Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AVIL
  • Mouse genes Avil
  • Rat genes Avil
  • Zfish genes avil
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Avil

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Avil	IDA		Rat	PMID:11849295|RGD:634623
Molecular Function	GO:0051015	actin filament binding	AVIL	IDA		Human	PMID:29058690
Molecular Function	GO:0071933	Arp2/3 complex binding	AVIL	IDA		Human	PMID:29058690
Molecular Function	GO:0005515	protein binding	AVIL	IPI	UniProtKB:P61158,UniProtKB:P61160|UniProtKB:Q9P212	Human	PMID:29058690
Molecular Function	GO:0005515	protein binding	Avil	IPI	PR:Q5ND28	Mouse	PMID:15247299
Cellular Component	GO:0005884	actin filament	AVIL	IDA		Human	PMID:29058690
Cellular Component	GO:0042995	cell projection	Avil	IDA		Rat	PMID:11849295|RGD:634623
Cellular Component	GO:0005925	focal adhesion	AVIL	IDA		Human	PMID:29058690
Cellular Component	GO:0030027	lamellipodium	AVIL	IDA		Human	PMID:29058690
Cellular Component	GO:0043005	neuron projection	Avil	IDA		Rat	PMID:11849295|RGD:634623
Biological Process	GO:0007015	actin filament organization	AVIL	IMP		Human	PMID:29058690
Biological Process	GO:0060271	cilium assembly	AVIL	IMP		Human	PMID:20393563
Biological Process	GO:0007399	nervous system development	Avil	IDA		Rat	PMID:11849295|RGD:634623
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	AVIL	IMP		Human	PMID:29058690
Biological Process	GO:0010976	positive regulation of neuron projection development	Avil	IDA		Mouse	MGI:MGI:3056881|PMID:15247299
Biological Process	GO:0010976	positive regulation of neuron projection development	Avil	IDA		Rat	PMID:11849295|RGD:634623
Biological Process	GO:1900480	regulation of diacylglycerol biosynthetic process	AVIL	IMP		Human	PMID:29058690

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern