Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BCHE
  • Mouse genes Bche
  • Rat genes Bche
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bche

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003990	acetylcholinesterase activity	Bche	IDA		Mouse	MGI:MGI:4418611|PMID:17212694
Molecular Function	GO:0033265	choline binding	Bche	IDA		Rat	PMID:1133098|RGD:2301187
Molecular Function	GO:0033265	choline binding	Bche	IDA		Rat	PMID:126256|RGD:2301195
Molecular Function	GO:0004104	cholinesterase activity	BCHE	IDA		Human	PMID:19452557
Molecular Function	GO:0004104	cholinesterase activity	Bche	IDA		Rat	PMID:1133098|RGD:2301187
Molecular Function	GO:0004104	cholinesterase activity	Bche	IDA		Rat	PMID:126256|RGD:2301195
Molecular Function	GO:0004104	cholinesterase activity	Bche	IDA		Rat	PMID:16519684|RGD:1599453
Molecular Function	GO:0042802	identical protein binding	BCHE	IPI	UniProtKB:P06276	Human	PMID:17660298
Molecular Function	GO:0042802	identical protein binding	BCHE	IPI	UniProtKB:P06276	Human	PMID:20883446
Molecular Function	GO:0042802	identical protein binding	BCHE	IPI	UniProtKB:P06276	Human	PMID:21059932
Molecular Function	GO:0042802	identical protein binding	BCHE	IPI	UniProtKB:P06276	Human	PMID:22726956
Molecular Function	GO:0005515	protein binding	BCHE	IPI	UniProtKB:P67812	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCHE	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BCHE	IPI	UniProtKB:O75190-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BCHE	IPI	UniProtKB:O75400-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BCHE	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BCHE	IPI	UniProtKB:P46379-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BCHE	IPI	UniProtKB:P54252	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BCHE	IPI	UniProtKB:P55212	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BCHE	IPI	UniProtKB:P62826	Human	PMID:32814053
Cellular Component	GO:0072562	blood microparticle	BCHE	HDA		Human	PMID:22516433
Cellular Component	GO:0005783	endoplasmic reticulum	Bche	IDA		Mouse	PMID:8651510
Cellular Component	GO:0005788	endoplasmic reticulum lumen	Bche	IDA		Rat	PMID:1133098|RGD:2301187
Cellular Component	GO:0005615	extracellular space	Bche	IDA		Rat	PMID:17194019|RGD:1599446
Cellular Component	GO:0016020	membrane	Bche	IDA		Rat	PMID:12379509|RGD:2306781
Cellular Component	GO:0005641	nuclear envelope lumen	Bche	IDA		Mouse	PMID:8651510
Biological Process	GO:0019695	choline metabolic process	Bche	IDA		Rat	PMID:1133098|RGD:2301187
Biological Process	GO:0019695	choline metabolic process	Bche	IDA		Rat	PMID:126256|RGD:2301195
Biological Process	GO:0007612	learning	Bche	IDA		Rat	PMID:16275899|RGD:1599456
Biological Process	GO:0008285	negative regulation of cell population proliferation	Bche	IMP		Rat	PMID:21771623|RGD:5688134
Biological Process	GO:0050805	negative regulation of synaptic transmission	Bche	IDA		Rat	PMID:16275899|RGD:1599456
Biological Process	GO:0014016	neuroblast differentiation	Bche	IMP		Rat	PMID:21771623|RGD:5688134
Biological Process	GO:0043279	response to alkaloid	Bche	IDA		Rat	PMID:17159811|RGD:1599448
Biological Process	GO:0051593	response to folic acid	Bche	IDA		Rat	PMID:16442260|RGD:1599454
Biological Process	GO:0051384	response to glucocorticoid	Bche	IDA		Rat	PMID:16179131|RGD:1599459
Biological Process	GO:0007584	response to nutrient	Bche	IDA		Rat	PMID:15002734|RGD:1599460
Biological Process	GO:0009410	response to xenobiotic stimulus	Bche	IDA		Rat	PMID:16572919|RGD:1599452

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern