Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATP8A1
  • Mouse genes Atp8a1
  • Rat genes Atp8a1
  • Zfish genes atp8a1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp8a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140346	phosphatidylserine flippase activity	ATP8A1	IDA		Human	PMID:31416931
Molecular Function	GO:0140346	phosphatidylserine flippase activity	Atp8a1	IMP		Mouse	MGI:MGI:6378348|PMID:20224745
Molecular Function	GO:0005515	protein binding	ATP8A1	IPI	UniProtKB:Q9NV96	Human	PMID:20947505
Molecular Function	GO:0005515	protein binding	ATP8A1	IPI	UniProtKB:Q9NV96	Human	PMID:20961850
Molecular Function	GO:0005515	protein binding	ATP8A1	IPI	UniProtKB:Q9NV96	Human	PMID:21914794
Molecular Function	GO:0005515	protein binding	Atp8a1	IPI	UniProtKB:Q8VEK0	Mouse	MGI:MGI:6294211|PMID:30086173
Molecular Function	GO:0005515	protein binding	Atp8a1	IPI	PR:Q8VEK0	Mouse	PMID:23269685
Cellular Component	GO:0031410	cytoplasmic vesicle	Atp8a1	IDA		Mouse	MGI:MGI:6105409|PMID:27287255
Cellular Component	GO:0031410	cytoplasmic vesicle	Atp8a1	IDA		Mouse	MGI:MGI:6378348|PMID:20224745
Cellular Component	GO:0005829	cytosol	ATP8A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	ATP8A1	IDA		Human	PMID:21914794
Cellular Component	GO:0070062	extracellular exosome	ATP8A1	HDA		Human	PMID:23533145
Cellular Component	GO:0005794	Golgi apparatus	ATP8A1	IDA		Human	PMID:20947505
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ATP8A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	ATP8A1	HDA		Human	PMID:19946888
Cellular Component	GO:0031090	organelle membrane	Atp8a1	IDA		Mouse	MGI:MGI:6459414|PMID:30674456
Cellular Component	GO:1990531	phospholipid-translocating ATPase complex	ATP8A1	IPI		Human	PMID:20961850
Cellular Component	GO:1990531	phospholipid-translocating ATPase complex	ATP8A1	IPI		Human	PMID:31416931
Cellular Component	GO:1990531	phospholipid-translocating ATPase complex	ATP8A1	IDA		Human	PMID:31416931
Cellular Component	GO:0005886	plasma membrane	ATP8A1	IDA		Human	PMID:20947505
Cellular Component	GO:0045202	synapse	Atp8a1	IDA		Mouse	PMID:27287255
Cellular Component	GO:0030672	synaptic vesicle membrane	Atp8a1	EXP		Rat	PMID:23622064|RGD:13702180
Cellular Component	GO:0030672	synaptic vesicle membrane	Atp8a1	IDA		Rat	PMID:23622064|RGD:13702180
Biological Process	GO:0140331	aminophospholipid translocation	ATP8A1	IDA		Human	PMID:31416931
Biological Process	GO:0140331	aminophospholipid translocation	Atp8a1	IMP		Mouse	MGI:MGI:6378348|PMID:20224745
Biological Process	GO:0007612	learning	Atp8a1	IMP		Mouse	MGI:MGI:5302172|PMID:22007859
Biological Process	GO:0030335	positive regulation of cell migration	Atp8a1	IMP		Mouse	MGI:MGI:5490839|PMID:23269685
Biological Process	GO:0061092	positive regulation of phospholipid translocation	Atp8a1	IDA		Mouse	MGI:MGI:5302172|PMID:22007859

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern