Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BDKRB2
  • Mouse genes Bdkrb2
  • Rat genes Bdkrb2
  • Zfish genes bdkrb2,si:dkey-63b1.1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bdkrb2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031698	beta-2 adrenergic receptor binding	Bdkrb2	IPI	RGD:2060	Rat	PMID:20150590|RGD:8548534
Molecular Function	GO:0004947	bradykinin receptor activity	BDKRB2	IDA		Human	PMID:1314587
Molecular Function	GO:0004947	bradykinin receptor activity	BDKRB2	IDA		Human	PMID:1329734
Molecular Function	GO:0004947	bradykinin receptor activity	BDKRB2	IDA		Human	PMID:17077303
Molecular Function	GO:0004947	bradykinin receptor activity	Bdkrb2	IDA		Rat	PMID:1715575|RGD:631709
Molecular Function	GO:0002020	protease binding	BDKRB2	IPI	UniProtKB:P12821	Human	PMID:17077303
Molecular Function	GO:0005515	protein binding	BDKRB2	IPI	UniProtKB:P16284	Human	PMID:18672896
Molecular Function	GO:0005515	protein binding	BDKRB2	IPI	UniProtKB:P01042:PRO_0000006688	Human	PMID:23597562
Molecular Function	GO:0005515	protein binding	Bdkrb2	IPI	RGD:731747	Rat	PMID:12177051|RGD:1625039
Molecular Function	GO:0005515	protein binding	Bdkrb2	IPI	RGD:3347	Rat	PMID:15607753|RGD:1625041
Molecular Function	GO:0005515	protein binding	Bdkrb2	IPI	RGD:2072	Rat	PMID:16754789|RGD:1625043
Molecular Function	GO:0046982	protein heterodimerization activity	BDKRB2	IPI	UniProtKB:P30556	Human	PMID:10993080
Molecular Function	GO:0031702	type 1 angiotensin receptor binding	BDKRB2	IPI	UniProtKB:P30556	Human	PMID:10993080
Cellular Component	GO:0005768	endosome	BDKRB2	IDA		Human	PMID:17077303
Cellular Component	GO:0005794	Golgi apparatus	BDKRB2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	BDKRB2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	BDKRB2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	BDKRB2	IDA		Human	PMID:17077303
Cellular Component	GO:0005886	plasma membrane	Bdkrb2	IDA		Rat	PMID:16754789|RGD:1625043
Biological Process	GO:0002438	acute inflammatory response to antigenic stimulus	Bdkrb2	IMP		Rat	PMID:7791078|RGD:4891025
Biological Process	GO:0050482	arachidonic acid secretion	BDKRB2	IDA		Human	PMID:17077303
Biological Process	GO:0071456	cellular response to hypoxia	Bdkrb2	IEP		Rat	PMID:19565561|RGD:4891057
Biological Process	GO:1990127	intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	Bdkrb2	IGI	MGI:MGI:98834	Mouse	PMID:16571598
Biological Process	GO:1990127	intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	Bdkrb2	IGI	MGI:MGI:99702	Mouse	PMID:16571598
Biological Process	GO:0035633	maintenance of blood-brain barrier	Bdkrb2	IDA		Rat	PMID:20080302|RGD:4891047
Biological Process	GO:0045776	negative regulation of blood pressure	Bdkrb2	IMP		Rat	PMID:16507603|RGD:1625747
Biological Process	GO:0008285	negative regulation of cell population proliferation	Bdkrb2	IMP		Rat	PMID:12177051|RGD:1625039
Biological Process	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	Bdkrb2	IMP	MGI:MGI:1857135	Mouse	PMID:16571598
Biological Process	GO:1902239	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	Bdkrb2	IGI	MGI:MGI:99702	Mouse	PMID:16571598
Biological Process	GO:1902239	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	Bdkrb2	IGI	MGI:MGI:98834	Mouse	PMID:16571598
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	Bdkrb2	IMP	MGI:MGI:1857135	Mouse	PMID:16571598
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Bdkrb2	IMP		Rat	PMID:15576455|RGD:1625040
Biological Process	GO:0009651	response to salt stress	Bdkrb2	IGI	MGI:MGI:98834	Mouse	PMID:16571598
Biological Process	GO:0009651	response to salt stress	Bdkrb2	IGI	MGI:MGI:99702	Mouse	PMID:16571598
Biological Process	GO:0009410	response to xenobiotic stimulus	Bdkrb2	IEP		Rat	PMID:18190998|RGD:2313333
Biological Process	GO:0042311	vasodilation	BDKRB2	IDA		Human	PMID:4322742
Biological Process	GO:0042311	vasodilation	BDKRB2	IDA		Human	PMID:6055465
Biological Process	GO:0042311	vasodilation	Bdkrb2	IMP	MGI:MGI:1857135	Mouse	PMID:11282893

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern