Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATP6V0A4
  • Mouse genes Atp6v0a4
  • Rat genes Atp6v0a4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp6v0a4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	ATP6V0A4	IPI	UniProtKB:O75348	Human	PMID:17360703
Molecular Function	GO:0051117	ATPase binding	ATP6V0A4	IPI	UniProtKB:Q96LB4	Human	PMID:17360703
Molecular Function	GO:0005515	protein binding	ATP6V0A4	IPI	UniProtKB:P00511	Human	PMID:12649290
Molecular Function	GO:0005515	protein binding	ATP6V0A4	IPI	UniProtKB:P08237	Human	PMID:12649290
Molecular Function	GO:0005515	protein binding	ATP6V0A4	IPI	UniProtKB:P00511	Human	PMID:18632794
Molecular Function	GO:0005515	protein binding	ATP6V0A4	IPI	UniProtKB:P47859	Human	PMID:18632794
Molecular Function	GO:0005515	protein binding	ATP6V0A4	IPI	UniProtKB:P02649	Human	PMID:32814053
Cellular Component	GO:0045177	apical part of cell	ATP6V0A4	IDA		Human	PMID:14638902
Cellular Component	GO:0045177	apical part of cell	ATP6V0A4	IDA		Human	PMID:14675051
Cellular Component	GO:0045177	apical part of cell	Atp6v0a4	IDA		Mouse	MGI:MGI:4399029|PMID:14675051
Cellular Component	GO:0045177	apical part of cell	Atp6v0a4	IDA		Mouse	PMID:11495928
Cellular Component	GO:0045177	apical part of cell	Atp6v0a4	IDA		Rat	PMID:16192400|RGD:1581809
Cellular Component	GO:0016324	apical plasma membrane	ATP6V0A4	IDA		Human	PMID:10973252
Cellular Component	GO:0016324	apical plasma membrane	ATP6V0A4	IDA		Human	PMID:12649290
Cellular Component	GO:0016324	apical plasma membrane	ATP6V0A4	IDA		Human	PMID:15800125
Cellular Component	GO:0016324	apical plasma membrane	Atp6v0a4	IDA		Mouse	MGI:MGI:3850618|PMID:16177003
Cellular Component	GO:0016324	apical plasma membrane	Atp6v0a4	IDA		Mouse	MGI:MGI:3850621|PMID:15385584
Cellular Component	GO:0016324	apical plasma membrane	Atp6v0a4	IDA		Rat	PMID:16352747|RGD:8553330
Cellular Component	GO:0016324	apical plasma membrane	Atp6v0a4	IDA		Rat	PMID:17804457|RGD:8554499
Cellular Component	GO:0005903	brush border	Atp6v0a4	IDA		Mouse	PMID:11495928
Cellular Component	GO:0031526	brush border membrane	ATP6V0A4	IDA		Human	PMID:14638902
Cellular Component	GO:0005768	endosome	Atp6v0a4	IDA		Mouse	MGI:MGI:3850618|PMID:16177003
Cellular Component	GO:0070062	extracellular exosome	ATP6V0A4	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ATP6V0A4	HDA		Human	PMID:19199708
Cellular Component	GO:0005765	lysosomal membrane	ATP6V0A4	HDA		Human	PMID:17897319
Cellular Component	GO:0005886	plasma membrane	ATP6V0A4	IDA		Human	PMID:17360703
Cellular Component	GO:0030672	synaptic vesicle membrane	Atp6v0a4	EXP		Rat	PMID:23622064|RGD:13702180
Cellular Component	GO:0030672	synaptic vesicle membrane	Atp6v0a4	IDA		Rat	PMID:23622064|RGD:13702180
Cellular Component	GO:0016471	vacuolar proton-transporting V-type ATPase complex	ATP6V0A4	IDA		Human	PMID:10973252
Cellular Component	GO:0016471	vacuolar proton-transporting V-type ATPase complex	Atp6v0a4	IPI	MGI:MGI:2151814	Mouse	PMID:11498539
Biological Process	GO:0001503	ossification	ATP6V0A4	IMP		Human	PMID:10973252
Biological Process	GO:1902600	proton transmembrane transport	ATP6V0A4	IMP		Human	PMID:10973252
Biological Process	GO:1902600	proton transmembrane transport	Atp6v0a4	IPI	MGI:MGI:2151814	Mouse	PMID:11498539
Biological Process	GO:0006885	regulation of pH	ATP6V0A4	IMP		Human	PMID:10973252
Biological Process	GO:0097254	renal tubular secretion	ATP6V0A4	IMP		Human	PMID:12414817
Biological Process	GO:0007605	sensory perception of sound	ATP6V0A4	IMP		Human	PMID:12414817
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6v0a4	IDA		Mouse	PMID:28793259
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6v0a4	EXP		Mouse	PMID:28793259
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6v0a4	IMP		Mouse	PMID:28793259

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern