Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Atp7a

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ATP7A
- Mouse genes Atp7a
- Rat genes Atp7a
- Zfish genes atp7a
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp7a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	ATP7A	IDA		Human	PMID:19917612
Molecular Function	GO:0005507	copper ion binding	ATP7A	IDA		Human	PMID:15670166
Molecular Function	GO:0005375	copper ion transmembrane transporter activity	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:10332039
Molecular Function	GO:0005375	copper ion transmembrane transporter activity	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:10332039
Molecular Function	GO:0032767	copper-dependent protein binding	ATP7A	IPI	UniProtKB:O00244	Human	PMID:10497213
Molecular Function	GO:0032767	copper-dependent protein binding	ATP7A	IDA		Human	PMID:31283225
Molecular Function	GO:1903136	cuprous ion binding	ATP7A	IMP		Human	PMID:14572476
Molecular Function	GO:1903136	cuprous ion binding	ATP7A	IMP		Human	PMID:15035611
Molecular Function	GO:1903136	cuprous ion binding	ATP7A	IDA		Human	PMID:31283225
Molecular Function	GO:0043682	P-type divalent copper transporter activity	Atp7a	IDA		Mouse	PMID:15634671
Molecular Function	GO:0140581	P-type monovalent copper transporter activity	ATP7A	IDA		Human	PMID:10419525
Molecular Function	GO:0005515	protein binding	ATP7A	IPI	UniProtKB:Q5EBL8	Human	PMID:16051599
Molecular Function	GO:0005515	protein binding	ATP7A	IPI	UniProtKB:P08294	Human	PMID:16371425
Molecular Function	GO:0005515	protein binding	ATP7A	IPI	UniProtKB:P35754	Human	PMID:16884690
Molecular Function	GO:0005515	protein binding	ATP7A	IPI	UniProtKB:O00244	Human	PMID:21667063
Molecular Function	GO:0005515	protein binding	ATP7A	IPI	UniProtKB:Q8N668	Human	PMID:21667063
Molecular Function	GO:0005515	protein binding	ATP7A	IPI	UniProtKB:Q96L92	Human	PMID:23563491
Molecular Function	GO:0005515	protein binding	ATP7A	IPI	UniProtKB:P09172	Human	PMID:26199316
Molecular Function	GO:0005515	protein binding	Atp7a	IPI	UniProtKB:P07147	Mouse	MGI:MGI:3807110\|PMID:18650808
Molecular Function	GO:0005515	protein binding	Atp7a	IPI	PR:O09164	Mouse	PMID:16371425
Molecular Function	GO:0051087	protein-folding chaperone binding	Atp7a	IPI	RGD:621684	Rat	PMID:23349186\|RGD:11341699
Molecular Function	GO:0031267	small GTPase binding	Atp7a	IPI	RGD:619755	Rat	PMID:20671235\|RGD:11341707
Molecular Function	GO:0016532	superoxide dismutase copper chaperone activity	Atp7a	IDA		Mouse	PMID:16371425
Cellular Component	GO:0016324	apical plasma membrane	Atp7a	IDA		Rat	PMID:16081413\|RGD:1581810
Cellular Component	GO:0016324	apical plasma membrane	Atp7a	IDA		Rat	PMID:16741141\|RGD:1599391
Cellular Component	GO:0030424	axon	Atp7a	IDA		Rat	PMID:15634787\|RGD:8553777
Cellular Component	GO:0016323	basolateral plasma membrane	ATP7A	IDA		Human	PMID:16397091
Cellular Component	GO:0016323	basolateral plasma membrane	Atp7a	IDA		Rat	PMID:16081413\|RGD:1581810
Cellular Component	GO:0031526	brush border membrane	Atp7a	IDA		Rat	PMID:16081413\|RGD:1581810
Cellular Component	GO:0031252	cell leading edge	Atp7a	IDA		Rat	PMID:23349186\|RGD:11341699
Cellular Component	GO:0031410	cytoplasmic vesicle	Atp7a	IDA		Mouse	PMID:17003121
Cellular Component	GO:0031410	cytoplasmic vesicle	Atp7a	IDA		Mouse	PMID:15634787
Cellular Component	GO:0005829	cytosol	Atp7a	IDA		Rat	PMID:19679821\|RGD:11341808
Cellular Component	GO:0030425	dendrite	Atp7a	IDA		Rat	PMID:15634787\|RGD:8553777
Cellular Component	GO:0031901	early endosome membrane	Atp7a	IDA		Mouse	MGI:MGI:6508511\|PMID:27337370
Cellular Component	GO:0005794	Golgi apparatus	ATP7A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	ATP7A	IDA		Human	PMID:9467005
Cellular Component	GO:0005794	Golgi apparatus	Atp7a	IDA		Mouse	PMID:15634787
Cellular Component	GO:0005794	Golgi apparatus	Atp7a	IDA		Rat	PMID:15634787\|RGD:8553777
Cellular Component	GO:0005794	Golgi apparatus	Atp7a	IDA		Rat	PMID:26170456\|RGD:11341666
Cellular Component	GO:0005770	late endosome	ATP7A	IDA		Human	PMID:8943055
Cellular Component	GO:0005770	late endosome	Atp7a	IDA		Rat	PMID:16741141\|RGD:1599391
Cellular Component	GO:0033162	melanosome membrane	Atp7a	IDA		Mouse	MGI:MGI:3807110\|PMID:18650808
Cellular Component	GO:0016020	membrane	ATP7A	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Atp7a	IDA		Mouse	PMID:15634671
Cellular Component	GO:0016020	membrane	Atp7a	IDA		Mouse	PMID:9215672
Cellular Component	GO:0016020	membrane	Atp7a	IDA		Rat	PMID:12488345\|RGD:8554046
Cellular Component	GO:0045121	membrane raft	Atp7a	IDA		Rat	PMID:20671235\|RGD:11341707
Cellular Component	GO:0005902	microvillus	Atp7a	IDA		Rat	PMID:24614235\|RGD:11341682
Cellular Component	GO:0043005	neuron projection	Atp7a	IDA		Mouse	PMID:15634787
Cellular Component	GO:0043025	neuronal cell body	Atp7a	IDA		Mouse	PMID:15634671
Cellular Component	GO:0005634	nucleus	Atp7a	IDA		Rat	PMID:19679821\|RGD:11341808
Cellular Component	GO:0043204	perikaryon	Atp7a	IDA		Rat	PMID:20836889\|RGD:11341706
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ATP7A	IDA		Human	PMID:10567439
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ATP7A	IDA		Human	PMID:16397091
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ATP7A	IDA		Human	PMID:8943055
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Atp7a	IDA		Rat	PMID:17158254\|RGD:1599385
Cellular Component	GO:0005886	plasma membrane	ATP7A	IDA		Human	PMID:12812980
Cellular Component	GO:0005886	plasma membrane	Atp7a	IDA		Mouse	MGI:MGI:6508511\|PMID:27337370
Cellular Component	GO:0005886	plasma membrane	Atp7a	IDA		Mouse	PMID:10332039
Cellular Component	GO:0005886	plasma membrane	Atp7a	IDA		Rat	PMID:25156967\|RGD:11341673
Cellular Component	GO:0030141	secretory granule	Atp7a	IDA		Rat	PMID:16185750\|RGD:1581811
Cellular Component	GO:0005802	trans-Golgi network	ATP7A	IDA		Human	PMID:12812980
Cellular Component	GO:0005802	trans-Golgi network	ATP7A	IDA		Human	PMID:8943055
Cellular Component	GO:0005802	trans-Golgi network	Atp7a	IDA		Mouse	PMID:16371425
Cellular Component	GO:0005802	trans-Golgi network	Atp7a	IDA		Mouse	PMID:12488345
Cellular Component	GO:0005802	trans-Golgi network	Atp7a	IDA		Mouse	PMID:10332039
Cellular Component	GO:0005802	trans-Golgi network	Atp7a	IDA		Mouse	PMID:17003121
Cellular Component	GO:0005802	trans-Golgi network	Atp7a	IDA		Rat	PMID:12488345\|RGD:8554046
Cellular Component	GO:0005802	trans-Golgi network	Atp7a	IDA		Rat	PMID:16185750\|RGD:1581811
Cellular Component	GO:0005802	trans-Golgi network	Atp7a	IDA		Rat	PMID:20671235\|RGD:11341707
Cellular Component	GO:0032588	trans-Golgi network membrane	Atp7a	IDA		Mouse	MGI:MGI:6508511\|PMID:27337370
Cellular Component	GO:0032588	trans-Golgi network membrane	Atp7a	IDA		Mouse	MGI:MGI:3807110\|PMID:18650808
Cellular Component	GO:0032588	trans-Golgi network membrane	Atp7a	IDA		Rat	PMID:15634787\|RGD:8553777
Cellular Component	GO:0030140	trans-Golgi network transport vesicle	ATP7A	IMP		Human	PMID:9817923
Biological Process	GO:0046034	ATP metabolic process	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:11311799
Biological Process	GO:0001568	blood vessel development	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:1115218
Biological Process	GO:0001568	blood vessel development	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:10632785
Biological Process	GO:0001568	blood vessel development	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:3385878
Biological Process	GO:0001974	blood vessel remodeling	Atp7a	IMP	MGI:MGI:3588774	Mouse	PMID:16338116
Biological Process	GO:0051216	cartilage development	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:8895222
Biological Process	GO:0006584	catecholamine metabolic process	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:17511
Biological Process	GO:0071230	cellular response to amino acid stimulus	Atp7a	IMP		Rat	PMID:26722473\|RGD:11341663
Biological Process	GO:0071236	cellular response to antibiotic	Atp7a	IEP		Rat	PMID:23814049\|RGD:11341692
Biological Process	GO:0071276	cellular response to cadmium ion	Atp7a	IEP		Rat	PMID:17584760\|RGD:8655656
Biological Process	GO:0071279	cellular response to cobalt ion	Atp7a	IEP		Rat	PMID:23814049\|RGD:11341692
Biological Process	GO:0071280	cellular response to copper ion	Atp7a	IDA		Rat	PMID:20671235\|RGD:11341707
Biological Process	GO:0071280	cellular response to copper ion	Atp7a	IEP		Rat	PMID:23174565\|RGD:11341702
Biological Process	GO:0071456	cellular response to hypoxia	Atp7a	IEP		Rat	PMID:21346155\|RGD:11341705
Biological Process	GO:0071281	cellular response to iron ion	Atp7a	IEP		Rat	PMID:19679821\|RGD:11341808
Biological Process	GO:0071281	cellular response to iron ion	Atp7a	IEP		Rat	PMID:23174565\|RGD:11341702
Biological Process	GO:0071284	cellular response to lead ion	Atp7a	IEP		Rat	PMID:24316150\|RGD:11341684
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	Atp7a	IMP		Rat	PMID:20671235\|RGD:11341707
Biological Process	GO:0021954	central nervous system neuron development	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:8174230
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	Atp7a	IMP	MGI:MGI:1856466	Mouse	PMID:2473662
Biological Process	GO:0030199	collagen fibril organization	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:20889
Biological Process	GO:0030199	collagen fibril organization	Atp7a	IMP	MGI:MGI:1856101	Mouse	PMID:8096378
Biological Process	GO:0030199	collagen fibril organization	Atp7a	IMP	MGI:MGI:1856102	Mouse	PMID:4808708
Biological Process	GO:0030199	collagen fibril organization	Atp7a	IMP	MGI:MGI:3588774	Mouse	PMID:16338116
Biological Process	GO:0030199	collagen fibril organization	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:8895222
Biological Process	GO:0060003	copper ion export	ATP7A	IDA		Human	PMID:10419525
Biological Process	GO:0060003	copper ion export	Atp7a	IMP		Mouse	MGI:MGI:3574155\|PMID:15634787
Biological Process	GO:0060003	copper ion export	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:6542992
Biological Process	GO:0060003	copper ion export	Atp7a	IMP		Rat	PMID:22442359\|RGD:8554868
Biological Process	GO:0060003	copper ion export	Atp7a	IMP		Rat	PMID:26722473\|RGD:11341663
Biological Process	GO:0015677	copper ion import	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:573619
Biological Process	GO:0015677	copper ion import	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:7197928
Biological Process	GO:0015677	copper ion import	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:573617
Biological Process	GO:0015677	copper ion import	Atp7a	IMP	MGI:MGI:1856100	Mouse	MGI:MGI:63033
Biological Process	GO:0006825	copper ion transport	ATP7A	IMP		Human	PMID:11092760
Biological Process	GO:0006825	copper ion transport	Atp7a	IDA		Mouse	PMID:15634671
Biological Process	GO:0006825	copper ion transport	Atp7a	IMP		Mouse	PMID:11391006
Biological Process	GO:0048813	dendrite morphogenesis	Atp7a	IMP	MGI:MGI:1856466	Mouse	PMID:2473662
Biological Process	GO:0010273	detoxification of copper ion	Atp7a	IMP	MGI:MGI:1856466	Mouse	PMID:7509170
Biological Process	GO:0042417	dopamine metabolic process	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:8174230
Biological Process	GO:0042417	dopamine metabolic process	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:1752214
Biological Process	GO:0042417	dopamine metabolic process	Atp7a	IMP	MGI:MGI:1856466	Mouse	MGI:MGI:71923
Biological Process	GO:0048251	elastic fiber assembly	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:3385878
Biological Process	GO:0048251	elastic fiber assembly	Atp7a	IMP	MGI:MGI:3588774	Mouse	PMID:16338116
Biological Process	GO:0048251	elastic fiber assembly	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:937819
Biological Process	GO:0048251	elastic fiber assembly	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:20889
Biological Process	GO:0051542	elastin biosynthetic process	Atp7a	IMP	MGI:MGI:1856101	Mouse	PMID:8096378
Biological Process	GO:0042414	epinephrine metabolic process	Atp7a	IMP	MGI:MGI:1856466	Mouse	MGI:MGI:71923
Biological Process	GO:0042414	epinephrine metabolic process	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:1752214
Biological Process	GO:0051649	establishment of localization in cell	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:6542992
Biological Process	GO:0030198	extracellular matrix organization	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:1115218
Biological Process	GO:0007565	female pregnancy	Atp7a	IEP		Rat	PMID:28089327\|RGD:25671605
Biological Process	GO:0031069	hair follicle morphogenesis	Atp7a	IMP	MGI:MGI:1856099	Mouse	MGI:MGI:61157
Biological Process	GO:0031069	hair follicle morphogenesis	Atp7a	IMP	MGI:MGI:1856466	Mouse	PMID:2473662
Biological Process	GO:0035137	hindlimb morphogenesis	Atp7a	IMP	MGI:MGI:1856099	Mouse	MGI:MGI:61157
Biological Process	GO:0001701	in utero embryonic development	Atp7a	IEP		Rat	PMID:10864443\|RGD:1599395
Biological Process	GO:0006878	intracellular copper ion homeostasis	ATP7A	IMP		Human	PMID:16397091
Biological Process	GO:0006878	intracellular copper ion homeostasis	ATP7A	IMP		Human	PMID:28389643
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP		Mouse	MGI:MGI:5637881\|PMID:25639447
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:4858102
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856466	Mouse	PMID:9686356
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:11311799
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856466	Mouse	MGI:MGI:60964
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:3674914
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1858103	Mouse	PMID:9321757
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:571898
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:7197928
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856466	Mouse	PMID:7873696
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:564942
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856099	Mouse	PMID:9321757
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IGI	MGI:MGI:97172	Mouse	PMID:8640230
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:573619
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:573617
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:9321757
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:27591
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856101	Mouse	PMID:8096378
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:187892
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856098	Mouse	MGI:MGI:61151
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856322	Mouse	PMID:9321757
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856466	Mouse	PMID:1779648
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:10332039
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856324	Mouse	PMID:9321757
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:3588774	Mouse	PMID:16338116
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:9321757
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:8025644
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856101	Mouse	PMID:9321757
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:6685755
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IGI	MGI:MGI:97171	Mouse	PMID:8640230
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:187892
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856325	Mouse	PMID:9321757
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856466	Mouse	PMID:7688531
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856323	Mouse	PMID:9321757
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:10332039
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7a	IMP	MGI:MGI:1856466	Mouse	MGI:MGI:63873
Biological Process	GO:0007595	lactation	Atp7a	IEP		Rat	PMID:16741141\|RGD:1599391
Biological Process	GO:0001889	liver development	Atp7a	IEP		Rat	PMID:25349135\|RGD:11341669
Biological Process	GO:0007626	locomotory behavior	Atp7a	IMP	MGI:MGI:1856466	Mouse	PMID:2473662
Biological Process	GO:0007626	locomotory behavior	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:1752214
Biological Process	GO:0007626	locomotory behavior	Atp7a	IMP	MGI:MGI:3588774	Mouse	PMID:16338116
Biological Process	GO:0048286	lung alveolus development	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:937819
Biological Process	GO:0007005	mitochondrion organization	Atp7a	IMP	MGI:MGI:1856466	Mouse	PMID:8009964
Biological Process	GO:0007005	mitochondrion organization	Atp7a	IMP	MGI:MGI:1856466	Mouse	PMID:2288383
Biological Process	GO:0045914	negative regulation of catecholamine metabolic process	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:17511
Biological Process	GO:0034760	negative regulation of iron ion transmembrane transport	Atp7a	IMP		Rat	PMID:24174620\|RGD:11341686
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:17003121
Biological Process	GO:0051402	neuron apoptotic process	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:17003121
Biological Process	GO:0070050	neuron cellular homeostasis	Atp7a	IMP	MGI:MGI:1856466	Mouse	PMID:9686356
Biological Process	GO:0048812	neuron projection morphogenesis	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:8174230
Biological Process	GO:0042421	norepinephrine biosynthetic process	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:4858102
Biological Process	GO:0042421	norepinephrine biosynthetic process	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:4405722
Biological Process	GO:0042415	norepinephrine metabolic process	Atp7a	IMP	MGI:MGI:1856466	Mouse	MGI:MGI:71923
Biological Process	GO:0042415	norepinephrine metabolic process	Atp7a	IMP	MGI:MGI:1856102	Mouse	PMID:4147174
Biological Process	GO:0018205	peptidyl-lysine modification	Atp7a	IMP	MGI:MGI:1856102	Mouse	PMID:4808708
Biological Process	GO:0043473	pigmentation	Atp7a	IMP	MGI:MGI:1856466	Mouse	PMID:2473662
Biological Process	GO:0043473	pigmentation	Atp7a	IMP	MGI:MGI:3588774	Mouse	PMID:16338116
Biological Process	GO:0043473	pigmentation	Atp7a	IMP	MGI:MGI:1856099	Mouse	MGI:MGI:61157
Biological Process	GO:0043473	pigmentation	Atp7a	IMP	MGI:MGI:1856100	Mouse	MGI:MGI:63033
Biological Process	GO:0043473	pigmentation	Atp7a	IMP	MGI:MGI:1856479	Mouse	MGI:MGI:63057
Biological Process	GO:0043473	pigmentation	Atp7a	IMP	MGI:MGI:1856323	Mouse	MGI:MGI:64387
Biological Process	GO:0043473	pigmentation	Atp7a	IMP	MGI:MGI:2447843	Mouse	MGI:MGI:61313
Biological Process	GO:0043473	pigmentation	Atp7a	IMP	MGI:MGI:1856101	Mouse	MGI:MGI:72704
Biological Process	GO:0043473	pigmentation	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:4858102
Biological Process	GO:0043473	pigmentation	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:1752214
Biological Process	GO:0043473	pigmentation	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:4670054
Biological Process	GO:0043473	pigmentation	Atp7a	IMP	MGI:MGI:1856099	Mouse	PMID:4561716
Biological Process	GO:0043473	pigmentation	Atp7a	IMP	MGI:MGI:1856098	Mouse	MGI:MGI:61250
Biological Process	GO:0043473	pigmentation	Atp7a	IMP	MGI:MGI:1856324	Mouse	MGI:MGI:64387
Biological Process	GO:0043473	pigmentation	Atp7a	IMP	MGI:MGI:1856322	Mouse	MGI:MGI:64387
Biological Process	GO:0043473	pigmentation	Atp7a	IMP	MGI:MGI:1856096	Mouse	MGI:MGI:61250
Biological Process	GO:0043085	positive regulation of catalytic activity	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:16371425
Biological Process	GO:0043085	positive regulation of catalytic activity	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:14140
Biological Process	GO:0043085	positive regulation of catalytic activity	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:20889
Biological Process	GO:0043085	positive regulation of catalytic activity	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:12488345
Biological Process	GO:0043085	positive regulation of catalytic activity	Atp7a	IMP	MGI:MGI:1856101	Mouse	PMID:8096378
Biological Process	GO:0045793	positive regulation of cell size	Atp7a	IMP		Rat	PMID:26722473\|RGD:11341663
Biological Process	GO:1904960	positive regulation of cytochrome-c oxidase activity	Atp7a	IMP	MGI:MGI:1856466	Mouse	MGI:MGI:60964
Biological Process	GO:1904960	positive regulation of cytochrome-c oxidase activity	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:17511
Biological Process	GO:1904960	positive regulation of cytochrome-c oxidase activity	Atp7a	IMP	MGI:MGI:1856102	Mouse	PMID:10098864
Biological Process	GO:1904960	positive regulation of cytochrome-c oxidase activity	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:11311799
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Atp7a	IMP		Rat	PMID:25156967\|RGD:11341673
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	Atp7a	IMP		Rat	PMID:20671235\|RGD:11341707
Biological Process	GO:0048023	positive regulation of melanin biosynthetic process	ATP7A	IMP		Human	PMID:11092760
Biological Process	GO:1903036	positive regulation of response to wounding	Atp7a	IMP		Rat	PMID:20671235\|RGD:11341707
Biological Process	GO:1901671	positive regulation of superoxide dismutase activity	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:17511
Biological Process	GO:0032773	positive regulation of tyrosinase activity	ATP7A	IMP		Human	PMID:11092760
Biological Process	GO:1904754	positive regulation of vascular associated smooth muscle cell migration	Atp7a	IMP		Rat	PMID:20671235\|RGD:11341707
Biological Process	GO:0021860	pyramidal neuron development	Atp7a	IMP	MGI:MGI:1856466	Mouse	PMID:2473662
Biological Process	GO:1904959	regulation of cytochrome-c oxidase activity	Atp7a	IMP		Rat	PMID:26722473\|RGD:11341663
Biological Process	GO:0010468	regulation of gene expression	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:11311799
Biological Process	GO:0010468	regulation of gene expression	Atp7a	IMP		Rat	PMID:25156967\|RGD:11341673
Biological Process	GO:0002082	regulation of oxidative phosphorylation	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:8550574
Biological Process	GO:0001836	release of cytochrome c from mitochondria	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:11311799
Biological Process	GO:0019430	removal of superoxide radicals	Atp7a	IMP	MGI:MGI:1856097	Mouse	PMID:16371425
Biological Process	GO:0046688	response to copper ion	Atp7a	IEP		Rat	PMID:15591161\|RGD:1599393
Biological Process	GO:0046688	response to copper ion	Atp7a	IDA		Rat	PMID:17158254\|RGD:1599385
Biological Process	GO:0046688	response to copper ion	atp7a	IMP	ZFIN:ZDB-GENO-061215-1,ZFIN:ZDB-MRPHLNO-061215-4,ZFIN:ZDB-MRPHLNO-061215-5	Zfish	PMID:16890543
Biological Process	GO:0046688	response to copper ion	atp7a	IDA		Zfish	PMID:18987288
Biological Process	GO:0046688	response to copper ion	atp7a	IMP	ZFIN:ZDB-GENO-090213-1	Zfish	PMID:19008952
Biological Process	GO:0010041	response to iron(III) ion	Atp7a	IEP		Rat	PMID:16629162\|RGD:1599392
Biological Process	GO:0010288	response to lead ion	Atp7a	IEP		Rat	PMID:25579025\|RGD:11341668
Biological Process	GO:0010042	response to manganese ion	Atp7a	IDA		Rat	PMID:24614235\|RGD:11341682
Biological Process	GO:0010042	response to manganese ion	Atp7a	IEP		Rat	PMID:24614235\|RGD:11341682
Biological Process	GO:0010038	response to metal ion	atp7a	IDA		Zfish	PMID:18987288
Biological Process	GO:0010043	response to zinc ion	Atp7a	IEP		Rat	PMID:12840169\|RGD:1599394
Biological Process	GO:0042428	serotonin metabolic process	Atp7a	IMP	MGI:MGI:1856098	Mouse	PMID:8174230
Biological Process	GO:0043588	skin development	Atp7a	IMP	MGI:MGI:1856102	Mouse	PMID:4808708
Biological Process	GO:0042093	T-helper cell differentiation	Atp7a	IMP	MGI:MGI:1856466	Mouse	PMID:8434133
Biological Process	GO:0006568	tryptophan metabolic process	Atp7a	IMP	MGI:MGI:1856102	Mouse	PMID:4147174
Biological Process	GO:0006570	tyrosine metabolic process	Atp7a	IMP	MGI:MGI:1856102	Mouse	PMID:4147174

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.