Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BACH1
  • Mouse genes Bach1
  • Rat genes Bach1
  • Zfish genes bach1a,bach1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bach1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Bach1	IDA		Mouse	PMID:8887638
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Bach1	IDA		Mouse	MGI:MGI:894637|PMID:8887638
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Bach1	IDA		Mouse	MGI:MGI:3838696|PMID:19170764
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Bach1	IDA		Mouse	PMID:8887638
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	BACH1	IDA		Human	PMID:12511571
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	BACH1	IMP		Human	PMID:21555518
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	BACH1	IDA		Human	PMID:24035498
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Bach1	IDA		Mouse	MGI:MGI:894637|PMID:8887638
Molecular Function	GO:0005515	protein binding	BACH1	IPI	UniProtKB:O15525	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	BACH1	IPI	UniProtKB:O75444	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	BACH1	IPI	UniProtKB:P15336	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	BACH1	IPI	UniProtKB:P35638	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	BACH1	IPI	UniProtKB:Q9DGW5	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	BACH1	IPI	UniProtKB:Q9Y5Q3	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	BACH1	IPI	UniProtKB:O15525	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	BACH1	IPI	UniProtKB:P15336	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	BACH1	IPI	UniProtKB:P35638	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	BACH1	IPI	UniProtKB:Q9ULX9	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	BACH1	IPI	UniProtKB:Q9Y5Q3	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	BACH1	IPI	UniProtKB:O15525	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	BACH1	IPI	UniProtKB:Q9ULX9	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	BACH1	IPI	UniProtKB:O15525	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BACH1	IPI	UniProtKB:Q9ULX9	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BACH1	IPI	UniProtKB:O60260-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BACH1	IPI	UniProtKB:P40337-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Bach1	IPI	UniProtKB:P02340|UniProtKB:Q61827	Mouse	MGI:MGI:5927053|PMID:19011633
Molecular Function	GO:0005515	protein binding	Bach1	IPI	PR:Q61827	Mouse	PMID:8887638
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Bach1	IDA		Mouse	MGI:MGI:894637|PMID:8887638
Molecular Function	GO:0000976	transcription cis-regulatory region binding	bach1b	IDA		Zfish	PMID:24652768
Cellular Component	GO:0005737	cytoplasm	BACH1	HDA		Human	PMID:16791210
Cellular Component	GO:0005829	cytosol	BACH1	HDA		Human	PMID:16780588
Cellular Component	GO:0005634	nucleus	BACH1	HDA		Human	PMID:16780588
Cellular Component	GO:0005634	nucleus	BACH1	IDA		Human	PMID:12511571
Cellular Component	GO:0005634	nucleus	BACH1	HDA		Human	PMID:16791210
Cellular Component	GO:0005634	nucleus	BACH1	IDA		Human	PMID:24035498
Cellular Component	GO:0005634	nucleus	Bach1	IDA		Mouse	PMID:8887638
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	BACH1	IPI		Human	PMID:20102225
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	BACH1	IPI		Human	PMID:23661758
Biological Process	GO:0006281	DNA repair	BACH1	IMP		Human	PMID:11301010
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	BACH1	IDA		Human	PMID:12511571
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	BACH1	IMP		Human	PMID:21555518
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	BACH1	IDA		Human	PMID:24035498
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Bach1	IDA		Mouse	MGI:MGI:894637|PMID:8887638
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bach1	IDA		Mouse	MGI:MGI:894637|PMID:8887638
Biological Process	GO:0006355	regulation of DNA-templated transcription	Bach1	IDA		Mouse	MGI:MGI:3838696|PMID:19170764
Biological Process	GO:0006355	regulation of DNA-templated transcription	Bach1	IDA		Mouse	PMID:8887638
Biological Process	GO:0006355	regulation of DNA-templated transcription	bach1b	IDA		Zfish	PMID:24652768
Biological Process	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	BACH1	IMP		Human	PMID:21555518
Biological Process	GO:0000117	regulation of transcription involved in G2/M transition of mitotic cell cycle	BACH1	IMP		Human	PMID:21555518

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern