Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BBC3
  • Mouse genes Bbc3
  • Rat genes Bbc3
  • Zfish genes bbc3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bbc3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	BBC3	IPI	UniProtKB:P11142	Human	PMID:26212789
Molecular Function	GO:0005515	protein binding	BBC3	IPI	UniProtKB:O14920	Human	PMID:26212789
Molecular Function	GO:0005515	protein binding	BBC3	IPI	UniProtKB:P13473	Human	PMID:26212789
Molecular Function	GO:0005515	protein binding	BBC3	IPI	UniProtKB:O14561	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BBC3	IPI	UniProtKB:O14964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BBC3	IPI	UniProtKB:P61964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BBC3	IPI	UniProtKB:Q5TD97	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BBC3	IPI	UniProtKB:Q7Z4V0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BBC3	IPI	UniProtKB:Q7Z5P4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BBC3	IPI	UniProtKB:Q86VE0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BBC3	IPI	UniProtKB:Q8TF42	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Bbc3	IPI	UniProtKB:Q07440	Mouse	MGI:MGI:5926046|PMID:18462686
Molecular Function	GO:0005515	protein binding	Bbc3	IPI	UniProtKB:Q07817-1	Mouse	MGI:MGI:3603103|PMID:16151013
Molecular Function	GO:0005515	protein binding	Bbc3	IPI	UniProtKB:P97287	Mouse	MGI:MGI:4939122|PMID:18589438
Molecular Function	GO:0005515	protein binding	Bbc3	IPI	UniProtKB:Q62881	Rat	PMID:17998337|RGD:10047225
Molecular Function	GO:0005515	protein binding	Bbc3	IPI	RGD:2192	Rat	PMID:19095966|RGD:2313994
Molecular Function	GO:0005515	protein binding	Bbc3	IPI	RGD:2200	Rat	PMID:19095966|RGD:2313994
Cellular Component	GO:0005764	lysosome	BBC3	IDA		Human	PMID:26212789
Cellular Component	GO:0005739	mitochondrion	Bbc3	IDA		Rat	PMID:17127418|RGD:2314141
Cellular Component	GO:0005739	mitochondrion	Bbc3	IDA		Rat	PMID:19095966|RGD:2313994
Biological Process	GO:0006915	apoptotic process	BBC3	IMP		Human	PMID:26212789
Biological Process	GO:0007420	brain development	Bbc3	IEP		Rat	PMID:18058945|RGD:5128576
Biological Process	GO:0071479	cellular response to ionizing radiation	Bbc3	IGI	MGI:MGI:1096393	Mouse	PMID:16286009
Biological Process	GO:0071479	cellular response to ionizing radiation	Bbc3	IGI	MGI:MGI:98834	Mouse	PMID:16286009
Biological Process	GO:0071479	cellular response to ionizing radiation	bbc3	IGI	ZFIN:ZDB-GENE-000616-1	Zfish	PMID:24516599
Biological Process	GO:0008340	determination of adult lifespan	Bbc3	IGI	UniProtKB:P02340	Mouse	MGI:MGI:4944151|PMID:20818388
Biological Process	GO:0006974	DNA damage response	Bbc3	IGI	UniProtKB:P02340	Mouse	MGI:MGI:4944151|PMID:20818388
Biological Process	GO:0044346	fibroblast apoptotic process	Bbc3	IMP	MGI:MGI:2681654	Mouse	PMID:14500851
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Bbc3	IMP	MGI:MGI:2681654	Mouse	PMID:16151013
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Bbc3	IMP		Mouse	MGI:MGI:5448480|PMID:22761832
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Bbc3	IMP		Mouse	MGI:MGI:5621265|PMID:16407291
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Bbc3	IMP		Mouse	MGI:MGI:4879048|PMID:21159964
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	bbc3	IMP	ZFIN:ZDB-MRPHLNO-080809-2	Zfish	PMID:21920315
Biological Process	GO:0070227	lymphocyte apoptotic process	Bbc3	IMP	MGI:MGI:2681654	Mouse	PMID:14500851
Biological Process	GO:0043065	positive regulation of apoptotic process	bbc3	IDA		Zfish	PMID:16888646
Biological Process	GO:0043065	positive regulation of apoptotic process	bbc3	IMP	ZFIN:ZDB-MRPHLNO-080809-2	Zfish	PMID:18510930
Biological Process	GO:2001056	positive regulation of cysteine-type endopeptidase activity	Bbc3	IMP		Mouse	MGI:MGI:4879048|PMID:21159964
Biological Process	GO:2001056	positive regulation of cysteine-type endopeptidase activity	Bbc3	IMP		Mouse	MGI:MGI:5448480|PMID:22761832
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	bbc3	IMP	ZFIN:ZDB-MRPHLNO-070126-5	Zfish	PMID:16888646
Biological Process	GO:2000271	positive regulation of fibroblast apoptotic process	Bbc3	IMP	MGI:MGI:2681654	Mouse	PMID:14500851
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	Bbc3	IMP		Rat	PMID:27031958|RGD:14390051
Biological Process	GO:0070230	positive regulation of lymphocyte apoptotic process	Bbc3	IMP	MGI:MGI:2681654	Mouse	PMID:14500851
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Bbc3	IMP		Mouse	MGI:MGI:5448480|PMID:22761832
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Bbc3	IMP		Mouse	MGI:MGI:4879048|PMID:21159964
Biological Process	GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	Bbc3	IMP	MGI:MGI:2681654	Mouse	PMID:16705087
Biological Process	GO:0070234	positive regulation of T cell apoptotic process	Bbc3	IMP	MGI:MGI:2681654	Mouse	PMID:16832056
Biological Process	GO:0070245	positive regulation of thymocyte apoptotic process	Bbc3	IGI	UniProtKB:P02340	Mouse	MGI:MGI:4944151|PMID:20818388
Biological Process	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	Bbc3	IMP	MGI:MGI:2681654	Mouse	PMID:16705087
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Bbc3	IDA		Mouse	MGI:MGI:4879048|PMID:21159964
Biological Process	GO:0070231	T cell apoptotic process	Bbc3	IMP	MGI:MGI:2681654	Mouse	PMID:16832056
Biological Process	GO:1901998	toxin transport	Bbc3	IMP		Mouse	PMID:23716698

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern