Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATP6AP1
  • Mouse genes Atp6ap1
  • Rat genes Atp6ap1
  • Zfish genes atp6ap1a,atp6ap1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp6ap1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001671	ATPase activator activity	Atp6ap1	IMP		Mouse	PMID:22087256
Molecular Function	GO:0005515	protein binding	ATP6AP1	IPI	UniProtKB:O75787	Human	PMID:29127204
Molecular Function	GO:0005515	protein binding	ATP6AP1	IPI	UniProtKB:P0DTD1:PRO_0000449624	Human	PMID:32353859
Molecular Function	GO:0005515	protein binding	ATP6AP1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP6AP1	IPI	UniProtKB:P0DTD1:PRO_0000449624	Human	PMID:33060197
Molecular Function	GO:0005515	protein binding	ATP6AP1	IPI	UniProtKB:P0DTD1:PRO_0000449624	Human	PMID:33845483
Molecular Function	GO:0005515	protein binding	ATP6AP1	IPI	UniProtKB:P0DTD1:PRO_0000449624	Human	PMID:34232536
Molecular Function	GO:0005515	protein binding	ATP6AP1	IPI	UniProtKB:P0DTD1:PRO_0000449624	Human	PMID:34997207
Molecular Function	GO:0031267	small GTPase binding	Atp6ap1	IPI	UniProtKB:P51150	Mouse	MGI:MGI:5575464|PMID:22467241
Cellular Component	GO:0010008	endosome membrane	Atp6ap1	IMP		Mouse	PMID:22087256
Cellular Component	GO:0070062	extracellular exosome	ATP6AP1	HDA		Human	PMID:19056867
Cellular Component	GO:0016020	membrane	ATP6AP1	IDA		Human	PMID:33065002
Cellular Component	GO:0005886	plasma membrane	atp6ap1b	IDA		Zfish	PMID:26254189
Cellular Component	GO:0030672	synaptic vesicle membrane	Atp6ap1	EXP		Rat	PMID:32165585|RGD:39458019
Cellular Component	GO:0030672	synaptic vesicle membrane	Atp6ap1	IDA		Rat	PMID:32165585|RGD:39458019
Biological Process	GO:0045176	apical protein localization	atp6ap1b	IMP	ZFIN:ZDB-GENO-210928-7	Zfish	PMID:32328632
Biological Process	GO:0036295	cellular response to increased oxygen levels	ATP6AP1	IMP		Human	PMID:28296633
Biological Process	GO:0003140	determination of left/right asymmetry in lateral mesoderm	atp6ap1b	IMP	ZFIN:ZDB-MRPHLNO-160202-1	Zfish	PMID:26254189
Biological Process	GO:0099638	endosome to plasma membrane protein transport	Atp6ap1	IMP		Mouse	MGI:MGI:5575464|PMID:22467241
Biological Process	GO:0008057	eye pigment granule organization	atp6ap1b	IMP	ZFIN:ZDB-GENO-100518-3	Zfish	PMID:18836173
Biological Process	GO:0006879	intracellular iron ion homeostasis	ATP6AP1	IMP		Human	PMID:28296633
Biological Process	GO:0070121	Kupffer's vesicle development	atp6ap1b	IMP	ZFIN:ZDB-MRPHLNO-160202-1	Zfish	PMID:26254189
Biological Process	GO:0032438	melanosome organization	atp6ap1b	IMP	ZFIN:ZDB-GENO-100518-3	Zfish	PMID:18836173
Biological Process	GO:0036035	osteoclast development	Atp6ap1	IMP		Mouse	MGI:MGI:5575464|PMID:22467241
Biological Process	GO:0008104	protein localization	atp6ap1b	IMP	ZFIN:ZDB-MRPHLNO-160202-1	Zfish	PMID:26254189
Biological Process	GO:0072659	protein localization to plasma membrane	atp6ap1b	IMP	ZFIN:ZDB-MRPHLNO-160202-1	Zfish	PMID:26254189
Biological Process	GO:0042127	regulation of cell population proliferation	atp6ap1b	IMP	ZFIN:ZDB-MRPHLNO-160202-1	Zfish	PMID:26254189
Biological Process	GO:0030641	regulation of cellular pH	atp6ap1b	IMP	ZFIN:ZDB-MRPHLNO-160202-1	Zfish	PMID:26254189
Biological Process	GO:1902017	regulation of cilium assembly	atp6ap1b	IMP	ZFIN:ZDB-MRPHLNO-160202-1	Zfish	PMID:26254189
Biological Process	GO:1901207	regulation of heart looping	atp6ap1b	IGI	ZFIN:ZDB-GENE-040718-259	Zfish	PMID:26254189
Biological Process	GO:1901207	regulation of heart looping	atp6ap1b	IMP	ZFIN:ZDB-MRPHLNO-160202-1	Zfish	PMID:26254189
Biological Process	GO:0060041	retina development in camera-type eye	atp6ap1b	IMP	ZFIN:ZDB-GENO-020422-1	Zfish	PMID:15716491
Biological Process	GO:0003406	retinal pigment epithelium development	atp6ap1b	IMP	ZFIN:ZDB-GENO-100518-3	Zfish	PMID:18836173
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6ap1	EXP		Mouse	PMID:28793259
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6ap1	IMP		Mouse	PMID:28793259
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6ap1	IDA		Mouse	PMID:28793259

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern