Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BECN2
  • Mouse genes Becn2
  • Rat genes Becn2
  • Zfish genes becn1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Becn2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	BECN2	IPI	UniProtKB:Q5JY77	Human	PMID:23954414
Molecular Function	GO:0005515	protein binding	BECN2	IPI	UniProtKB:Q6ZNE5	Human	PMID:23954414
Molecular Function	GO:0005515	protein binding	BECN2	IPI	UniProtKB:Q8NEB9	Human	PMID:23954414
Molecular Function	GO:0005515	protein binding	BECN2	IPI	UniProtKB:Q9C0C7	Human	PMID:23954414
Molecular Function	GO:0005515	protein binding	BECN2	IPI	UniProtKB:Q9P2Y5	Human	PMID:23954414
Molecular Function	GO:0005515	protein binding	Becn2	IPI	PR:Q5U4C1	Mouse	PMID:23954414
Molecular Function	GO:0044877	protein-containing complex binding	Becn2	IDA		Mouse	PMID:23954414
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	becn1	IMP	ZFIN:ZDB-GENO-210225-5	Zfish	PMID:32102330
Biological Process	GO:0006914	autophagy	BECN2	IMP		Human	PMID:23954414
Biological Process	GO:0006914	autophagy	Becn2	IMP	MGI:MGI:5550535	Mouse	PMID:23954414
Biological Process	GO:0006914	autophagy	becn1	IMP	ZFIN:ZDB-MRPHLNO-151021-2	Zfish	PMID:24441423
Biological Process	GO:0006914	autophagy	becn1	IMP	ZFIN:ZDB-MRPHLNO-161128-3,ZFIN:ZDB-MRPHLNO-161128-4	Zfish	PMID:27467399
Biological Process	GO:0006914	autophagy	becn1	IGI	ZFIN:ZDB-MRPHLNO-081229-2,ZFIN:ZDB-MRPHLNO-141015-1	Zfish	PMID:24967584
Biological Process	GO:0090398	cellular senescence	becn1	IGI	ZFIN:ZDB-GENO-141104-6,ZFIN:ZDB-MRPHLNO-141015-1	Zfish	PMID:24967584
Biological Process	GO:0090398	cellular senescence	becn1	IGI	ZFIN:ZDB-MRPHLNO-081229-2,ZFIN:ZDB-MRPHLNO-141015-1	Zfish	PMID:24967584
Biological Process	GO:0008333	endosome to lysosome transport	BECN2	IMP		Human	PMID:23954414
Biological Process	GO:0008333	endosome to lysosome transport	Becn2	IMP		Mouse	MGI:MGI:5528919|PMID:23954414
Biological Process	GO:1990172	G protein-coupled receptor catabolic process	BECN2	IPI	UniProtKB:Q5JY77	Human	PMID:23954414
Biological Process	GO:1990172	G protein-coupled receptor catabolic process	BECN2	IMP		Human	PMID:23954414
Biological Process	GO:1990172	G protein-coupled receptor catabolic process	Becn2	IMP	MGI:MGI:5550535	Mouse	PMID:23954414
Biological Process	GO:0042593	glucose homeostasis	Becn2	IGI	MGI:MGI:104615	Mouse	PMID:23954414
Biological Process	GO:0007507	heart development	becn1	IMP	ZFIN:ZDB-MRPHLNO-151021-2	Zfish	PMID:24441423
Biological Process	GO:0007507	heart development	becn1	IMP	ZFIN:ZDB-MRPHLNO-151021-5	Zfish	PMID:24441423
Biological Process	GO:0043416	regulation of skeletal muscle tissue regeneration	becn1	IMP	ZFIN:ZDB-MRPHLNO-161128-3,ZFIN:ZDB-MRPHLNO-161128-4	Zfish	PMID:27467399

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern