Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BCL3
  • Mouse genes Bcl3
  • Rat genes Bcl3
  • Zfish genes bcl3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bcl3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140297	DNA-binding transcription factor binding	BCL3	IPI	UniProtKB:Q04206	Human	PMID:11387332
Molecular Function	GO:0140297	DNA-binding transcription factor binding	BCL3	IPI	UniProtKB:P19838	Human	PMID:16108830
Molecular Function	GO:0140297	DNA-binding transcription factor binding	BCL3	IPI	UniProtKB:Q00653	Human	PMID:16108830
Molecular Function	GO:0140297	DNA-binding transcription factor binding	BCL3	IPI	UniProtKB:P19838	Human	PMID:16306601
Molecular Function	GO:0140297	DNA-binding transcription factor binding	BCL3	IPI	UniProtKB:P40763	Human	PMID:16306601
Molecular Function	GO:0140297	DNA-binding transcription factor binding	BCL3	IPI	UniProtKB:P42224	Human	PMID:16306601
Molecular Function	GO:0140297	DNA-binding transcription factor binding	BCL3	IPI	UniProtKB:P19838	Human	PMID:8196632
Molecular Function	GO:0042826	histone deacetylase binding	BCL3	IPI	UniProtKB:Q13547	Human	PMID:16306601
Molecular Function	GO:0005515	protein binding	BCL3	IPI	UniProtKB:O00625	Human	PMID:10362352
Molecular Function	GO:0005515	protein binding	BCL3	IPI	UniProtKB:P06239	Human	PMID:16099425
Molecular Function	GO:0005515	protein binding	BCL3	IPI	UniProtKB:O95999	Human	PMID:16280327
Molecular Function	GO:0005515	protein binding	BCL3	IPI	UniProtKB:P56545	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	BCL3	IPI	UniProtKB:Q9BVL2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Bcl3	IPI	UniProtKB:Q80TQ2	Mouse	MGI:MGI:3624874|PMID:16713561
Molecular Function	GO:0005515	protein binding	Bcl3	IPI	UniProtKB:Q80TQ2	Mouse	MGI:MGI:4820954|PMID:19893491
Molecular Function	GO:0005515	protein binding	Bcl3	IPI	UniProtKB:Q86UW6	Mouse	MGI:MGI:3710720|PMID:12730195
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	BCL3	IDA		Human	PMID:16306601
Molecular Function	GO:0003713	transcription coactivator activity	Bcl3	IDA		Mouse	PMID:16081776
Molecular Function	GO:0003714	transcription corepressor activity	BCL3	IDA		Human	PMID:16306601
Cellular Component	GO:0032996	Bcl3-Bcl10 complex	BCL3	IDA		Human	PMID:16280327
Cellular Component	GO:0033257	Bcl3/NF-kappaB2 complex	BCL3	IDA		Human	PMID:9407099
Cellular Component	GO:0005737	cytoplasm	BCL3	IDA		Human	PMID:11387332
Cellular Component	GO:0005829	cytosol	BCL3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	BCL3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030496	midbody	BCL3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	BCL3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	BCL3	IDA		Human	PMID:16280327
Cellular Component	GO:0005634	nucleus	BCL3	IDA		Human	PMID:16306601
Cellular Component	GO:0005634	nucleus	BCL3	IDA		Human	PMID:8196632
Cellular Component	GO:0005886	plasma membrane	BCL3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032991	protein-containing complex	BCL3	IDA		Human	PMID:16280327
Biological Process	GO:0019730	antimicrobial humoral response	Bcl3	IMP	MGI:MGI:1861796	Mouse	PMID:9009202
Biological Process	GO:0042742	defense response to bacterium	Bcl3	IMP	MGI:MGI:1861796	Mouse	PMID:9009202
Biological Process	GO:0042832	defense response to protozoan	Bcl3	IMP	MGI:MGI:1861796	Mouse	PMID:9009202
Biological Process	GO:0006974	DNA damage response	BCL3	IDA		Human	PMID:16384933
Biological Process	GO:0030330	DNA damage response, signal transduction by p53 class mediator	BCL3	IMP		Human	PMID:16384933
Biological Process	GO:0030198	extracellular matrix organization	Bcl3	IMP	MGI:MGI:2158443	Mouse	PMID:10586052
Biological Process	GO:0002268	follicular dendritic cell differentiation	Bcl3	IMP	MGI:MGI:2158443	Mouse	PMID:10586052
Biological Process	GO:0002467	germinal center formation	Bcl3	IMP	MGI:MGI:1861796	Mouse	PMID:9009202
Biological Process	GO:0002467	germinal center formation	Bcl3	IMP	MGI:MGI:2158443	Mouse	PMID:10586052
Biological Process	GO:0002467	germinal center formation	Bcl3	IMP	MGI:MGI:2158443	Mouse	PMID:9133427
Biological Process	GO:0002455	humoral immune response mediated by circulating immunoglobulin	Bcl3	IMP	MGI:MGI:1861796	Mouse	PMID:9009202
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	BCL3	IDA		Human	PMID:8196632
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	BCL3	IMP		Human	PMID:16384933
Biological Process	GO:0002315	marginal zone B cell differentiation	Bcl3	IMP	MGI:MGI:1861796	Mouse	PMID:9009202
Biological Process	GO:0043066	negative regulation of apoptotic process	BCL3	IDA		Human	PMID:16384933
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	BCL3	IDA		Human	PMID:16306601
Biological Process	GO:0032717	negative regulation of interleukin-8 production	BCL3	IMP		Human	PMID:16306601
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	BCL3	IDA		Human	PMID:16306601
Biological Process	GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	BCL3	IMP		Human	PMID:16306601
Biological Process	GO:0070233	negative regulation of T cell apoptotic process	Bcl3	IGI	MGI:MGI:1197519	Mouse	PMID:16832056
Biological Process	GO:0070233	negative regulation of T cell apoptotic process	Bcl3	IMP		Mouse	PMID:16832056
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	Bcl3	IMP		Mouse	PMID:15465827
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	BCL3	IDA		Human	PMID:16384933
Biological Process	GO:0032733	positive regulation of interleukin-10 production	Bcl3	IMP		Mouse	PMID:15465827
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bcl3	IDA		Mouse	PMID:16081776
Biological Process	GO:0045727	positive regulation of translation	BCL3	IMP		Human	PMID:16384933
Biological Process	GO:0032729	positive regulation of type II interferon production	Bcl3	IMP	MGI:MGI:2158443	Mouse	PMID:16790793
Biological Process	GO:0006606	protein import into nucleus	BCL3	IDA		Human	PMID:8196632
Biological Process	GO:0042981	regulation of apoptotic process	BCL3	IDA		Human	PMID:16732314
Biological Process	GO:0051101	regulation of DNA binding	BCL3	IEP		Human	PMID:9407099
Biological Process	GO:1901222	regulation of NIK/NF-kappaB signaling	BCL3	IEP		Human	PMID:8196632
Biological Process	GO:0048545	response to steroid hormone	bcl3	IEP		Zfish	PMID:28265462
Biological Process	GO:0010225	response to UV-C	BCL3	IDA		Human	PMID:16384933
Biological Process	GO:0009615	response to virus	BCL3	IDA		Human	PMID:16306601
Biological Process	GO:0048536	spleen development	Bcl3	IMP	MGI:MGI:2158443	Mouse	PMID:10586052
Biological Process	GO:0070231	T cell apoptotic process	Bcl3	IGI	MGI:MGI:1197519	Mouse	PMID:16832056
Biological Process	GO:0070231	T cell apoptotic process	Bcl3	IMP		Mouse	PMID:16832056
Biological Process	GO:0042088	T-helper 1 type immune response	Bcl3	IMP	MGI:MGI:1861796	Mouse	PMID:9009202
Biological Process	GO:0045064	T-helper 2 cell differentiation	Bcl3	IMP	MGI:MGI:2158443	Mouse	PMID:16081776
Biological Process	GO:0032609	type II interferon production	Bcl3	IMP	MGI:MGI:2158443	Mouse	PMID:16790793

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern