Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BBS2
  • Mouse genes Bbs2
  • Rat genes Bbs2
  • Zfish genes bbs2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bbs2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:P61289	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q9BUN5	Human	PMID:16327777
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q3SYG4	Human	PMID:17574030
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q8IWZ6	Human	PMID:17574030
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q8NFJ9	Human	PMID:17574030
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:P05062	Human	PMID:18000879
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:P68104	Human	PMID:18000879
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q15154	Human	PMID:18000879
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q9NRI5	Human	PMID:18762586
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q3SYG4	Human	PMID:20080638
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q8IWZ6	Human	PMID:20080638
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q9NPJ1	Human	PMID:20080638
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q3SYG4	Human	PMID:22139371
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q3SYG4	Human	PMID:22500027
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q8IWZ6	Human	PMID:22500027
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q8NFJ9	Human	PMID:22500027
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q9NPJ1	Human	PMID:22500027
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:P61289	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q93062	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q99750	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q15051	Human	PMID:25552655
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q3SYG4	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q8IWZ6	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q8NFJ9	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q8IWZ6	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q3SYG4	Human	PMID:29039417
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q8IWZ6-2	Human	PMID:29039417
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:P52597	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:P61289	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:P61968	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q16656-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q53EP0-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q99750	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BBS2	IPI	UniProtKB:Q9Y238	Human	PMID:33144677
Molecular Function	GO:0005515	protein binding	Bbs2	IPI	PR:Q8BMD2	Mouse	PMID:27979967
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	BBS2	IPI	UniProtKB:Q99496	Human	PMID:22302990
Cellular Component	GO:0034464	BBSome	BBS2	IPI		Human	PMID:19081074
Cellular Component	GO:0034464	BBSome	BBS2	IDA		Human	PMID:17574030
Cellular Component	GO:0034464	BBSome	BBS2	IDA		Human	PMID:24550735
Cellular Component	GO:0034464	BBSome	Bbs2	IDA		Mouse	MGI:MGI:5560383|PMID:24550735
Cellular Component	GO:0034464	BBSome	Bbs2	IDA		Mouse	PMID:20080638
Cellular Component	GO:0034464	BBSome	Bbs2	IDA		Mouse	PMID:22500027
Cellular Component	GO:0034464	BBSome	Bbs2	IDA		Mouse	PMID:22072986
Cellular Component	GO:0036064	ciliary basal body	BBS2	IDA		Human	PMID:18299575
Cellular Component	GO:0060170	ciliary membrane	BBS2	IDA		Human	PMID:19081074
Cellular Component	GO:0016020	membrane	Bbs2	IDA		Mouse	PMID:22139371
Cellular Component	GO:0005902	microvillus	Bbs2	IDA		Mouse	PMID:25605782
Cellular Component	GO:0031514	motile cilium	BBS2	IDA		Human	PMID:18299575
Cellular Component	GO:0031514	motile cilium	Bbs2	IMP		Mouse	MGI:MGI:3776933|PMID:18299575
Cellular Component	GO:0043005	neuron projection	Bbs2	IDA		Mouse	PMID:25605782
Cellular Component	GO:0032420	stereocilium	Bbs2	IDA		Mouse	PMID:25605782
Biological Process	GO:0030534	adult behavior	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:15539463
Biological Process	GO:0014824	artery smooth muscle contraction	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:20852044
Biological Process	GO:0048854	brain morphogenesis	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:18032602
Biological Process	GO:0051216	cartilage development	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:19195025
Biological Process	GO:0021987	cerebral cortex development	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:18032602
Biological Process	GO:0060271	cilium assembly	Bbs2	IMP		Mouse	MGI:MGI:3776933|PMID:18299575
Biological Process	GO:0060271	cilium assembly	bbs2	IMP		Zfish	PMID:16399798|ZFIN:ZDB-PUB-060124-4
Biological Process	GO:0060271	cilium assembly	bbs2	IMP	ZFIN:ZDB-MRPHLNO-060209-3	Zfish	PMID:16399798
Biological Process	GO:0007368	determination of left/right symmetry	bbs2	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-081027-1	Zfish	PMID:18381349
Biological Process	GO:0007368	determination of left/right symmetry	bbs2	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-081027-3	Zfish	PMID:18381349
Biological Process	GO:0007368	determination of left/right symmetry	bbs2	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-060519-1	Zfish	PMID:18381349
Biological Process	GO:0007368	determination of left/right symmetry	bbs2	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-060209-5	Zfish	PMID:18381349
Biological Process	GO:0045444	fat cell differentiation	Bbs2	IEP		Mouse	MGI:MGI:3794016|PMID:17379567
Biological Process	GO:0007369	gastrulation	bbs2	IMP	ZFIN:ZDB-MRPHLNO-131205-1	Zfish	PMID:20498079
Biological Process	GO:0010467	gene expression	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:19150989
Biological Process	GO:0010467	gene expression	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:18317593
Biological Process	GO:0043001	Golgi to plasma membrane protein transport	BBS2	IMP		Human	PMID:19150989
Biological Process	GO:0021766	hippocampus development	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:18032602
Biological Process	GO:0046907	intracellular transport	bbs2	IMP	ZFIN:ZDB-MRPHLNO-060209-3	Zfish	PMID:16399798
Biological Process	GO:0070121	Kupffer's vesicle development	bbs2	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-060209-5	Zfish	PMID:18381349
Biological Process	GO:0070121	Kupffer's vesicle development	bbs2	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-081027-3	Zfish	PMID:18381349
Biological Process	GO:0070121	Kupffer's vesicle development	bbs2	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-081027-1	Zfish	PMID:18381349
Biological Process	GO:0070121	Kupffer's vesicle development	bbs2	IMP	ZFIN:ZDB-MRPHLNO-060209-3	Zfish	PMID:16399798
Biological Process	GO:0070121	Kupffer's vesicle development	bbs2	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-060519-1	Zfish	PMID:18381349
Biological Process	GO:0033210	leptin-mediated signaling pathway	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:19150989
Biological Process	GO:0032402	melanosome transport	bbs2	IMP		Zfish	PMID:16399798|ZFIN:ZDB-PUB-060124-4
Biological Process	GO:0032402	melanosome transport	bbs2	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-060209-5	Zfish	PMID:18381349
Biological Process	GO:0032402	melanosome transport	bbs2	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-081027-1	Zfish	PMID:18381349
Biological Process	GO:0032402	melanosome transport	bbs2	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-081027-3	Zfish	PMID:18381349
Biological Process	GO:0032402	melanosome transport	bbs2	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-060519-1	Zfish	PMID:18381349
Biological Process	GO:0032402	melanosome transport	bbs2	IMP	ZFIN:ZDB-MRPHLNO-060209-3	Zfish	PMID:16399798
Biological Process	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway	Bbs2	IMP		Mouse	MGI:MGI:3836843|PMID:19150989
Biological Process	GO:0010629	negative regulation of gene expression	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:18317593
Biological Process	GO:0010629	negative regulation of gene expression	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:19150989
Biological Process	GO:0040015	negative regulation of multicellular organism growth	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:15539463
Biological Process	GO:1905515	non-motile cilium assembly	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:19195025
Biological Process	GO:0045494	photoreceptor cell maintenance	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:15539463
Biological Process	GO:0045494	photoreceptor cell maintenance	bbs2	IMP	ZFIN:ZDB-GENO-210812-5	Zfish	PMID:33324636
Biological Process	GO:0051877	pigment granule aggregation in cell center	bbs2	IMP	ZFIN:ZDB-MRPHLNO-060209-3	Zfish	PMID:16399798
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:18317593
Biological Process	GO:0008104	protein localization	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:15539463
Biological Process	GO:0008104	protein localization	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:22228099
Biological Process	GO:0033365	protein localization to organelle	Bbs2	IDA		Mouse	MGI:MGI:3778303|PMID:18334641
Biological Process	GO:0060296	regulation of cilium beat frequency involved in ciliary motility	Bbs2	IMP		Mouse	MGI:MGI:3776933|PMID:18299575
Biological Process	GO:0042478	regulation of eye photoreceptor cell development	bbs2	IMP	ZFIN:ZDB-GENO-210812-5	Zfish	PMID:33324636
Biological Process	GO:0044321	response to leptin	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:18317593
Biological Process	GO:0007288	sperm axoneme assembly	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:15539463
Biological Process	GO:0021756	striatum development	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:18032602
Biological Process	GO:0042311	vasodilation	Bbs2	IMP	MGI:MGI:3521669	Mouse	PMID:20852044
Biological Process	GO:0007601	visual perception	BBS2	IMP		Human	PMID:25541840

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern