Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATP2A3
  • Mouse genes Atp2a3
  • Rat genes Atp2a3
  • Zfish genes atp2a3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp2a3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015085	calcium ion transmembrane transporter activity	ATP2A3	IDA		Human	PMID:11956212
Molecular Function	GO:0015085	calcium ion transmembrane transporter activity	ATP2A3	IDA		Human	PMID:15028735
Molecular Function	GO:0015085	calcium ion transmembrane transporter activity	Atp2a3	IDA		Rat	PMID:11956212|RGD:631751
Molecular Function	GO:0030899	calcium-dependent ATPase activity	ATP2A3	IDA		Human	PMID:9843705
Molecular Function	GO:0030899	calcium-dependent ATPase activity	Atp2a3	IDA		Rat	PMID:9843705|RGD:14995324
Molecular Function	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	ATP2A3	IDA		Human	PMID:16725111
Molecular Function	GO:0005388	P-type calcium transporter activity	ATP2A3	IDA		Human	PMID:9843705
Molecular Function	GO:0005388	P-type calcium transporter activity	Atp2a3	IDA		Rat	PMID:9843705|RGD:14995324
Molecular Function	GO:0005515	protein binding	ATP2A3	IPI	UniProtKB:Q96GC9	Human	PMID:28890335
Molecular Function	GO:0005515	protein binding	ATP2A3	IPI	UniProtKB:A0A1B0GTB2	Human	PMID:34513312
Molecular Function	GO:0005515	protein binding	Atp2a3	IPI	PR:Q9CV60	Mouse	PMID:25640239
Molecular Function	GO:0044325	transmembrane transporter binding	ATP2A3	IPI	UniProtKB:P48995	Human	PMID:18068335
Cellular Component	GO:0005783	endoplasmic reticulum	ATP2A3	IDA		Human	PMID:8809064
Cellular Component	GO:0005783	endoplasmic reticulum	Atp2a3	IDA		Mouse	PMID:12119294
Cellular Component	GO:0031090	organelle membrane	ATP2A3	IDA		Human	PMID:15028735
Cellular Component	GO:0016529	sarcoplasmic reticulum	ATP2A3	IDA		Human	PMID:8809064
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ATP2A3	IDA		Human	PMID:16725111
Biological Process	GO:0070588	calcium ion transmembrane transport	ATP2A3	IDA		Human	PMID:11956212
Biological Process	GO:0070588	calcium ion transmembrane transport	ATP2A3	IDA		Human	PMID:9843705
Biological Process	GO:0070588	calcium ion transmembrane transport	Atp2a3	IDA		Rat	PMID:11956212|RGD:631751
Biological Process	GO:0070588	calcium ion transmembrane transport	Atp2a3	IDA		Rat	PMID:9843705|RGD:14995324
Biological Process	GO:1903515	calcium ion transport from cytosol to endoplasmic reticulum	ATP2A3	IDA		Human	PMID:15028735
Biological Process	GO:0032469	endoplasmic reticulum calcium ion homeostasis	Atp2a3	IDA		Rat	PMID:11956212|RGD:631751
Biological Process	GO:0006874	intracellular calcium ion homeostasis	ATP2A3	IMP		Human	PMID:18068335
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	ATP2A3	IDA		Human	PMID:16725111
Biological Process	GO:0097421	liver regeneration	Atp2a3	IEP		Rat	PMID:11032760|RGD:13782137
Biological Process	GO:1900121	negative regulation of receptor binding	ATP2A3	IMP		Human	PMID:18068335

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern