Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATP6V0A2
  • Mouse genes Atp6v0a2
  • Rat genes
  • Zfish genes atp6v0a2a,atp6v0a2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp6v0a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ATP6V0A2	IPI	UniProtKB:Q99418	Human	PMID:16415858
Molecular Function	GO:0005515	protein binding	Atp6v0a2	IPI	UniProtKB:P63034	Mouse	MGI:MGI:3694285|PMID:16415858
Cellular Component	GO:0001669	acrosomal vesicle	Atp6v0a2	IDA		Mouse	PMID:11872743
Cellular Component	GO:0005925	focal adhesion	ATP6V0A2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ATP6V0A2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043229	intracellular organelle	Atp6v0a2	IDA		Mouse	PMID:12672822
Cellular Component	GO:0005765	lysosomal membrane	ATP6V0A2	HDA		Human	PMID:17897319
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Atp6v0a2	IDA		Mouse	PMID:19549681
Cellular Component	GO:0005886	plasma membrane	ATP6V0A2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0033176	proton-transporting V-type ATPase complex	Atp6v0a2	IDA		Mouse	PMID:12963731
Cellular Component	GO:0033179	proton-transporting V-type ATPase, V0 domain	Atp6v0a2	IDA		Mouse	PMID:11872743
Cellular Component	GO:1902495	transmembrane transporter complex	Atp6v0a2	IDA		Mouse	PMID:12963731
Biological Process	GO:0036295	cellular response to increased oxygen levels	ATP6V0A2	IMP		Human	PMID:28296633
Biological Process	GO:0006879	intracellular iron ion homeostasis	ATP6V0A2	IMP		Human	PMID:28296633

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern