Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BCL2L2,BCL2L2-PABPN1
  • Mouse genes Bcl2l2
  • Rat genes Bcl2l2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bcl2l2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051400	BH domain binding	Bcl2l2	IPI	RGD:2192	Rat	PMID:9356461|RGD:70678
Molecular Function	GO:0051400	BH domain binding	Bcl2l2	IPI	RGD:621547	Rat	PMID:9356461|RGD:70678
Molecular Function	GO:0051400	BH domain binding	Bcl2l2	IPI	RGD:621635	Rat	PMID:9356461|RGD:70678
Molecular Function	GO:0097718	disordered domain specific binding	BCL2L2	IPI	UniProtKB:O54918	Human	PMID:16645638
Molecular Function	GO:0042802	identical protein binding	BCL2L2	IPI	UniProtKB:Q92843	Human	PMID:22000515
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:O43521	Human	PMID:15694340
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:P55957	Human	PMID:15694340
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q13323	Human	PMID:15694340
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q91ZE9	Human	PMID:15694340
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q92934	Human	PMID:15694340
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q9BXH1	Human	PMID:15694340
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:O43521	Human	PMID:16697956
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:P55957	Human	PMID:16697956
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q13323	Human	PMID:16697956
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q91ZE9	Human	PMID:16697956
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q9BXH1	Human	PMID:16697956
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:O43521	Human	PMID:17289999
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:P55957	Human	PMID:17289999
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q07812	Human	PMID:17289999
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:P59635	Human	PMID:17428862
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q13625	Human	PMID:18448430
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q13625	Human	PMID:18719108
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q07812	Human	PMID:18981409
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:O43521	Human	PMID:21199865
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q07812	Human	PMID:21199865
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q92934	Human	PMID:22000515
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q7L3V2	Human	PMID:23055042
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:P15884	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q13323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q16611	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q8N6L0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q969F0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q96LC9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q13323	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q8IYF3-3	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q8N6L0	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q9BXH1	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:O43521	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:O95470	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:O95471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:P02654	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:P0C671	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:P11912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:P15941-11	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:P18859	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:P27105	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:P27469	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:P48051	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:P55056	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:P60508	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q13323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q13433-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q16611	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q5T7V8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q68DC2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q6NTF9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q7RTU4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q7Z4F1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q7Z769	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q7Z7N9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q8IV31	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q8IYJ2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q8N5K1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q8N6L0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q8TDV0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q8TED1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q92915-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q92934	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q969F0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q96L08	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q96LC9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q96RD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q99735	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q9H3N1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q9H9P2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q9NP94	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q9NQQ7-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q9NR31	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q9UHD4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L2	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Bcl2l2	IPI	UniProtKB:Q0VBL6	Mouse	MGI:MGI:5526927|PMID:21546903
Molecular Function	GO:0005515	protein binding	Bcl2l2	IPI	PR:Q61337	Mouse	PMID:12115603
Molecular Function	GO:0005515	protein binding	Bcl2l2	IPI	PR:Q91ZE9	Mouse	PMID:11546872
Molecular Function	GO:0005515	protein binding	Bcl2l2	IPI	PR:P62137	Mouse	PMID:12115603
Molecular Function	GO:0005515	protein binding	Bcl2l2	IPI	PR:O54918	Mouse	PMID:16645638
Molecular Function	GO:0005515	protein binding	Bcl2l2	IPI	RGD:728296|RGD:728344	Rat	PMID:15159385|RGD:1302732
Molecular Function	GO:0044877	protein-containing complex binding	Bcl2l2	IPI	RGD:2192	Rat	PMID:9356461|RGD:70678
Molecular Function	GO:0044877	protein-containing complex binding	Bcl2l2	IPI	RGD:621547	Rat	PMID:9356461|RGD:70678
Molecular Function	GO:0044877	protein-containing complex binding	Bcl2l2	IPI	RGD:621635	Rat	PMID:9356461|RGD:70678
Cellular Component	GO:0097136	Bcl-2 family protein complex	BCL2L2	IPI		Human	PMID:15694340
Cellular Component	GO:0097136	Bcl-2 family protein complex	BCL2L2	IMP		Human	PMID:16645638
Cellular Component	GO:0005737	cytoplasm	Bcl2l2	IDA		Rat	PMID:10724126|RGD:14394498
Cellular Component	GO:0005737	cytoplasm	Bcl2l2	IDA		Rat	PMID:15341589|RGD:1581915
Cellular Component	GO:0005829	cytosol	Bcl2l2	IDA		Mouse	PMID:11980919
Cellular Component	GO:0031966	mitochondrial membrane	Bcl2l2	IDA		Mouse	PMID:11980919
Cellular Component	GO:0031966	mitochondrial membrane	Bcl2l2	IDA		Rat	PMID:10724126|RGD:14394498
Cellular Component	GO:0005739	mitochondrion	Bcl2l2	IDA		Rat	PMID:15341589|RGD:1581915
Biological Process	GO:0006915	apoptotic process	Bcl2l2	IMP		Rat	PMID:18817839|RGD:2313963
Biological Process	GO:0007420	brain development	Bcl2l2	IEP		Rat	PMID:10366024|RGD:632002
Biological Process	GO:0071230	cellular response to amino acid stimulus	Bcl2l2	IEP		Rat	PMID:11090983|RGD:14394513
Biological Process	GO:1904646	cellular response to amyloid-beta	Bcl2l2	IEP		Rat	PMID:17287517|RGD:14394420
Biological Process	GO:0071392	cellular response to estradiol stimulus	Bcl2l2	IEP		Rat	PMID:17287517|RGD:14394420
Biological Process	GO:1905430	cellular response to glycine	Bcl2l2	IEP		Rat	PMID:11090983|RGD:14394513
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	Bcl2l2	IDA		Mouse	PMID:12115603
Biological Process	GO:0043066	negative regulation of apoptotic process	BCL2L2	IMP		Human	PMID:17289999
Biological Process	GO:0035795	negative regulation of mitochondrial membrane permeability	Bcl2l2	IDA		Rat	PMID:10724126|RGD:14394498
Biological Process	GO:0090201	negative regulation of release of cytochrome c from mitochondria	Bcl2l2	IDA		Rat	PMID:10724126|RGD:14394498
Biological Process	GO:0042981	regulation of apoptotic process	BCL2L2	IDA		Human	PMID:16697956
Biological Process	GO:0002931	response to ischemia	Bcl2l2	IEP		Rat	PMID:10724126|RGD:14394498
Biological Process	GO:0060011	Sertoli cell proliferation	Bcl2l2	IGI	MGI:MGI:99702	Mouse	PMID:11784036

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern