Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATP6V1E1
  • Mouse genes Atp6v1e1
  • Rat genes Atp6v1e1
  • Zfish genes atp6v1e1a,atp6v1e1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp6v1e1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	ATP6V1E1	IPI	UniProtKB:Q15907	Human	PMID:20717956
Molecular Function	GO:0005515	protein binding	ATP6V1E1	IPI	UniProtKB:P09972	Human	PMID:11399750
Molecular Function	GO:0005515	protein binding	ATP6V1E1	IPI	UniProtKB:P26651	Human	PMID:21784977
Molecular Function	GO:0005515	protein binding	Atp6v1e1	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:0015078	proton transmembrane transporter activity	atp6v1e1b	IDA		Zfish	PMID:24671205
Molecular Function	GO:0046961	proton-transporting ATPase activity, rotational mechanism	Atp6v1e1	IGI	SGD:S000005859	Mouse	PMID:11872743
Cellular Component	GO:0016324	apical plasma membrane	Atp6v1e1	IDA		Mouse	MGI:MGI:4943380|PMID:18667600
Cellular Component	GO:0016324	apical plasma membrane	Atp6v1e1	IDA		Mouse	MGI:MGI:3850618|PMID:16177003
Cellular Component	GO:0016324	apical plasma membrane	Atp6v1e1	IDA		Mouse	PMID:11423561
Cellular Component	GO:0005737	cytoplasm	Atp6v1e1	IDA		Mouse	PMID:11872743
Cellular Component	GO:0005829	cytosol	Atp6v1e1	IDA		Mouse	MGI:MGI:3850618|PMID:16177003
Cellular Component	GO:0005768	endosome	Atp6v1e1	IDA		Mouse	MGI:MGI:3850618|PMID:16177003
Cellular Component	GO:0070062	extracellular exosome	ATP6V1E1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ATP6V1E1	HDA		Human	PMID:19199708
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Atp6v1e1	EXP		Rat	PMID:32165585|RGD:39458019
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Atp6v1e1	IDA		Rat	PMID:32165585|RGD:39458019
Cellular Component	GO:0005765	lysosomal membrane	ATP6V1E1	HDA		Human	PMID:17897319
Cellular Component	GO:0005902	microvillus	Atp6v1e1	IDA		Mouse	MGI:MGI:4943380|PMID:18667600
Cellular Component	GO:0005739	mitochondrion	Atp6v1e1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain	ATP6V1E1	IDA		Human	PMID:33065002
Cellular Component	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain	Atp6v1e1	IDA		Rat	PMID:32165585|RGD:39458019
Biological Process	GO:0033336	caudal fin development	atp6v1e1b	IMP	ZFIN:ZDB-GENO-100415-1	Zfish	PMID:24671205
Biological Process	GO:0031101	fin regeneration	atp6v1e1b	IMP	ZFIN:ZDB-MRPHLNO-140911-3	Zfish	PMID:24671205
Biological Process	GO:0060036	notochord cell vacuolation	atp6v1e1b	IMP	ZFIN:ZDB-GENO-100415-1	Zfish	PMID:23460678
Biological Process	GO:1902600	proton transmembrane transport	Atp6v1e1	IGI	SGD:S000005859	Mouse	PMID:11872743
Biological Process	GO:0060041	retina development in camera-type eye	atp6v1e1b	IMP	ZFIN:ZDB-GENO-020430-4	Zfish	PMID:15716491
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6v1e1	IMP		Mouse	PMID:28793259
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6v1e1	IDA		Mouse	PMID:28793259
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6v1e1	EXP		Mouse	PMID:28793259

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern