Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATP6V1B2
  • Mouse genes Atp6v1b2
  • Rat genes Atp6v1b2
  • Zfish genes atp6v1b2,atp6v1ba
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp6v1b2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ATP6V1B2	IPI	UniProtKB:P15884	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ATP6V1B2	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP6V1B2	IPI	UniProtKB:P07196	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP6V1B2	IPI	UniProtKB:P14136	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP6V1B2	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP6V1B2	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP6V1B2	IPI	UniProtKB:Q9Y3C5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ATP6V1B2	IPI	UniProtKB:P0DTD1:PRO_0000449620	Human	PMID:34159380
Cellular Component	GO:0016324	apical plasma membrane	ATP6V1B2	IDA		Human	PMID:29993276
Cellular Component	GO:0016324	apical plasma membrane	Atp6v1b2	IDA		Mouse	MGI:MGI:6381273|PMID:29993276
Cellular Component	GO:0016324	apical plasma membrane	Atp6v1b2	IDA		Mouse	PMID:22245629
Cellular Component	GO:0005737	cytoplasm	Atp6v1b2	IDA		Mouse	MGI:MGI:3760063|PMID:17392376
Cellular Component	GO:0005829	cytosol	Atp6v1b2	IDA		Mouse	MGI:MGI:4943394|PMID:17898041
Cellular Component	GO:0005829	cytosol	Atp6v1b2	IDA		Mouse	MGI:MGI:3850618|PMID:16177003
Cellular Component	GO:0070062	extracellular exosome	ATP6V1B2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ATP6V1B2	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	ATP6V1B2	HDA		Human	PMID:23533145
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Atp6v1b2	EXP		Rat	PMID:32165585|RGD:39458019
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Atp6v1b2	IDA		Rat	PMID:32165585|RGD:39458019
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ATP6V1B2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005765	lysosomal membrane	ATP6V1B2	HDA		Human	PMID:17897319
Cellular Component	GO:0016020	membrane	Atp6v1b2	IDA		Rat	PMID:15013950|RGD:1304309
Cellular Component	GO:0005902	microvillus	Atp6v1b2	IDA		Mouse	MGI:MGI:4943380|PMID:18667600
Cellular Component	GO:0005902	microvillus	Atp6v1b2	IDA		Mouse	MGI:MGI:4943394|PMID:17898041
Cellular Component	GO:0043209	myelin sheath	Atp6v1b2	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0005886	plasma membrane	Atp6v1b2	IDA		Mouse	MGI:MGI:3850618|PMID:16177003
Cellular Component	GO:0001726	ruffle	Atp6v1b2	IDA		Mouse	MGI:MGI:5575464|PMID:22467241
Cellular Component	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain	ATP6V1B2	IDA		Human	PMID:33065002
Cellular Component	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain	Atp6v1b2	IDA		Rat	PMID:32165585|RGD:39458019
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6v1b2	IMP		Mouse	PMID:28793259
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6v1b2	EXP		Mouse	PMID:28793259
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6v1b2	IDA		Mouse	PMID:28793259

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern