Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATP8A2
  • Mouse genes Atp8a2
  • Rat genes Atp8a2
  • Zfish genes atp8a2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp8a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015247	aminophospholipid flippase activity	Atp8a2	IMP		Mouse	MGI:MGI:5439211|PMID:22912588
Molecular Function	GO:0005515	protein binding	ATP8A2	IPI	UniProtKB:Q9NV96	Human	PMID:31397519
Cellular Component	GO:0005768	endosome	Atp8a2	IDA		Mouse	MGI:MGI:5574432|PMID:24413176
Cellular Component	GO:0005794	Golgi apparatus	ATP8A2	IDA		Human	PMID:20947505
Cellular Component	GO:0005794	Golgi apparatus	Atp8a2	IDA		Mouse	MGI:MGI:5574432|PMID:24413176
Cellular Component	GO:0016020	membrane	Atp8a2	IDA		Mouse	MGI:MGI:5439211|PMID:22912588
Cellular Component	GO:0005654	nucleoplasm	ATP8A2	IDA		Human	GO_REF:0000052
Cellular Component	GO:1990531	phospholipid-translocating ATPase complex	ATP8A2	IPI		Human	PMID:20947505
Cellular Component	GO:0005886	plasma membrane	ATP8A2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ATP8A2	IDA		Human	PMID:20947505
Biological Process	GO:0007409	axonogenesis	Atp8a2	IMP	MGI:MGI:1856273	Mouse	PMID:1634998
Biological Process	GO:0050908	detection of light stimulus involved in visual perception	Atp8a2	IMP		Mouse	MGI:MGI:5574432|PMID:24413176
Biological Process	GO:0008340	determination of adult lifespan	Atp8a2	IMP	MGI:MGI:1856273	Mouse	PMID:1634998
Biological Process	GO:0042755	eating behavior	Atp8a2	IMP	MGI:MGI:1856273	Mouse	PMID:1634998
Biological Process	GO:0042472	inner ear morphogenesis	Atp8a2	IMP		Mouse	MGI:MGI:5574432|PMID:24413176
Biological Process	GO:0003011	involuntary skeletal muscle contraction	Atp8a2	IMP	MGI:MGI:1856273	Mouse	PMID:1634998
Biological Process	GO:0060052	neurofilament cytoskeleton organization	Atp8a2	IMP		Mouse	MGI:MGI:5439211|PMID:22912588
Biological Process	GO:0050884	neuromuscular process controlling posture	Atp8a2	IMP	MGI:MGI:1856273	Mouse	PMID:1634998
Biological Process	GO:0048666	neuron development	Atp8a2	IMP	MGI:MGI:1856273	Mouse	PMID:1634998
Biological Process	GO:0031175	neuron projection development	Atp8a2	IMP		Rat	PMID:22641037|RGD:8553641
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Atp8a2	IMP	MGI:MGI:1856273	Mouse	PMID:1634998
Biological Process	GO:0010976	positive regulation of neuron projection development	Atp8a2	IDA		Mouse	MGI:MGI:5429112|PMID:22641037
Biological Process	GO:0061092	positive regulation of phospholipid translocation	Atp8a2	IDA		Mouse	MGI:MGI:5439211|PMID:22912588
Biological Process	GO:0010996	response to auditory stimulus	Atp8a2	IMP		Mouse	MGI:MGI:5574432|PMID:24413176
Biological Process	GO:0010842	retina layer formation	Atp8a2	IMP		Mouse	MGI:MGI:5574432|PMID:24413176
Biological Process	GO:0043588	skin development	Atp8a2	IMP	MGI:MGI:1856273	Mouse	PMID:1634998

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern