Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BDH2
  • Mouse genes Bdh2
  • Rat genes Bdh2
  • Zfish genes bdh2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bdh2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003858	3-hydroxybutyrate dehydrogenase activity	BDH2	IDA		Human	PMID:16380372
Molecular Function	GO:0051287	NAD binding	BDH2	IDA		Human	PMID:16380372
Molecular Function	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	Bdh2	IMP		Mouse	MGI:MGI:4820913|PMID:20550936
Molecular Function	GO:0005515	protein binding	BDH2	IPI	UniProtKB:Q13952-2	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	BDH2	IDA		Human	PMID:16380372
Cellular Component	GO:0005829	cytosol	BDH2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	BDH2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	BDH2	HDA		Human	PMID:23533145
Biological Process	GO:0030855	epithelial cell differentiation	BDH2	IDA		Human	PMID:21492153
Biological Process	GO:0043249	erythrocyte maturation	bdh2	IMP	ZFIN:ZDB-MRPHLNO-100624-6	Zfish	PMID:26929344
Biological Process	GO:0006635	fatty acid beta-oxidation	BDH2	IDA		Human	PMID:16380372
Biological Process	GO:0042168	heme metabolic process	bdh2	IMP		Zfish	PMID:20550936|ZFIN:ZDB-PUB-100621-25
Biological Process	GO:0042541	hemoglobin biosynthetic process	bdh2	IMP	ZFIN:ZDB-MRPHLNO-100624-6	Zfish	PMID:20550936
Biological Process	GO:0042541	hemoglobin biosynthetic process	bdh2	IMP	ZFIN:ZDB-MRPHLNO-100624-6	Zfish	PMID:26929344
Biological Process	GO:0006880	intracellular sequestering of iron ion	Bdh2	IMP		Mouse	MGI:MGI:4820913|PMID:20550936
Biological Process	GO:0019290	siderophore biosynthetic process	Bdh2	IMP		Mouse	MGI:MGI:4820913|PMID:20550936

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern