Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AVP
  • Mouse genes Avp
  • Rat genes Avp
  • Zfish genes avp,oxt
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Avp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	AVP	IDA		Human	PMID:18402937
Molecular Function	GO:0005184	neuropeptide hormone activity	AVP	IDA		Human	PMID:18402937
Molecular Function	GO:0005184	neuropeptide hormone activity	Avp	IDA		Rat	PMID:19560475|RGD:2312653
Molecular Function	GO:0005515	protein binding	AVP	IPI	UniProtKB:O43741	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AVP	IPI	UniProtKB:P0DTC2,UniProtKB:Q9BYF1	Human	PMID:33713620
Molecular Function	GO:0005515	protein binding	Avp	IPI	RGD:3671	Rat	PMID:15927785|RGD:1625246
Molecular Function	GO:0004672	protein kinase activity	AVP	IDA		Human	PMID:18402937
Molecular Function	GO:0031894	V1A vasopressin receptor binding	AVP	IPI	UniProtKB:P37288	Human	PMID:18402937
Molecular Function	GO:0031894	V1A vasopressin receptor binding	Avp	IMP		Rat	PMID:12942143|RGD:1358326
Molecular Function	GO:0031894	V1A vasopressin receptor binding	Avp	IDA		Rat	PMID:19560475|RGD:2312653
Molecular Function	GO:0031895	V1B vasopressin receptor binding	Avp	IMP		Rat	PMID:7624319|RGD:61542
Cellular Component	GO:0043203	axon hillock	avp	IDA		Zfish	PMID:18330923
Cellular Component	GO:0030425	dendrite	Avp	IDA		Rat	PMID:12829321|RGD:2312643
Cellular Component	GO:0030425	dendrite	Avp	IDA		Rat	PMID:18483147|RGD:2301932
Cellular Component	GO:0005576	extracellular region	AVP	IDA		Human	PMID:33713620
Cellular Component	GO:0005615	extracellular space	Avp	IDA		Rat	PMID:18596120|RGD:2301931
Cellular Component	GO:0043025	neuronal cell body	avp	IDA		Zfish	PMID:18330923
Cellular Component	GO:0098992	neuronal dense core vesicle	Avp	IDA		Rat	PMID:30519837|RGD:155230768
Cellular Component	GO:0030141	secretory granule	Avp	IDA		Rat	PMID:18483147|RGD:2301932
Biological Process	GO:0070371	ERK1 and ERK2 cascade	AVP	IDA		Human	PMID:18402937
Biological Process	GO:0007625	grooming behavior	Avp	IMP		Rat	PMID:18640147|RGD:2300335
Biological Process	GO:0042538	hyperosmotic salinity response	Avp	IEP		Rat	PMID:18088359|RGD:2304116
Biological Process	GO:0007626	locomotory behavior	Avp	IMP		Rat	PMID:18786571|RGD:2301929
Biological Process	GO:0002125	maternal aggressive behavior	Avp	IMP		Rat	PMID:18640147|RGD:2300335
Biological Process	GO:0042711	maternal behavior	Avp	IMP		Rat	PMID:18955705|RGD:2301926
Biological Process	GO:0050801	monoatomic ion homeostasis	oxt	IMP	ZFIN:ZDB-MRPHLNO-110802-5	Zfish	PMID:21104292
Biological Process	GO:0050891	multicellular organismal-level water homeostasis	Avp	IMP		Rat	PMID:15231996|RGD:1304346
Biological Process	GO:0043066	negative regulation of apoptotic process	AVP	IDA		Human	PMID:18402937
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	AVP	IDA		Human	PMID:18402937
Biological Process	GO:0007621	negative regulation of female receptivity	Avp	IMP		Rat	PMID:16488546|RGD:1579755
Biological Process	GO:0090201	negative regulation of release of cytochrome c from mitochondria	AVP	IDA		Human	PMID:18402937
Biological Process	GO:0051970	negative regulation of transmission of nerve impulse	Avp	IMP		Rat	PMID:16304841|RGD:2300377
Biological Process	GO:0043084	penile erection	Avp	IMP		Rat	PMID:2300336|RGD:2301935
Biological Process	GO:0030307	positive regulation of cell growth	Avp	IMP		Rat	PMID:17395547|RGD:2300346
Biological Process	GO:0008284	positive regulation of cell population proliferation	Avp	IMP		Rat	PMID:18787031|RGD:2301928
Biological Process	GO:0032849	positive regulation of cellular pH reduction	Avp	IMP		Rat	PMID:17762181|RGD:2300343
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Avp	IMP		Rat	PMID:17877638|RGD:2300342
Biological Process	GO:0010628	positive regulation of gene expression	AVP	IDA		Human	PMID:18538351
Biological Process	GO:0014049	positive regulation of glutamate secretion	Avp	IMP		Rat	PMID:17877638|RGD:2300342
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	AVP	IDA		Human	PMID:18402937
Biological Process	GO:0031394	positive regulation of prostaglandin biosynthetic process	Avp	IMP		Rat	PMID:17254553|RGD:2300349
Biological Process	GO:0003084	positive regulation of systemic arterial blood pressure	Avp	IDA		Rat	PMID:18957383|RGD:2301925
Biological Process	GO:0045907	positive regulation of vasoconstriction	Avp	IMP		Rat	PMID:18483147|RGD:2301932
Biological Process	GO:0070528	protein kinase C signaling	AVP	IDA		Human	PMID:18402937
Biological Process	GO:0035813	regulation of renal sodium excretion	Avp	IMP		Rat	PMID:18596120|RGD:2301931
Biological Process	GO:0045471	response to ethanol	Avp	IEP		Rat	PMID:18464746|RGD:2301940
Biological Process	GO:0035094	response to nicotine	Avp	IEP		Rat	PMID:18337407|RGD:2301941
Biological Process	GO:0014070	response to organic cyclic compound	Avp	IEP		Rat	PMID:18824019|RGD:2301927
Biological Process	GO:0033574	response to testosterone	Avp	IEP		Rat	PMID:18685071|RGD:2301930
Biological Process	GO:0007165	signal transduction	AVP	IDA		Human	PMID:18402937
Biological Process	GO:0035176	social behavior	Avp	IMP		Rat	PMID:18786571|RGD:2301929
Biological Process	GO:0036269	swimming behavior	oxt	IMP	ZFIN:ZDB-GENO-220125-1	Zfish	PMID:31358991
Biological Process	GO:0046718	viral entry into host cell	AVP	IDA		Human	PMID:33713620

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern