Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Atp7b

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ATP7B
- Mouse genes Atp7b
- Rat genes Atp7b
- Zfish genes atp7b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp7b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	ATP7B	IDA		Human	PMID:15205462
Molecular Function	GO:0005524	ATP binding	ATP7B	IDA		Human	PMID:16567646
Molecular Function	GO:0005507	copper ion binding	ATP7B	IDA		Human	PMID:12029094
Molecular Function	GO:0005507	copper ion binding	ATP7B	IDA		Human	PMID:14709553
Molecular Function	GO:0005507	copper ion binding	Atp7b	IDA		Rat	PMID:14732483\|RGD:1581812
Molecular Function	GO:0005375	copper ion transmembrane transporter activity	ATP7B	IDA		Human	PMID:26004889
Molecular Function	GO:0005375	copper ion transmembrane transporter activity	Atp7b	IDA		Rat	PMID:9920665\|RGD:1599396
Molecular Function	GO:0043682	P-type divalent copper transporter activity	ATP7B	IMP		Human	PMID:9837819
Molecular Function	GO:0043682	P-type divalent copper transporter activity	Atp7b	IDA		Mouse	PMID:11237756
Molecular Function	GO:0043682	P-type divalent copper transporter activity	Atp7b	IDA		Mouse	PMID:15634671
Molecular Function	GO:0043682	P-type divalent copper transporter activity	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:11237756
Molecular Function	GO:0005515	protein binding	ATP7B	IPI	UniProtKB:O00244	Human	PMID:12968035
Molecular Function	GO:0005515	protein binding	ATP7B	IPI	UniProtKB:Q8N668	Human	PMID:12968035
Molecular Function	GO:0005515	protein binding	ATP7B	IPI	UniProtKB:Q9UJW0	Human	PMID:16554302
Molecular Function	GO:0005515	protein binding	ATP7B	IPI	UniProtKB:Q05516	Human	PMID:16676348
Molecular Function	GO:0005515	protein binding	ATP7B	IPI	UniProtKB:P35754	Human	PMID:16884690
Molecular Function	GO:0005515	protein binding	ATP7B	IPI	UniProtKB:Q8N668	Human	PMID:17919502
Molecular Function	GO:0008270	zinc ion binding	Atp7b	IDA		Rat	PMID:14732483\|RGD:1581812
Cellular Component	GO:0045177	apical part of cell	Atp7b	IDA		Rat	PMID:15994426\|RGD:1581816
Cellular Component	GO:0016323	basolateral plasma membrane	ATP7B	IDA		Human	PMID:15269005
Cellular Component	GO:0016323	basolateral plasma membrane	Atp7b	IDA		Rat	PMID:24614235\|RGD:11341682
Cellular Component	GO:0005923	bicellular tight junction	Atp7b	IDA		Rat	PMID:18395099\|RGD:2292671
Cellular Component	GO:0031410	cytoplasmic vesicle	ATP7B	IDA		Human	PMID:16472602
Cellular Component	GO:0005783	endoplasmic reticulum	Atp7b	IDA		Rat	PMID:16741141\|RGD:1599391
Cellular Component	GO:0005794	Golgi apparatus	ATP7B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005770	late endosome	ATP7B	IDA		Human	PMID:15681833
Cellular Component	GO:0005770	late endosome	Atp7b	IDA		Rat	PMID:16741141\|RGD:1599391
Cellular Component	GO:0016020	membrane	ATP7B	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Atp7b	IDA		Mouse	PMID:10441329
Cellular Component	GO:0016020	membrane	Atp7b	IDA		Mouse	PMID:15634671
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ATP7B	IDA		Human	PMID:16939419
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Atp7b	IDA		Rat	PMID:24614235\|RGD:11341682
Cellular Component	GO:0005886	plasma membrane	Atp7b	IDA		Rat	PMID:15994426\|RGD:1581816
Cellular Component	GO:0070160	tight junction	Atp7b	IDA		Rat	PMID:18395099\|RGD:2292671
Cellular Component	GO:0005802	trans-Golgi network	ATP7B	IDA		Human	PMID:15269005
Cellular Component	GO:0005802	trans-Golgi network	ATP7B	IDA		Human	PMID:16472602
Cellular Component	GO:0005802	trans-Golgi network	Atp7b	IDA		Mouse	PMID:11085952
Cellular Component	GO:0005802	trans-Golgi network	Atp7b	IDA		Rat	PMID:15994426\|RGD:1581816
Cellular Component	GO:0032588	trans-Golgi network membrane	ATP7B	IDA		Human	PMID:9837819
Biological Process	GO:0071280	cellular response to copper ion	Atp7b	IEP		Rat	PMID:24614235\|RGD:11341682
Biological Process	GO:0071280	cellular response to copper ion	Atp7b	IMP		Rat	PMID:24614235\|RGD:11341682
Biological Process	GO:0071287	cellular response to manganese ion	Atp7b	IEP		Rat	PMID:24614235\|RGD:11341682
Biological Process	GO:0007623	circadian rhythm	Atp7b	IEP		Rat	PMID:9920665\|RGD:1599396
Biological Process	GO:0060003	copper ion export	Atp7b	IMP		Rat	PMID:24614235\|RGD:11341682
Biological Process	GO:0015677	copper ion import	ATP7B	IDA		Human	PMID:16472602
Biological Process	GO:0006825	copper ion transport	ATP7B	IGI	UniProtKB:P38995	Human	PMID:12572677
Biological Process	GO:0006825	copper ion transport	ATP7B	IDA		Human	PMID:26004889
Biological Process	GO:0006825	copper ion transport	ATP7B	IGI	UniProtKB:P38995	Human	PMID:26004889
Biological Process	GO:0006825	copper ion transport	ATP7B	IMP		Human	PMID:9837819
Biological Process	GO:0006825	copper ion transport	Atp7b	IDA		Mouse	PMID:11237756
Biological Process	GO:0006825	copper ion transport	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:11085952
Biological Process	GO:0006825	copper ion transport	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:11237756
Biological Process	GO:0006825	copper ion transport	Atp7b	IDA		Mouse	PMID:15634671
Biological Process	GO:0051649	establishment of localization in cell	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:11085952
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:11085952
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:8040371
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:8257436
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:1588441
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:9392450
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:6863890
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7b	IMP	MGI:MGI:2158253	Mouse	PMID:10441329
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:2845190
Biological Process	GO:0006878	intracellular copper ion homeostasis	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:9484715
Biological Process	GO:0006882	intracellular zinc ion homeostasis	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:8040371
Biological Process	GO:0006882	intracellular zinc ion homeostasis	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:9392450
Biological Process	GO:0006882	intracellular zinc ion homeostasis	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:8257436
Biological Process	GO:0006882	intracellular zinc ion homeostasis	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:9484715
Biological Process	GO:0007595	lactation	Atp7b	IMP	MGI:MGI:1856221	Mouse	MGI:MGI:71982
Biological Process	GO:0007595	lactation	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:6863890
Biological Process	GO:0007595	lactation	Atp7b	IMP	MGI:MGI:1856220	Mouse	PMID:1588441
Biological Process	GO:0007595	lactation	Atp7b	IEP		Rat	PMID:16741141\|RGD:1599391
Biological Process	GO:0007595	lactation	Atp7b	IEP		Rat	PMID:28089327\|RGD:25671605
Biological Process	GO:0015680	protein maturation by copper ion transfer	Atp7b	IMP	MGI:MGI:2158253	Mouse	PMID:16436657
Biological Process	GO:0051591	response to cAMP	Atp7b	IEP		Rat	PMID:9920665\|RGD:1599396
Biological Process	GO:0046688	response to copper ion	ATP7B	IDA		Human	PMID:15269005
Biological Process	GO:0046688	response to copper ion	ATP7B	IDA		Human	PMID:16472602
Biological Process	GO:0046688	response to copper ion	ATP7B	IDA		Human	PMID:16939419
Biological Process	GO:0046688	response to copper ion	Atp7b	IEP		Rat	PMID:15591161\|RGD:1599393
Biological Process	GO:1990637	response to prolactin	Atp7b	IEP		Rat	PMID:16741141\|RGD:1599391
Biological Process	GO:0010043	response to zinc ion	Atp7b	IEP		Rat	PMID:12840169\|RGD:1599394
Biological Process	GO:0051208	sequestering of calcium ion	ATP7B	IDA		Human	PMID:16472602

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.