Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BAG3
  • Mouse genes Bag3
  • Rat genes Bag3
  • Zfish genes bag3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bag3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000774	adenyl-nucleotide exchange factor activity	BAG3	IDA		Human	PMID:20060297
Molecular Function	GO:0000774	adenyl-nucleotide exchange factor activity	BAG3	IDA		Human	PMID:24318877
Molecular Function	GO:0045296	cadherin binding	BAG3	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q15038	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9UJY1	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q13501	Human	PMID:19229298
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9BSI4	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9UJY1	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:O75190	Human	PMID:22366786
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q8TEU7	Human	PMID:23434281
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9UMS6	Human	PMID:23434281
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:P0DMV8	Human	PMID:24318877
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:P0DMV9	Human	PMID:24318877
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:P11142	Human	PMID:24318877
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q5S007	Human	PMID:24510904
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:P04792	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q15773	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q969T9	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q96BE0	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9NR12	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9UJY1	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9UNE7	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:P04792	Human	PMID:25277244
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:O76083	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q15038	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q15427	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q96B67	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q96IS6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q99732	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9Y5V3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q00613	Human	PMID:26159920
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:P04792	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q15773	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9UJY1	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9UNE7	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:O00167-2	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9UJY1	Human	PMID:28144995
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9NR12	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9UJY1	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q99732	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:A0A087WSW0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:A1KXE4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:A8MTQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:O00167-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:O15496	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:O76083-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:P14373	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:P31321	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:P50570	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q01196-8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q05215	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q05BL1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q13133-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q15038	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q15427	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q15654	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q16082	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q16630-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q16825	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q6DHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q6ZSJ9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q7Z783	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q86TH3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q86UU5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q86V38	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q86WV8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q86XR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q8IUQ4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q8N9I9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q8NEA6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q8WUU8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q8WWB5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q969T9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q96B67	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q96DV4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q96PV6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q96RU7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q99732	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q99750	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9GZU7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9H1C7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9H2G9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9H9H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9H9P5-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9NPF4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9NQX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9NR12	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9NU39	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9NV39	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9UBY9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9UF11-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9UHR4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9UJY1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9Y5V3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9UJY1	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:O75446	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:P02489	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:P04792	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:P07196	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:P48643	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q09028	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q14204	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q86V38	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q8WZ19	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q92876	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q96IK1-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9BRX2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BAG3	IPI	UniProtKB:Q9H6L5-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Bag3	IPI	UniProtKB:Q8AZK7	Mouse	MGI:MGI:5583013|PMID:18457437
Molecular Function	GO:0005515	protein binding	Bag3	IPI	PR:P17879	Mouse	PMID:11527400
Molecular Function	GO:0005515	protein binding	Bag3	IPI	PR:Q9JK92	Mouse	PMID:20060297
Molecular Function	GO:0005515	protein binding	Bag3	IPI	PR:P63017	Mouse	PMID:20060297
Molecular Function	GO:0044877	protein-containing complex binding	Bag3	IDA		Mouse	PMID:20884878
Molecular Function	GO:0044877	protein-containing complex binding	Bag3	IPI	RGD:628878,RGD:2192	Rat	PMID:21561597|RGD:5687132
Molecular Function	GO:0051087	protein-folding chaperone binding	BAG3	IPI	UniProtKB:Q9UJY1	Human	PMID:18006506
Cellular Component	GO:0005737	cytoplasm	BAG3	IDA		Human	PMID:26159920
Cellular Component	GO:0005829	cytosol	BAG3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	BAG3	IDA		Human	PMID:10597216
Cellular Component	GO:0043005	neuron projection	Bag3	IDA		Rat	PMID:18818513|RGD:2325846
Cellular Component	GO:0005654	nucleoplasm	BAG3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	BAG3	IDA		Human	PMID:26159920
Cellular Component	GO:0101031	protein folding chaperone complex	BAG3	IDA		Human	PMID:18006506
Cellular Component	GO:0001725	stress fiber	Bag3	IDA		Rat	PMID:23434281|RGD:12793031
Cellular Component	GO:0030018	Z disc	Bag3	IDA		Mouse	PMID:16936253
Cellular Component	GO:0030018	Z disc	Bag3	IDA		Mouse	PMID:20060297
Cellular Component	GO:0030018	Z disc	bag3	IDA		Zfish	PMID:25866181
Biological Process	GO:0000045	autophagosome assembly	Bag3	IMP		Rat	PMID:23434281|RGD:12793031
Biological Process	GO:0007420	brain development	Bag3	IEP		Rat	PMID:19415333|RGD:2325845
Biological Process	GO:0034605	cellular response to heat	BAG3	IDA		Human	PMID:26159920
Biological Process	GO:0071260	cellular response to mechanical stimulus	Bag3	IMP	MGI:MGI:3530294	Mouse	PMID:16936253
Biological Process	GO:0034620	cellular response to unfolded protein	BAG3	IMP		Human	PMID:18006506
Biological Process	GO:0061684	chaperone-mediated autophagy	Bag3	IMP		Rat	PMID:23434281|RGD:12793031
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	Bag3	IDA		Mouse	PMID:11527400
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	BAG3	IDA		Human	PMID:10597216
Biological Process	GO:0060047	heart contraction	bag3	IMP	ZFIN:ZDB-MRPHLNO-110321-7	Zfish	PMID:21353195
Biological Process	GO:0060047	heart contraction	bag3	IMP	ZFIN:ZDB-MRPHLNO-110321-6	Zfish	PMID:21353195
Biological Process	GO:0007626	locomotory behavior	bag3	IMP	ZFIN:ZDB-MRPHLNO-110321-7	Zfish	PMID:25866181
Biological Process	GO:0046716	muscle cell cellular homeostasis	BAG3	IMP		Human	PMID:19085932
Biological Process	GO:0046716	muscle cell cellular homeostasis	Bag3	IMP		Mouse	MGI:MGI:3656163|PMID:16936253
Biological Process	GO:0043066	negative regulation of apoptotic process	Bag3	IMP		Rat	PMID:21561597|RGD:5687132
Biological Process	GO:1903215	negative regulation of protein targeting to mitochondrion	Bag3	IMP		Rat	PMID:21561597|RGD:5687132
Biological Process	GO:0010664	negative regulation of striated muscle cell apoptotic process	BAG3	IMP		Human	PMID:19085932
Biological Process	GO:0010664	negative regulation of striated muscle cell apoptotic process	Bag3	IMP	MGI:MGI:3530294	Mouse	PMID:16936253
Biological Process	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress	BAG3	IMP		Human	PMID:26159920
Biological Process	GO:1905337	positive regulation of aggrephagy	BAG3	IMP		Human	PMID:18006506
Biological Process	GO:0046827	positive regulation of protein export from nucleus	BAG3	IMP		Human	PMID:26159920
Biological Process	GO:0042307	positive regulation of protein import into nucleus	BAG3	IMP		Human	PMID:26159920
Biological Process	GO:0050821	protein stabilization	BAG3	IDA		Human	PMID:18006506
Biological Process	GO:0050821	protein stabilization	Bag3	IMP	MGI:MGI:3530294	Mouse	PMID:20884878
Biological Process	GO:0007519	skeletal muscle tissue development	bag3	IMP	ZFIN:ZDB-MRPHLNO-110321-7	Zfish	PMID:25866181
Biological Process	GO:0021510	spinal cord development	Bag3	IEP		Rat	PMID:19415333|RGD:2325845
Biological Process	GO:0010658	striated muscle cell apoptotic process	Bag3	IMP	MGI:MGI:3530294	Mouse	PMID:16936253

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern