMID:18728015
Molecular Function	GO:0001671	ATPase activator activity	ATP1B1	IDA		Human	PMID:19542013
Molecular Function	GO:0001671	ATPase activator activity	ATP1B1	IGI	UniProtKB:P50993	Human	PMID:20100892
Molecular Function	GO:0001671	ATPase activator activity	ATP1B1	IDA		Human	PMID:23954377
Molecular Function	GO:0001671	ATPase activator activity	Atp1b1	IMP		Mouse	MGI:MGI:4359299\|PMID:19683723
Molecular Function	GO:0051117	ATPase binding	ATP1B1	IPI	UniProtKB:P05023	Human	PMID:10636900
Molecular Function	GO:0051117	ATPase binding	ATP1B1	IPI	UniProtKB:P13637	Human	PMID:10636900
Molecular Function	GO:0051117	ATPase binding	ATP1B1	IPI	UniProtKB:P50993	Human	PMID:10636900
Molecular Function	GO:0051117	ATPase binding	ATP1B1	IPI	UniProtKB:Q13733	Human	PMID:16861705
Molecular Function	GO:0051117	ATPase binding	ATP1B1	IPI	UniProtKB:P50993	Human	PMID:23954377
Molecular Function	GO:0023026	MHC class II protein complex binding	ATP1B1	HDA		Human	PMID:20458337
Molecular Function	GO:0005391	P-type sodium:potassium-exchanging transporter activity	Atp1b1	IDA		Rat	PMID:16624992\|RGD:2302992
Molecular Function	GO:0005515	protein binding	ATP1B1	IPI	UniProtKB:O76024	Human	PMID:17947299
Molecular Function	GO:0005515	protein binding	ATP1B1	IPI	UniProtKB:Q15049	Human	PMID:22328087
Molecular Function	GO:0005515	protein binding	ATP1B1	IPI	UniProtKB:P02730	Human	PMID:25012180
Molecular Function	GO:0005515	protein binding	ATP1B1	IPI	UniProtKB:P05023	Human	PMID:25012180
Molecular Function	GO:0005515	protein binding	ATP1B1	IPI	UniProtKB:Q8IZU9	Human	PMID:25902260
Molecular Function	GO:0005515	protein binding	ATP1B1	IPI	UniProtKB:P30556	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	ATP1B1	IPI	UniProtKB:P05023	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	ATP1B1	IPI	UniProtKB:P61278:PRO_0000033087	Human	PMID:31136617
Molecular Function	GO:0005515	protein binding	ATP1B1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Atp1b1	IPI	UniProtKB:Q8BX57-1\|UniProtKB:Q8BX57-2	Mouse	MGI:MGI:3588605\|PMID:16135750
Molecular Function	GO:0005515	protein binding	Atp1b1	IPI	PR:Q9ER97	Mouse	PMID:22079573
Molecular Function	GO:0005515	protein binding	Atp1b1	IPI	PR:Q9D035	Mouse	PMID:17606467
Molecular Function	GO:0005515	protein binding	Atp1b1	IPI	UniProtKB:P54708	Rat	PMID:14749213\|RGD:42722003
Molecular Function	GO:0046982	protein heterodimerization activity	Atp1b1	IPI	UniProtKB:P06685	Rat	PMID:28787093\|RGD:14995309
Molecular Function	GO:0019901	protein kinase binding	Atp1b1	IPI	UniProtKB:A2AAJ9	Mouse	MGI:MGI:5494790\|PMID:23392350
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ATP1B1	IDA		Human	PMID:10636900
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ATP1B1	IGI	UniProtKB:Q13733	Human	PMID:16861705
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ATP1B1	IDA		Human	PMID:18075585
Cellular Component	GO:0016324	apical plasma membrane	ATP1B1	IDA		Human	PMID:11193188
Cellular Component	GO:0016324	apical plasma membrane	Atp1b1	IDA		Mouse	PMID:21705333
Cellular Component	GO:0016324	apical plasma membrane	Atp1b1	IDA		Rat	PMID:14749213\|RGD:42722003
Cellular Component	GO:0016324	apical plasma membrane	Atp1b1	IDA		Rat	PMID:15327400\|RGD:2302991
Cellular Component	GO:0016323	basolateral plasma membrane	Atp1b1	IDA		Mouse	PMID:10837135
Cellular Component	GO:0016323	basolateral plasma membrane	Atp1b1	IDA		Rat	PMID:15327400\|RGD:2302991
Cellular Component	GO:0005901	caveola	Atp1b1	IDA		Rat	PMID:16624992\|RGD:2302992
Cellular Component	GO:0070062	extracellular exosome	ATP1B1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	ATP1B1	HDA		Human	PMID:23533145
Cellular Component	GO:1903561	extracellular vesicle	ATP1B1	HDA		Human	PMID:24769233
Cellular Component	GO:0014704	intercalated disc	Atp1b1	IMP		Mouse	MGI:MGI:4359299\|PMID:19683723
Cellular Component	GO:0016328	lateral plasma membrane	ATP1B1	IDA		Human	PMID:11193188
Cellular Component	GO:0016020	membrane	ATP1B1	IDA		Human	PMID:23954377
Cellular Component	GO:0016020	membrane	Atp1b1	IDA		Rat	PMID:28787093\|RGD:14995309
Cellular Component	GO:0043209	myelin sheath	Atp1b1	HDA		Mouse	MGI:MGI:3834050\|PMID:17634366
Cellular Component	GO:0031090	organelle membrane	ATP1B1	IGI	UniProtKB:P05023\|UniProtKB:P13637\|UniProtKB:P50993	Human	PMID:19751721
Cellular Component	GO:0005886	plasma membrane	ATP1B1	IDA		Human	PMID:18522992
Cellular Component	GO:0005886	plasma membrane	ATP1B1	IGI	UniProtKB:P05023\|UniProtKB:P13637\|UniProtKB:P50993	Human	PMID:19751721
Cellular Component	GO:0005886	plasma membrane	Atp1b1	IDA		Mouse	PMID:10837135
Cellular Component	GO:0042383	sarcolemma	Atp1b1	IMP		Mouse	MGI:MGI:4359299\|PMID:19683723
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	ATP1B1	IDA		Human	PMID:10636900
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	ATP1B1	IPI	UniProtKB:Q13733	Human	PMID:16861705
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	ATP1B1	IGI	UniProtKB:P50993	Human	PMID:18728015
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	ATP1B1	IDA		Human	PMID:19542013
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	ATP1B1	IDA		Human	PMID:23954377
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	Atp1b1	IMP		Mouse	MGI:MGI:4359299\|PMID:19683723
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	Atp1b1	IDA		Rat	PMID:16624992\|RGD:2302992
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	Atp1b1	IDA		Rat	PMID:28787093\|RGD:14995309
Cellular Component	GO:0036126	sperm flagellum	ATP1B1	IDA		Human	PMID:16861705
Cellular Component	GO:0030315	T-tubule	ATP1B1	IGI	UniProtKB:P05023\|UniProtKB:P50993	Human	PMID:19751721
Biological Process	GO:0046034	ATP metabolic process	ATP1B1	IDA		Human	PMID:23954377
Biological Process	GO:0001824	blastocyst development	Atp1b1	IMP		Mouse	MGI:MGI:1888635
Biological Process	GO:0060048	cardiac muscle contraction	Atp1b1	IMP		Mouse	MGI:MGI:4359299\|PMID:19683723
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	atp1b1a	IMP	ZFIN:ZDB-GENO-170202-20	Zfish	PMID:27240166
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Atp1b1	IMP		Mouse	MGI:MGI:4359299\|PMID:19683723
Biological Process	GO:0030007	intracellular potassium ion homeostasis	ATP1B1	IDA		Human	PMID:10636900
Biological Process	GO:0030007	intracellular potassium ion homeostasis	ATP1B1	IDA		Human	PMID:19542013
Biological Process	GO:0006883	intracellular sodium ion homeostasis	ATP1B1	IDA		Human	PMID:10636900
Biological Process	GO:0006883	intracellular sodium ion homeostasis	ATP1B1	IDA		Human	PMID:19542013
Biological Process	GO:0086009	membrane repolarization	ATP1B1	IDA		Human	PMID:19542013
Biological Process	GO:0030001	metal ion transport	Atp1b1	IDA		Rat	PMID:15327400\|RGD:2302991
Biological Process	GO:0098655	monoatomic cation transmembrane transport	ATP1B1	IGI	UniProtKB:P50993	Human	PMID:20100892
Biological Process	GO:0032781	positive regulation of ATP-dependent activity	ATP1B1	IDA		Human	PMID:10636900
Biological Process	GO:1903281	positive regulation of calcium:sodium antiporter activity	Atp1b1	IMP		Mouse	MGI:MGI:4359299\|PMID:19683723
Biological Process	GO:1903408	positive regulation of P-type sodium:potassium-exchanging transporter activity	ATP1B1	IDA		Human	PMID:10636900
Biological Process	GO:1903408	positive regulation of P-type sodium:potassium-exchanging transporter activity	ATP1B1	IGI	UniProtKB:P50993	Human	PMID:18728015
Biological Process	GO:1903408	positive regulation of P-type sodium:potassium-exchanging transporter activity	ATP1B1	IDA		Human	PMID:19542013
Biological Process	GO:1903408	positive regulation of P-type sodium:potassium-exchanging transporter activity	ATP1B1	IGI	UniProtKB:P50993	Human	PMID:20100892
Biological Process	GO:1903408	positive regulation of P-type sodium:potassium-exchanging transporter activity	ATP1B1	IGI	UniProtKB:Q13733	Human	PMID:20100892
Biological Process	GO:1903408	positive regulation of P-type sodium:potassium-exchanging transporter activity	ATP1B1	IDA		Human	PMID:23954377
Biological Process	GO:1903408	positive regulation of P-type sodium:potassium-exchanging transporter activity	Atp1b1	IMP		Mouse	MGI:MGI:4359299\|PMID:19683723
Biological Process	GO:1903288	positive regulation of potassium ion import across plasma membrane	ATP1B1	IDA		Human	PMID:10636900
Biological Process	GO:1903288	positive regulation of potassium ion import across plasma membrane	ATP1B1	IGI	UniProtKB:Q13733	Human	PMID:16861705
Biological Process	GO:1903288	positive regulation of potassium ion import across plasma membrane	ATP1B1	IGI	UniProtKB:P50993	Human	PMID:18728015
Biological Process	GO:1903288	positive regulation of potassium ion import across plasma membrane	ATP1B1	IDA		Human	PMID:19542013
Biological Process	GO:1903288	positive regulation of potassium ion import across plasma membrane	ATP1B1	IGI	UniProtKB:P50993	Human	PMID:20100892
Biological Process	GO:1903288	positive regulation of potassium ion import across plasma membrane	ATP1B1	IGI	UniProtKB:Q13733	Human	PMID:20100892
Biological Process	GO:1903288	positive regulation of potassium ion import across plasma membrane	ATP1B1	IDA		Human	PMID:23954377
Biological Process	GO:1901018	positive regulation of potassium ion transmembrane transporter activity	ATP1B1	IDA		Human	PMID:10636900
Biological Process	GO:1903278	positive regulation of sodium ion export across plasma membrane	ATP1B1	IDA		Human	PMID:10636900
Biological Process	GO:1903278	positive regulation of sodium ion export across plasma membrane	ATP1B1	IGI	UniProtKB:P50993	Human	PMID:18728015
Biological Process	GO:1903278	positive regulation of sodium ion export across plasma membrane	ATP1B1	IDA		Human	PMID:19542013
Biological Process	GO:1990573	potassium ion import across plasma membrane	Atp1b1	IMP		Mouse	MGI:MGI:4359299\|PMID:19683723
Biological Process	GO:0006813	potassium ion transport	Atp1b1	IDA		Rat	PMID:16624992\|RGD:2302992
Biological Process	GO:0072659	protein localization to plasma membrane	ATP1B1	IDA		Human	PMID:18522992
Biological Process	GO:0050821	protein stabilization	ATP1B1	IDA		Human	PMID:10636900
Biological Process	GO:0050821	protein stabilization	Atp1b1	IMP		Mouse	MGI:MGI:4359299\|PMID:19683723
Biological Process	GO:1903169	regulation of calcium ion transmembrane transport	Atp1b1	IMP		Mouse	MGI:MGI:4359299\|PMID:19683723
Biological Process	GO:0098901	regulation of cardiac muscle cell action potential	atp1b1a	IMP	ZFIN:ZDB-MRPHLNO-060622-5	Zfish	PMID:24952909
Biological Process	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	Atp1b1	IMP		Mouse	MGI:MGI:4359299\|PMID:19683723
Biological Process	GO:0045682	regulation of epidermis development	atp1b1a	IMP	ZFIN:ZDB-GENO-080730-3	Zfish	PMID:18351656
Biological Process	GO:0010468	regulation of gene expression	Atp1b1	IMP		Mouse	MGI:MGI:4359299\|PMID:19683723
Biological Process	GO:0055119	relaxation of cardiac muscle	Atp1b1	IMP		Mouse	MGI:MGI:4359299\|PMID:19683723
Biological Process	GO:0001666	response to hypoxia	Atp1b1	IDA		Rat	PMID:12573531\|RGD:631759
Biological Process	GO:0098773	skin epidermis development	atp1b1a	IMP	ZFIN:ZDB-GENO-170202-20	Zfish	PMID:27240166
Biological Process	GO:0036376	sodium ion export across plasma membrane	ATP1B1	IDA		Human	PMID:10636900
Biological Process	GO:0036376	sodium ion export across plasma membrane	Atp1b1	IMP		Mouse	MGI:MGI:4359299\|PMID:19683723
Biological Process	GO:0035725	sodium ion transmembrane transport	ATP1B1	IGI	UniProtKB:Q13733	Human	PMID:16861705
Biological Process	GO:0006814	sodium ion transport	Atp1b1	IDA		Rat	PMID:16624992\|RGD:2302992

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.