Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BANK1
  • Mouse genes Bank1
  • Rat genes Bank1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bank1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043274	phospholipase binding	BANK1	IPI	UniProtKB:P16885	Human	PMID:23555801
Molecular Function	GO:0002020	protease binding	BANK1	IPI	UniProtKB:Q9Y4P1	Human	PMID:23555801
Molecular Function	GO:0005515	protein binding	BANK1	IPI	UniProtKB:P07948	Human	PMID:11782428
Molecular Function	GO:0005515	protein binding	BANK1	IPI	UniProtKB:P51451	Human	PMID:21978998
Molecular Function	GO:0005515	protein binding	BANK1	IPI	UniProtKB:P07602	Human	PMID:23555801
Molecular Function	GO:0005515	protein binding	BANK1	IPI	UniProtKB:P12956	Human	PMID:23555801
Molecular Function	GO:0005515	protein binding	Bank1	IPI	UniProtKB:P42227	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:1990782	protein tyrosine kinase binding	BANK1	IPI	UniProtKB:P07948	Human	PMID:11782428
Molecular Function	GO:1990782	protein tyrosine kinase binding	BANK1	IPI	UniProtKB:P06241	Human	PMID:23555801
Molecular Function	GO:1990782	protein tyrosine kinase binding	BANK1	IPI	UniProtKB:P07948	Human	PMID:23555801
Molecular Function	GO:0035591	signaling adaptor activity	BANK1	IDA		Human	PMID:23555801
Molecular Function	GO:0005102	signaling receptor binding	BANK1	IPI	UniProtKB:Q14571	Human	PMID:11782428
Molecular Function	GO:0005102	signaling receptor binding	BANK1	IPI	UniProtKB:Q86VB7	Human	PMID:23555801
Cellular Component	GO:0048471	perinuclear region of cytoplasm	BANK1	IDA		Human	PMID:23555801
Biological Process	GO:0042113	B cell activation	BANK1	IDA		Human	PMID:11782428
Biological Process	GO:0032635	interleukin-6 production	Bank1	IMP	MGI:MGI:3686872	Mouse	PMID:24227780
Biological Process	GO:0000165	MAPK cascade	Bank1	IMP	MGI:MGI:3686872	Mouse	PMID:24227780
Biological Process	GO:0050869	negative regulation of B cell activation	Bank1	IGI	MGI:MGI:88336	Mouse	PMID:16546095
Biological Process	GO:0032715	negative regulation of interleukin-6 production	Bank1	IMP	MGI:MGI:3686872	Mouse	PMID:24227780
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	Bank1	IGI	MGI:MGI:88336	Mouse	PMID:16546095
Biological Process	GO:0045947	negative regulation of translational initiation	Bank1	IMP	MGI:MGI:3686872	Mouse	PMID:24227780
Biological Process	GO:0043410	positive regulation of MAPK cascade	Bank1	IMP	MGI:MGI:3686872	Mouse	PMID:24227780
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	BANK1	IMP		Human	PMID:11782428
Biological Process	GO:0043491	protein kinase B signaling	Bank1	IGI	MGI:MGI:88336	Mouse	PMID:16546095
Biological Process	GO:0009617	response to bacterium	Bank1	IEP		Mouse	PMID:23012479

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern