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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse B2m

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set B2m
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0042802identical protein bindingB2MIPIUniProtKB:P61769HumanPMID:17108084
Molecular FunctionGO:0042802identical protein bindingB2MIPIUniProtKB:P61769HumanPMID:18579777
Molecular FunctionGO:0042802identical protein bindingB2MIPIUniProtKB:P61769HumanPMID:19172750
Molecular FunctionGO:0042802identical protein bindingB2MIPIUniProtKB:P61769HumanPMID:19564620
Molecular FunctionGO:0042802identical protein bindingB2MIPIUniProtKB:P61769HumanPMID:20826442
Molecular FunctionGO:0042802identical protein bindingB2MIPIUniProtKB:P61769HumanPMID:21131979
Molecular FunctionGO:0042802identical protein bindingB2MIPIUniProtKB:P61769HumanPMID:21220305
Molecular FunctionGO:0042802identical protein bindingB2MIPIUniProtKB:P61769HumanPMID:21569201
Molecular FunctionGO:0042802identical protein bindingB2MIPIUniProtKB:P61769HumanPMID:22289140
Molecular FunctionGO:0042802identical protein bindingB2MIPIUniProtKB:P61769HumanPMID:22575645
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:P29016HumanPMID:12118248
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:P06126HumanPMID:12833155
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:P29016HumanPMID:14764708
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:P06126HumanPMID:15723809
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:Q30201HumanPMID:15965644
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:Q03518HumanPMID:18802093
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:Q9BZW8HumanPMID:20164429
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:Q30201HumanPMID:20618438
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:Q95460-1HumanPMID:23051753
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:P12004HumanPMID:23527218
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:P12004HumanPMID:26030842
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:Q95460HumanPMID:27043408
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:P29016HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:Q9Y3Y4HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:P13747HumanPMID:9427624
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:Q30201HumanPMID:9465039
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:Q30201HumanPMID:9546397
Molecular FunctionGO:0005515protein bindingB2MIPIUniProtKB:Q30201HumanPMID:9990067
Molecular FunctionGO:0005515protein bindingB2mIPIPR:Q8HWE7MousePMID:16920948
Molecular FunctionGO:0005515protein bindingB2mIPIPR:P14427MousePMID:14735325
Molecular FunctionGO:0005515protein bindingB2mIPIPR:Q8HWE5MousePMID:16920948
Molecular FunctionGO:0042803protein homodimerization activityB2MIDAHumanPMID:28468825
Cellular ComponentGO:0005829cytosolB2MIDAHumanGO_REF:0000052
Cellular ComponentGO:0009897external side of plasma membraneB2mIDAMousePMID:1538753
Cellular ComponentGO:0070062extracellular exosomeB2MHDAHumanPMID:19056867
Cellular ComponentGO:0070062extracellular exosomeB2MHDAHumanPMID:19199708
Cellular ComponentGO:0070062extracellular exosomeB2MHDAHumanPMID:23533145
Cellular ComponentGO:0005615extracellular spaceB2MHDAHumanPMID:16502470
Cellular ComponentGO:0005615extracellular spaceB2MHDAHumanPMID:22664934
Cellular ComponentGO:0005615extracellular spaceB2mHDAMouseMGI:MGI:5640941|PMID:24006456
Cellular ComponentGO:0005615extracellular spaceB2mIDARatPMID:3516141|RGD:1599431
Cellular ComponentGO:0005925focal adhesionB2MHDAHumanPMID:21423176
Cellular ComponentGO:0005794Golgi apparatusB2MIDAHumanGO_REF:0000052
Cellular ComponentGO:1990712HFE-transferrin receptor complexB2MIDAHumanPMID:9990067
Cellular ComponentGO:0016020membraneB2MHDAHumanPMID:19946888
Cellular ComponentGO:0042824MHC class I peptide loading complexB2MIDAHumanPMID:21263072
Cellular ComponentGO:0005886plasma membraneB2MIDAHumanGO_REF:0000052
Biological ProcessGO:1990000amyloid fibril formationB2MIDAHumanPMID:28468825
Biological ProcessGO:0019885antigen processing and presentation of endogenous peptide antigen via MHC class IB2MIGIUniProtKB:P04439HumanPMID:24643698
Biological ProcessGO:0002481antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependentB2mIMPMousePMID:16299293
Biological ProcessGO:0071281cellular response to iron ionB2MIGIUniProtKB:P02787,UniProtKB:Q07891,UniProtKB:Q30201,UniProtKB:Q9UP52HumanPMID:18353247
Biological ProcessGO:0071283cellular response to iron(III) ionB2mIMPMGI:MGI:1927183MousePMID:9531620
Biological ProcessGO:0071316cellular response to nicotineB2MIMPHumanPMID:28213472
Biological ProcessGO:0006879intracellular iron ion homeostasisB2MIDAHumanPMID:18353247
Biological ProcessGO:0006826iron ion transportB2mIMPMGI:MGI:1927183MousePMID:9531620
Biological ProcessGO:0007611learning or memoryB2MIDAHumanPMID:26147761
Biological ProcessGO:0007611learning or memoryB2mIMPMouseMGI:MGI:6095052|PMID:28864206
Biological ProcessGO:0007611learning or memoryB2mIMPMouseMGI:MGI:5708430|PMID:26147761
Biological ProcessGO:0060586multicellular organismal-level iron ion homeostasisB2mIMPMousePMID:11113132
Biological ProcessGO:0050680negative regulation of epithelial cell proliferationB2MIDAHumanPMID:28213472
Biological ProcessGO:2000978negative regulation of forebrain neuron differentiationB2MIDAHumanPMID:26147761
Biological ProcessGO:2000978negative regulation of forebrain neuron differentiationB2mIMPMouseMGI:MGI:5708430|PMID:26147761
Biological ProcessGO:0050768negative regulation of neurogenesisB2MIDAHumanPMID:26147761
Biological ProcessGO:0050768negative regulation of neurogenesisB2mIMPMouseMGI:MGI:5708430|PMID:26147761
Biological ProcessGO:0010977negative regulation of neuron projection developmentB2mIGIMGI:MGI:95896MousePMID:20018625
Biological ProcessGO:1900121negative regulation of receptor bindingB2MIDAHumanPMID:9465039
Biological ProcessGO:2000774positive regulation of cellular senescenceB2MIDAHumanPMID:28213472
Biological ProcessGO:1904434positive regulation of ferrous iron bindingB2MIGIUniProtKB:P02786|UniProtKB:P02787|UniProtKB:Q30201|UniProtKB:Q9UP52HumanPMID:18353247
Biological ProcessGO:0032092positive regulation of protein bindingB2MIGIUniProtKB:P02787,UniProtKB:Q07891,UniProtKB:Q30201,UniProtKB:Q9UP52HumanPMID:18353247
Biological ProcessGO:1900122positive regulation of receptor bindingB2MIGIUniProtKB:P02787,UniProtKB:Q07891,UniProtKB:Q30201,UniProtKB:Q9UP52HumanPMID:18353247
Biological ProcessGO:0048260positive regulation of receptor-mediated endocytosisB2MIGIUniProtKB:P02787,UniProtKB:Q07891,UniProtKB:Q30201,UniProtKB:Q9UP52HumanPMID:18353247
Biological ProcessGO:0002726positive regulation of T cell cytokine productionB2MIDAHumanPMID:24643698
Biological ProcessGO:0001916positive regulation of T cell mediated cytotoxicityB2mIMPMousePMID:16299293
Biological ProcessGO:1904437positive regulation of transferrin receptor bindingB2MIGIUniProtKB:P02786|UniProtKB:P02787|UniProtKB:Q30201|UniProtKB:Q9UP52HumanPMID:18353247
Biological ProcessGO:0051289protein homotetramerizationB2MIMPHumanPMID:28468825
Biological ProcessGO:0042026protein refoldingB2mIDAMousePMID:16920948
Biological ProcessGO:0045646regulation of erythrocyte differentiationB2mIMPMGI:MGI:1927183MousePMID:9531620
Biological ProcessGO:0034756regulation of iron ion transportB2MIGIUniProtKB:P02786|UniProtKB:P02787|UniProtKB:Q30201|UniProtKB:Q9UP52HumanPMID:18353247
Biological ProcessGO:0046686response to cadmium ionB2mIEPRatPMID:17327699|RGD:2293801
Biological ProcessGO:0002237response to molecule of bacterial originB2mIMPMousePMID:16299293
Biological ProcessGO:0009410response to xenobiotic stimulusB2mIEPRatPMID:17211973|RGD:1599430
Biological ProcessGO:0001895retina homeostasisB2MHEPHumanPMID:23580065
Biological ProcessGO:0007608sensory perception of smellB2mIMPMouseMGI:MGI:1860385|PMID:10912502
Biological ProcessGO:0033077T cell differentiation in thymusB2mIGIMGI:MGI:95663MousePMID:18776904
Biological ProcessGO:0001913T cell mediated cytotoxicityB2mIMPMousePMID:16299293

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory