Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BDKRB1
  • Mouse genes Bdkrb1
  • Rat genes Bdkrb1
  • Zfish genes bdkrb1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bdkrb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004947	bradykinin receptor activity	BDKRB1	IDA		Human	PMID:10422787
Molecular Function	GO:0004947	bradykinin receptor activity	BDKRB1	IDA		Human	PMID:1314587
Molecular Function	GO:0004947	bradykinin receptor activity	Bdkrb1	IDA		Rat	PMID:12025968|RGD:727669
Molecular Function	GO:0004947	bradykinin receptor activity	bdkrb1	IMP		Zfish	PMID:15891034
Molecular Function	GO:0004947	bradykinin receptor activity	bdkrb1	IDA		Zfish	PMID:12049646
Molecular Function	GO:0042277	peptide binding	Bdkrb1	IDA		Mouse	PMID:8602848
Molecular Function	GO:0042277	peptide binding	Bdkrb1	IPI	PubChem_Substance:682521	Rat	PMID:10422787|RGD:1625744
Molecular Function	GO:0005515	protein binding	BDKRB1	IPI	UniProtKB:P01042:PRO_0000006687	Human	PMID:23597562
Cellular Component	GO:0016020	membrane	Bdkrb1	IDA		Rat	PMID:10422787|RGD:1625744
Cellular Component	GO:0043005	neuron projection	Bdkrb1	IDA		Rat	PMID:12927641|RGD:1579989
Cellular Component	GO:0005886	plasma membrane	Bdkrb1	IDA		Rat	PMID:14515994|RGD:1625769
Biological Process	GO:0016477	cell migration	Bdkrb1	IMP		Rat	PMID:20411591|RGD:5129223
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	bdkrb1	IMP		Zfish	PMID:15891034|ZFIN:ZDB-PUB-050518-6
Biological Process	GO:0006954	inflammatory response	Bdkrb1	IMP		Rat	PMID:12411434|RGD:628496
Biological Process	GO:0045776	negative regulation of blood pressure	Bdkrb1	IMP		Rat	PMID:15253105|RGD:1625759
Biological Process	GO:0045776	negative regulation of blood pressure	Bdkrb1	IMP		Rat	PMID:16507603|RGD:1625747
Biological Process	GO:0030308	negative regulation of cell growth	Bdkrb1	IMP		Rat	PMID:16497153|RGD:1625749
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Bdkrb1	IMP		Rat	PMID:16497153|RGD:1625749
Biological Process	GO:0002687	positive regulation of leukocyte migration	Bdkrb1	IMP		Rat	PMID:12522068|RGD:704380
Biological Process	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	Bdkrb1	IDA		Rat	PMID:15576455|RGD:1625040
Biological Process	GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	Bdkrb1	IDA		Rat	PMID:15319421|RGD:1625754
Biological Process	GO:0032496	response to lipopolysaccharide	Bdkrb1	IDA		Mouse	PMID:8602848
Biological Process	GO:0032496	response to lipopolysaccharide	Bdkrb1	IEP		Rat	PMID:19561153|RGD:5129225
Biological Process	GO:0019233	sensory perception of pain	Bdkrb1	IMP		Rat	PMID:12927641|RGD:1579989

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern