Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BCO2
  • Mouse genes Bco2
  • Rat genes Bco2
  • Zfish genes bco2a,bco2b,bco2l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bco2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0010437	9,10 (9', 10')-carotenoid-cleaving dioxygenase activity	bco2l	IDA		Zfish	PMID:22764054
Molecular Function	GO:0102076	beta,beta-carotene-9',10'-cleaving oxygenase activity	Bco2	IDA		Mouse	MGI:MGI:2159483|PMID:11278918
Molecular Function	GO:0102076	beta,beta-carotene-9',10'-cleaving oxygenase activity	Bco2	IDA		Mouse	MGI:MGI:4947204|PMID:21106934
Molecular Function	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	BCO2	IDA		Human	PMID:11278918
Molecular Function	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	BCO2	IDA		Human	PMID:21302131
Molecular Function	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	Bco2	IDA		Mouse	MGI:MGI:2159483|PMID:11278918
Molecular Function	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	Bco2	IDA		Mouse	MGI:MGI:4947204|PMID:21106934
Cellular Component	GO:0005739	mitochondrion	Bco2	IDA		Mouse	MGI:MGI:4947204|PMID:21106934
Cellular Component	GO:0005739	mitochondrion	bco2l	IDA		Zfish	PMID:22764054
Biological Process	GO:0016121	carotene catabolic process	BCO2	IDA		Human	PMID:21302131
Biological Process	GO:0016121	carotene catabolic process	Bco2	IDA		Mouse	MGI:MGI:4947204|PMID:21106934
Biological Process	GO:0016121	carotene catabolic process	Bco2	IDA		Mouse	MGI:MGI:2159483|PMID:11278918
Biological Process	GO:0016119	carotene metabolic process	BCO2	IDA		Human	PMID:11278918
Biological Process	GO:0016119	carotene metabolic process	Bco2	IDA		Mouse	MGI:MGI:2159483|PMID:11278918
Biological Process	GO:0016116	carotenoid metabolic process	Bco2	IMP		Mouse	MGI:MGI:4947204|PMID:21106934
Biological Process	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	bco2l	IMP	ZFIN:ZDB-MRPHLNO-120817-2	Zfish	PMID:22764054
Biological Process	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	bco2l	IMP	ZFIN:ZDB-MRPHLNO-120817-1	Zfish	PMID:22764054
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	Bco2	IMP		Mouse	MGI:MGI:4947204|PMID:21106934
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	Bco2	IMP		Mouse	MGI:MGI:4947204|PMID:21106934
Biological Process	GO:0042574	retinal metabolic process	Bco2	IGI	MGI:MGI:1926923	Mouse	PMID:25701869
Biological Process	GO:0016124	xanthophyll catabolic process	Bco2	IDA		Mouse	MGI:MGI:4947204|PMID:21106934
Biological Process	GO:0016122	xanthophyll metabolic process	Bco2	IMP	MGI:MGI:4840382	Mouse	PMID:25701869

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern