Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATXN7
  • Mouse genes Atxn7
  • Rat genes Atxn7
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atxn7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Atxn7	IDA		Mouse	PMID:14613968
Molecular Function	GO:0005515	protein binding	ATXN7	IPI	UniProtKB:Q9BX66	Human	PMID:11371513
Molecular Function	GO:0005515	protein binding	ATXN7	IPI	UniProtKB:Q12962	Human	PMID:15115762
Molecular Function	GO:0005515	protein binding	ATXN7	IPI	UniProtKB:Q9Y4A5	Human	PMID:15115762
Molecular Function	GO:0005515	protein binding	ATXN7	IPI	UniProtKB:P02283	Human	PMID:20634802
Molecular Function	GO:0005515	protein binding	ATXN7	IPI	UniProtKB:O00339	Human	PMID:21078624
Molecular Function	GO:0005515	protein binding	ATXN7	IPI	UniProtKB:O00468	Human	PMID:21078624
Molecular Function	GO:0005515	protein binding	ATXN7	IPI	UniProtKB:O75095	Human	PMID:21078624
Molecular Function	GO:0005515	protein binding	ATXN7	IPI	UniProtKB:P37198	Human	PMID:21078624
Molecular Function	GO:0005515	protein binding	ATXN7	IPI	UniProtKB:Q7Z7M0	Human	PMID:21078624
Molecular Function	GO:0005515	protein binding	ATXN7	IPI	UniProtKB:Q8IUQ4	Human	PMID:21078624
Molecular Function	GO:0005515	protein binding	ATXN7	IPI	UniProtKB:Q8N2S1	Human	PMID:21078624
Molecular Function	GO:0005515	protein binding	ATXN7	IPI	UniProtKB:Q9P209	Human	PMID:21078624
Molecular Function	GO:0005515	protein binding	ATXN7	IPI	UniProtKB:Q9Y3T9	Human	PMID:21078624
Molecular Function	GO:0005515	protein binding	ATXN7	IPI	UniProtKB:Q9BX66	Human	PMID:23892081
Molecular Function	GO:0005515	protein binding	ATXN7	IPI	UniProtKB:Q12962	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	ATXN7	IPI	UniProtKB:Q9Y4A5	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	Atxn7	IPI	UniProtKB:Q80YV3	Mouse	MGI:MGI:3620296|PMID:16494529
Molecular Function	GO:0005515	protein binding	Atxn7	IPI	UniProtKB:Q80YV3	Mouse	MGI:MGI:4462751|PMID:20508642
Molecular Function	GO:0005515	protein binding	Atxn7	IPI	PR:O54751	Mouse	PMID:14613968
Cellular Component	GO:0005737	cytoplasm	Atxn7	IDA		Mouse	PMID:12039035
Cellular Component	GO:0005829	cytosol	ATXN7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0015630	microtubule cytoskeleton	ATXN7	IDA		Human	PMID:22100762
Cellular Component	GO:0005654	nucleoplasm	ATXN7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ATXN7	IDA		Human	PMID:22100762
Cellular Component	GO:0005634	nucleus	Atxn7	IDA		Mouse	PMID:12039035
Cellular Component	GO:0005634	nucleus	Atxn7	IDA		Mouse	PMID:14613968
Biological Process	GO:0043966	histone H3 acetylation	ATXN7	IDA		Human	PMID:10373431
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	Atxn7	IMP	MGI:MGI:2651378	Mouse	PMID:18216249
Biological Process	GO:0000226	microtubule cytoskeleton organization	ATXN7	IMP		Human	PMID:22100762
Biological Process	GO:0035521	monoubiquitinated histone deubiquitination	ATXN7	IDA		Human	PMID:18206972
Biological Process	GO:0035522	monoubiquitinated histone H2A deubiquitination	ATXN7	IDA		Human	PMID:18206972
Biological Process	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	Atxn7	IMP	MGI:MGI:2651378	Mouse	PMID:18216249
Biological Process	GO:0007026	negative regulation of microtubule depolymerization	ATXN7	IMP		Human	PMID:22100762
Biological Process	GO:0042326	negative regulation of phosphorylation	Atxn7	IMP	MGI:MGI:2651378	Mouse	PMID:18216249
Biological Process	GO:0016310	phosphorylation	Atxn7	IMP	MGI:MGI:2651378	Mouse	PMID:18216249
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Atxn7	IMP	MGI:MGI:2651378	Mouse	PMID:18216249
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ATXN7	IDA		Human	PMID:9603525
Biological Process	GO:0006366	transcription by RNA polymerase II	Atxn7	IMP	MGI:MGI:2651378	Mouse	PMID:18216249

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern