Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AVPR2
  • Mouse genes Avpr2
  • Rat genes Avpr2
  • Zfish genes avpr2aa,avpr2ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Avpr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	AVPR2	IPI	UniProtKB:Q9BXJ1	Human	PMID:12409230
Molecular Function	GO:0005515	protein binding	AVPR2	IPI	UniProtKB:Q9BVK8	Human	PMID:21056967
Molecular Function	GO:0005515	protein binding	AVPR2	IPI	UniProtKB:Q8NCT1	Human	PMID:23236378
Molecular Function	GO:0005515	protein binding	AVPR2	IPI	UniProtKB:P21964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AVPR2	IPI	UniProtKB:Q8IVJ1	Human	PMID:32296183
Molecular Function	GO:0005000	vasopressin receptor activity	AVPR2	IDA		Human	PMID:9322919
Cellular Component	GO:0030139	endocytic vesicle	AVPR2	IDA		Human	PMID:14757828
Cellular Component	GO:0005768	endosome	AVPR2	IDA		Human	PMID:14757828
Cellular Component	GO:0048471	perinuclear region of cytoplasm	AVPR2	IDA		Human	PMID:14757828
Cellular Component	GO:0005886	plasma membrane	AVPR2	IDA		Human	PMID:14757828
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Avpr2	IMP	MGI:MGI:2384212	Mouse	PMID:10395695
Biological Process	GO:0008285	negative regulation of cell population proliferation	AVPR2	IDA		Human	PMID:9322919
Biological Process	GO:0035814	negative regulation of renal sodium excretion	Avpr2	IMP		Rat	PMID:18596120|RGD:2301931
Biological Process	GO:0035811	negative regulation of urine volume	Avpr2	IMP		Rat	PMID:18057218|RGD:2304118
Biological Process	GO:0045777	positive regulation of blood pressure	Avpr2	IDA		Rat	PMID:12072411|RGD:1298694
Biological Process	GO:0008284	positive regulation of cell population proliferation	Avpr2	IMP		Rat	PMID:18787031|RGD:2301928
Biological Process	GO:0010628	positive regulation of gene expression	Avpr2	IMP		Rat	PMID:16352747|RGD:8553330
Biological Process	GO:0003084	positive regulation of systemic arterial blood pressure	Avpr2	IMP		Rat	PMID:18957383|RGD:2301925
Biological Process	GO:0034097	response to cytokine	Avpr2	IMP	MGI:MGI:2384212	Mouse	PMID:10395695
Biological Process	GO:0021537	telencephalon development	Avpr2	IEP		Rat	PMID:11021977|RGD:2304223
Biological Process	GO:0032609	type II interferon production	Avpr2	IMP	MGI:MGI:2384212	Mouse	PMID:10395695

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern