Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Atp1b2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ATP1B2
- Mouse genes Atp1b2
- Rat genes Atp1b2
- Zfish genes atp1b2a,atp1b2b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp1b2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001671	ATPase activator activity	ATP1B2	IDA		Human	PMID:10636900
Molecular Function	GO:0001671	ATPase activator activity	ATP1B2	IDA		Human	PMID:19542013
Molecular Function	GO:0051117	ATPase binding	ATP1B2	IPI	UniProtKB:P05023	Human	PMID:10636900
Molecular Function	GO:0051117	ATPase binding	ATP1B2	IPI	UniProtKB:P13637	Human	PMID:10636900
Molecular Function	GO:0051117	ATPase binding	ATP1B2	IPI	UniProtKB:P50993	Human	PMID:10636900
Molecular Function	GO:0005391	P-type sodium:potassium-exchanging transporter activity	Atp1b2	IDA		Rat	PMID:12562669\|RGD:631758
Molecular Function	GO:0005515	protein binding	ATP1B2	IPI	UniProtKB:P05023	Human	PMID:11027149
Molecular Function	GO:0046982	protein heterodimerization activity	Atp1b2	IPI	UniProtKB:P06685	Rat	PMID:28787093\|RGD:14995309
Molecular Function	GO:0046982	protein heterodimerization activity	Atp1b2	IPI	UniProtKB:P06686	Rat	PMID:28787093\|RGD:14995309
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ATP1B2	IDA		Human	PMID:10636900
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ATP1B2	IDA		Human	PMID:19542013
Cellular Component	GO:0016324	apical plasma membrane	ATP1B2	IDA		Human	PMID:11193188
Cellular Component	GO:0016324	apical plasma membrane	Atp1b2	IDA		Mouse	PMID:21705333
Cellular Component	GO:0016324	apical plasma membrane	Atp1b2	IDA		Rat	PMID:12562669\|RGD:631758
Cellular Component	GO:0097450	astrocyte end-foot	Atp1b2	IDA		Mouse	MGI:MGI:6368077\|PMID:2438288
Cellular Component	GO:0097449	astrocyte projection	ATP1B2	IDA		Human	PMID:12887597
Cellular Component	GO:0097449	astrocyte projection	Atp1b2	IDA		Mouse	MGI:MGI:6368052\|PMID:28373281
Cellular Component	GO:0097449	astrocyte projection	Atp1b2	IDA		Mouse	MGI:MGI:6368077\|PMID:2438288
Cellular Component	GO:0044298	cell body membrane	Atp1b2	IDA		Mouse	MGI:MGI:6368052\|PMID:28373281
Cellular Component	GO:0071944	cell periphery	Atp1b2	IDA		Rat	PMID:15294280\|RGD:14995308
Cellular Component	GO:0031253	cell projection membrane	Atp1b2	IDA		Mouse	MGI:MGI:6368052\|PMID:28373281
Cellular Component	GO:0005737	cytoplasm	Atp1b2	IDA		Mouse	PMID:10859164
Cellular Component	GO:0009897	external side of plasma membrane	Atp1b2	IDA		Mouse	MGI:MGI:6368077\|PMID:2438288
Cellular Component	GO:0016328	lateral plasma membrane	ATP1B2	IDA		Human	PMID:11193188
Cellular Component	GO:0016020	membrane	Atp1b2	IDA		Rat	PMID:28787093\|RGD:14995309
Cellular Component	GO:0098984	neuron to neuron synapse	Atp1b2	IDA		Mouse	MGI:MGI:4939095\|PMID:21196491
Cellular Component	GO:0001917	photoreceptor inner segment	Atp1b2	IDA		Mouse	MGI:MGI:4939095\|PMID:21196491
Cellular Component	GO:0005886	plasma membrane	Atp1b2	IMP		Mouse	MGI:MGI:6368052\|PMID:28373281
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	ATP1B2	IDA		Human	PMID:10636900
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	ATP1B2	IDA		Human	PMID:19542013
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	Atp1b2	IDA		Rat	PMID:28787093\|RGD:14995309
Biological Process	GO:0031589	cell-substrate adhesion	Atp1b2	IDA		Mouse	MGI:MGI:6377184\|PMID:12887597
Biological Process	GO:0007507	heart development	atp1b2b	IGI	ZFIN:ZDB-GENE-050327-93	Zfish	PMID:18799547
Biological Process	GO:0007507	heart development	atp1b2b	IMP	ZFIN:ZDB-MRPHLNO-081231-6	Zfish	PMID:18799547
Biological Process	GO:0042472	inner ear morphogenesis	atp1b2b	IGI	ZFIN:ZDB-GENE-050327-93	Zfish	PMID:18799547
Biological Process	GO:0042472	inner ear morphogenesis	atp1b2b	IMP	ZFIN:ZDB-MRPHLNO-081231-6	Zfish	PMID:18799547
Biological Process	GO:0030007	intracellular potassium ion homeostasis	ATP1B2	IDA		Human	PMID:10636900
Biological Process	GO:0030007	intracellular potassium ion homeostasis	ATP1B2	IDA		Human	PMID:19542013
Biological Process	GO:0006883	intracellular sodium ion homeostasis	ATP1B2	IDA		Human	PMID:10636900
Biological Process	GO:0006883	intracellular sodium ion homeostasis	ATP1B2	IDA		Human	PMID:19542013
Biological Process	GO:0021670	lateral ventricle development	Atp1b2	IMP		Mouse	MGI:MGI:69165\|PMID:7525597
Biological Process	GO:0086009	membrane repolarization	ATP1B2	IDA		Human	PMID:19542013
Biological Process	GO:0061744	motor behavior	Atp1b2	IMP		Mouse	MGI:MGI:69165\|PMID:7525597
Biological Process	GO:1903976	negative regulation of glial cell migration	Atp1b2	IDA		Mouse	MGI:MGI:6377184\|PMID:12887597
Biological Process	GO:0021944	neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration	Atp1b2	IMP		Mouse	MGI:MGI:6368077\|PMID:2438288
Biological Process	GO:0048840	otolith development	atp1b2b	IMP	ZFIN:ZDB-MRPHLNO-060622-6	Zfish	PMID:16566913
Biological Process	GO:0048840	otolith development	atp1b2b	IMP	ZFIN:ZDB-MRPHLNO-060626-8	Zfish	PMID:16566913
Biological Process	GO:0048840	otolith development	atp1b2b	IGI	ZFIN:ZDB-MRPHLNO-060215-3,ZFIN:ZDB-MRPHLNO-060626-8	Zfish	PMID:16566913
Biological Process	GO:0045494	photoreceptor cell maintenance	Atp1b2	IMP		Mouse	MGI:MGI:69165\|PMID:7525597
Biological Process	GO:0120036	plasma membrane bounded cell projection organization	Atp1b2	IMP		Mouse	MGI:MGI:69165\|PMID:7525597
Biological Process	GO:0032781	positive regulation of ATP-dependent activity	ATP1B2	IDA		Human	PMID:10636900
Biological Process	GO:0010976	positive regulation of neuron projection development	Atp1b2	IDA		Mouse	MGI:MGI:6368299\|PMID:7504672
Biological Process	GO:1903288	positive regulation of potassium ion import across plasma membrane	ATP1B2	IDA		Human	PMID:10636900
Biological Process	GO:1901018	positive regulation of potassium ion transmembrane transporter activity	ATP1B2	IDA		Human	PMID:10636900
Biological Process	GO:1903278	positive regulation of sodium ion export across plasma membrane	ATP1B2	IDA		Human	PMID:10636900
Biological Process	GO:0048923	posterior lateral line neuromast hair cell differentiation	atp1b2b	IMP	ZFIN:ZDB-MRPHLNO-081231-6	Zfish	PMID:18799547
Biological Process	GO:0048923	posterior lateral line neuromast hair cell differentiation	atp1b2b	IGI	ZFIN:ZDB-GENE-050327-93	Zfish	PMID:18799547
Biological Process	GO:1990573	potassium ion import across plasma membrane	ATP1B2	IDA		Human	PMID:10636900
Biological Process	GO:1990573	potassium ion import across plasma membrane	ATP1B2	IDA		Human	PMID:19542013
Biological Process	GO:0050821	protein stabilization	ATP1B2	IDA		Human	PMID:10636900
Biological Process	GO:0001895	retina homeostasis	Atp1b2	IMP		Mouse	MGI:MGI:2159503\|PMID:8793730
Biological Process	GO:0036376	sodium ion export across plasma membrane	ATP1B2	IDA		Human	PMID:10636900
Biological Process	GO:0036376	sodium ion export across plasma membrane	ATP1B2	IDA		Human	PMID:19542013
Biological Process	GO:0001964	startle response	atp1b2b	IMP	ZFIN:ZDB-MRPHLNO-081231-6	Zfish	PMID:18799547
Biological Process	GO:0001964	startle response	atp1b2b	IGI	ZFIN:ZDB-GENE-050327-93	Zfish	PMID:18799547
Biological Process	GO:0021678	third ventricle development	Atp1b2	IMP		Mouse	MGI:MGI:69165\|PMID:7525597

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.