Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BCL10
  • Mouse genes Bcl10
  • Rat genes Bcl10
  • Zfish genes bcl10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bcl10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050700	CARD domain binding	Bcl10	IPI	UniProtKB:A2AIV8	Mouse	MGI:MGI:5310700|PMID:22265677
Molecular Function	GO:0140296	general transcription initiation factor binding	BCL10	IPI	UniProtKB:Q00403	Human	PMID:15207693
Molecular Function	GO:0042802	identical protein binding	BCL10	IPI	UniProtKB:O95999	Human	PMID:10187771
Molecular Function	GO:0042802	identical protein binding	BCL10	IPI	UniProtKB:O95999	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	BCL10	IPI	UniProtKB:O95999	Human	PMID:32296183
Molecular Function	GO:0042802	identical protein binding	Bcl10	IPI	UniProtKB:Q9Z0H7	Mouse	MGI:MGI:3694380|PMID:16831874
Molecular Function	GO:0019209	kinase activator activity	BCL10	IDA		Human	PMID:15125833
Molecular Function	GO:0051059	NF-kappaB binding	BCL10	IDA		Human	PMID:16280327
Molecular Function	GO:0002020	protease binding	BCL10	IPI	UniProtKB:Q9UDY8	Human	PMID:18223652
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q66677	Human	PMID:10187771
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q15628	Human	PMID:1040062
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9H257	Human	PMID:11053425
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9BWT7	Human	PMID:11259443
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9BXL6	Human	PMID:11278692
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9BXL7	Human	PMID:11278692
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q12933	Human	PMID:11466612
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9NPP4	Human	PMID:11472070
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9BXL7	Human	PMID:12154360
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:P61088	Human	PMID:14695475
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9UDY8	Human	PMID:14695475
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:P20749	Human	PMID:16280327
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:P31749	Human	PMID:16280327
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9BXL7	Human	PMID:16809782
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:P51617-1	Human	PMID:16831874
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9UQM7	Human	PMID:17052756
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9Y6K9	Human	PMID:17363905
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9BXL7	Human	PMID:17948050
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9UDY8	Human	PMID:17948050
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9Y6K9	Human	PMID:18287044
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9BXL7	Human	PMID:19118383
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9UDY8	Human	PMID:19118383
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9BXL7	Human	PMID:19444310
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9UDY8	Human	PMID:19444310
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9BXL7	Human	PMID:19815501
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9BXL7	Human	PMID:21157432
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9UDY8	Human	PMID:21157432
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9H257	Human	PMID:22267217
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9UDY8	Human	PMID:22267217
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9BXL7	Human	PMID:22528498
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9UDY8	Human	PMID:22528498
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:P31749	Human	PMID:24412244
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q05513	Human	PMID:25011391
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q12933	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9H257	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q12933	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9H257	Human	PMID:26488816
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9UDY8	Human	PMID:27070702
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9Y6K9	Human	PMID:27070702
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9Y2V7	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9BXL7	Human	PMID:31296852
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9H257	Human	PMID:31296852
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9UDY8	Human	PMID:31774199
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL10	IPI	UniProtKB:Q9Y2V7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Bcl10	IPI	UniProtKB:Q66677	Mouse	MGI:MGI:1334920|PMID:10187771
Molecular Function	GO:0005515	protein binding	Bcl10	IPI	UniProtKB:Q66677	Mouse	MGI:MGI:5795828|PMID:11238466
Molecular Function	GO:0005515	protein binding	Bcl10	IPI	PR:Q8BST6	Mouse	PMID:15213237
Molecular Function	GO:0005515	protein binding	Bcl10	IPI	PR:Q2TBA3	Mouse	PMID:16495340
Molecular Function	GO:0005515	protein binding	Bcl10	IPI	RGD:1321367	Rat	PMID:10753917|RGD:631970
Molecular Function	GO:0043422	protein kinase B binding	BCL10	IPI	UniProtKB:P31749	Human	PMID:16280327
Molecular Function	GO:0043621	protein self-association	BCL10	IPI	UniProtKB:O95999	Human	PMID:15125833
Molecular Function	GO:0043621	protein self-association	BCL10	IDA		Human	PMID:24074955
Molecular Function	GO:0044877	protein-containing complex binding	Bcl10	IPI	RGD:1310457|RGD:621282	Rat	PMID:12786973|RGD:2298728
Molecular Function	GO:0003713	transcription coactivator activity	BCL10	IDA		Human	PMID:15207693
Molecular Function	GO:0031625	ubiquitin protein ligase binding	BCL10	IPI	UniProtKB:Q13489	Human	PMID:16395405
Cellular Component	GO:0032449	CBM complex	BCL10	IDA		Human	PMID:24074955
Cellular Component	GO:0032449	CBM complex	BCL10	IDA		Human	PMID:28628108
Cellular Component	GO:0032449	CBM complex	Bcl10	IDA		Mouse	MGI:MGI:5310700|PMID:22265677
Cellular Component	GO:0032449	CBM complex	bcl10	IDA		Zfish	PMID:25849213
Cellular Component	GO:0005737	cytoplasm	BCL10	IDA		Human	PMID:11021819
Cellular Component	GO:0005737	cytoplasm	BCL10	IDA		Human	PMID:11053425
Cellular Component	GO:0005737	cytoplasm	BCL10	IDA		Human	PMID:11238466
Cellular Component	GO:0005737	cytoplasm	BCL10	IDA		Human	PMID:11278692
Cellular Component	GO:0005737	cytoplasm	BCL10	IDA		Human	PMID:15082780
Cellular Component	GO:0005737	cytoplasm	Bcl10	IDA		Mouse	PMID:12867038
Cellular Component	GO:0005737	cytoplasm	bcl10	IDA		Zfish	PMID:25849213
Cellular Component	GO:0005881	cytoplasmic microtubule	BCL10	IDA		Human	PMID:23264731
Cellular Component	GO:0005829	cytosol	BCL10	IDA		Human	PMID:12154360
Cellular Component	GO:0005829	cytosol	BCL10	IDA		Human	PMID:16831874
Cellular Component	GO:0005829	cytosol	Bcl10	IDA		Mouse	MGI:MGI:3694380|PMID:16831874
Cellular Component	GO:0005829	cytosol	Bcl10	IDA		Rat	PMID:10725326|RGD:1581901
Cellular Component	GO:0001772	immunological synapse	Bcl10	IDA		Mouse	PMID:14724296
Cellular Component	GO:0005764	lysosome	BCL10	IDA		Human	PMID:15082780
Cellular Component	GO:0045121	membrane raft	Bcl10	IDA		Mouse	PMID:12867038
Cellular Component	GO:0005634	nucleus	BCL10	IDA		Human	PMID:16280327
Cellular Component	GO:0048471	perinuclear region of cytoplasm	BCL10	IDA		Human	PMID:16127295
Cellular Component	GO:0002096	polkadots	Bcl10	IDA		Mouse	MGI:MGI:3656456|PMID:16495340
Cellular Component	GO:0032991	protein-containing complex	BCL10	IDA		Human	PMID:14695475
Cellular Component	GO:0032991	protein-containing complex	BCL10	IDA		Human	PMID:16280327
Cellular Component	GO:0032991	protein-containing complex	BCL10	IDA		Human	PMID:22267217
Cellular Component	GO:0032991	protein-containing complex	Bcl10	IDA		Rat	PMID:12786973|RGD:2298728
Biological Process	GO:0002250	adaptive immune response	BCL10	IMP		Human	PMID:25365219
Biological Process	GO:0061760	antifungal innate immune response	Bcl10	IDA		Mouse	MGI:MGI:5310700|PMID:22265677
Biological Process	GO:0001783	B cell apoptotic process	Bcl10	IDA		Mouse	PMID:10753917
Biological Process	GO:0008219	cell death	BCL10	IDA		Human	PMID:10400625
Biological Process	GO:0006968	cellular defense response	Bcl10	IMP	MGI:MGI:2158304	Mouse	PMID:11163238
Biological Process	GO:0071222	cellular response to lipopolysaccharide	BCL10	IEP		Human	PMID:16831874
Biological Process	GO:0071260	cellular response to mechanical stimulus	BCL10	IEP		Human	PMID:19593445
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Bcl10	IMP	MGI:MGI:2158304	Mouse	PMID:11163238
Biological Process	GO:0016064	immunoglobulin mediated immune response	Bcl10	IMP	MGI:MGI:2158304	Mouse	PMID:11163238
Biological Process	GO:0045087	innate immune response	BCL10	IEP		Human	PMID:16831874
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	BCL10	IDA		Human	PMID:16831874
Biological Process	GO:0002906	negative regulation of mature B cell apoptotic process	BCL10	IDA		Human	PMID:15878976
Biological Process	GO:0001843	neural tube closure	Bcl10	IMP		Mouse	MGI:MGI:1930354|PMID:11163238
Biological Process	GO:0043065	positive regulation of apoptotic process	BCL10	IDA		Human	PMID:11821383
Biological Process	GO:0043065	positive regulation of apoptotic process	Bcl10	IDA		Rat	PMID:10753917|RGD:631970
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	BCL10	IMP		Human	PMID:22267217
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Bcl10	IDA		Mouse	PMID:10753917
Biological Process	GO:0001819	positive regulation of cytokine production	Bcl10	IDA		Mouse	MGI:MGI:5310700|PMID:22265677
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	BCL10	IDA		Human	PMID:15207693
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	BCL10	IDA		Human	PMID:11466612
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	Bcl10	IDA		Mouse	PMID:10753917
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	BCL10	IEP		Human	PMID:12761501
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	BCL10	IDA		Human	PMID:18287044
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	BCL10	IDA		Human	PMID:27777308
Biological Process	GO:0032757	positive regulation of interleukin-8 production	BCL10	IMP		Human	PMID:17095757
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	BCL10	IDA		Human	PMID:10400625
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	BCL10	IDA		Human	PMID:14695475
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	BCL10	IDA		Human	PMID:18287044
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	BCL10	IDA		Human	PMID:24074955
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	BCL10	IDA		Human	PMID:27777308
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Bcl10	IDA		Mouse	MGI:MGI:5310700|PMID:22265677
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	bcl10	IDA		Zfish	PMID:25849213
Biological Process	GO:0042327	positive regulation of phosphorylation	BCL10	IDA		Human	PMID:15125833
Biological Process	GO:0031398	positive regulation of protein ubiquitination	BCL10	IDA		Human	PMID:14695475
Biological Process	GO:0050870	positive regulation of T cell activation	Bcl10	IMP	MGI:MGI:2158304	Mouse	PMID:14614861
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	BCL10	IDA		Human	PMID:18287044
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	BCL10	IDA		Human	PMID:27777308
Biological Process	GO:0051260	protein homooligomerization	BCL10	IDA		Human	PMID:24074955
Biological Process	GO:0050856	regulation of T cell receptor signaling pathway	Bcl10	IMP	MGI:MGI:2158304	Mouse	PMID:14614861
Biological Process	GO:0032094	response to food	BCL10	IDA		Human	PMID:17095757
Biological Process	GO:0009620	response to fungus	Bcl10	IMP	MGI:MGI:2158304	Mouse	PMID:16862125
Biological Process	GO:0070231	T cell apoptotic process	Bcl10	IDA		Mouse	PMID:10753917
Biological Process	GO:0050852	T cell receptor signaling pathway	BCL10	IDA		Human	PMID:15125833
Biological Process	GO:0002224	toll-like receptor signaling pathway	BCL10	IDA		Human	PMID:16831874

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern