Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BGLAP
  • Mouse genes Bglap2
  • Rat genes Bglap
  • Zfish genes bglapl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bglap2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046848	hydroxyapatite binding	Bglap2	IDA		Mouse	PMID:17693256
Molecular Function	GO:0005515	protein binding	BGLAP	IPI	UniProtKB:Q12797-6	Human	PMID:32296183
Molecular Function	GO:0008147	structural constituent of bone	Bglap	IDA		Rat	PMID:19854502|RGD:2316154
Cellular Component	GO:0042995	cell projection	Bglap	IDA		Rat	PMID:3262606|RGD:2316180
Cellular Component	GO:0005737	cytoplasm	BGLAP	IDA		Human	PMID:11856645
Cellular Component	GO:0005737	cytoplasm	Bglap	IDA		Rat	PMID:19688349|RGD:2316153
Cellular Component	GO:0030425	dendrite	Bglap	IDA		Rat	PMID:22552891|RGD:6483318
Cellular Component	GO:0005576	extracellular region	Bglap	IDA		Rat	PMID:15030764|RGD:8553659
Cellular Component	GO:0005615	extracellular space	Bglap2	IDA		Mouse	PMID:17693256
Cellular Component	GO:0005615	extracellular space	Bglap	IDA		Rat	PMID:18758911|RGD:2301841
Cellular Component	GO:0005615	extracellular space	Bglap	IDA		Rat	PMID:21893222|RGD:151667428
Cellular Component	GO:0005615	extracellular space	Bglap	IDA		Rat	PMID:22576626|RGD:151667429
Cellular Component	GO:0005794	Golgi apparatus	Bglap	IDA		Rat	PMID:3111671|RGD:2316179
Cellular Component	GO:0043204	perikaryon	Bglap	IDA		Rat	PMID:22552891|RGD:6483318
Cellular Component	GO:0005791	rough endoplasmic reticulum	Bglap	IDA		Rat	PMID:3111671|RGD:2316179
Cellular Component	GO:0031982	vesicle	Bglap	IDA		Rat	PMID:18758911|RGD:2301841
Biological Process	GO:0007568	aging	Bglap	IEP		Rat	PMID:3937585|RGD:6483558
Biological Process	GO:0060348	bone development	Bglap	IEP		Rat	PMID:3488316|RGD:2316176
Biological Process	GO:0044242	cellular lipid catabolic process	Bglap2	IMP	MGI:MGI:2180471	Mouse	PMID:17693256
Biological Process	GO:0071363	cellular response to growth factor stimulus	Bglap	IEP		Rat	PMID:19903460|RGD:2316144
Biological Process	GO:0032869	cellular response to insulin stimulus	Bglap2	IGI	MGI:MGI:106675	Mouse	PMID:17693256
Biological Process	GO:0032869	cellular response to insulin stimulus	Bglap2	IMP	MGI:MGI:2180471	Mouse	PMID:17693256
Biological Process	GO:0071305	cellular response to vitamin D	Bglap	IEP		Rat	PMID:3257212|RGD:6483560
Biological Process	GO:0071305	cellular response to vitamin D	Bglap	IEP		Rat	PMID:6607920|RGD:2316174
Biological Process	GO:0034224	cellular response to zinc ion starvation	Bglap	IEP		Rat	PMID:21893222|RGD:151667428
Biological Process	GO:0016311	dephosphorylation	Bglap	IDA		Rat	PMID:21893222|RGD:151667428
Biological Process	GO:0016311	dephosphorylation	Bglap	IDA		Rat	PMID:22576626|RGD:151667429
Biological Process	GO:0042593	glucose homeostasis	Bglap2	IMP	MGI:MGI:2180471	Mouse	PMID:17693256
Biological Process	GO:0042476	odontogenesis	Bglap	IEP		Rat	PMID:3497183|RGD:2316177
Biological Process	GO:0001503	ossification	Bglap	IEP		Rat	PMID:3265336|RGD:1298707
Biological Process	GO:0002076	osteoblast development	Bglap	IEP		Rat	PMID:20020468|RGD:2316141
Biological Process	GO:0001649	osteoblast differentiation	BGLAP	IEP		Human	PMID:17023519
Biological Process	GO:0001649	osteoblast differentiation	Bglap	IEP		Rat	PMID:20022632|RGD:2316140
Biological Process	GO:0031016	pancreas development	Bglap2	IMP	MGI:MGI:2180471	Mouse	PMID:17693256
Biological Process	GO:0032024	positive regulation of insulin secretion	Bglap2	IMP	MGI:MGI:2180471	Mouse	PMID:17693256
Biological Process	GO:0014823	response to activity	Bglap	IEP		Rat	PMID:20029737|RGD:2316139
Biological Process	GO:0043627	response to estrogen	Bglap	IEP		Rat	PMID:19577454|RGD:2316165
Biological Process	GO:0045471	response to ethanol	Bglap	IEP		Rat	PMID:19330277|RGD:2316172
Biological Process	GO:0051384	response to glucocorticoid	Bglap	IEP		Rat	PMID:19966384|RGD:2316142
Biological Process	GO:0009629	response to gravity	Bglap	IEP		Rat	PMID:19774112|RGD:2316152
Biological Process	GO:0033594	response to hydroxyisoflavone	Bglap	IEP		Rat	PMID:19695348|RGD:2316151
Biological Process	GO:0010035	response to inorganic substance	Bglap	IEP		Rat	PMID:19915804|RGD:2316143
Biological Process	GO:0032868	response to insulin	Bglap	IEP		Rat	PMID:20818503|RGD:151667419
Biological Process	GO:0036005	response to macrophage colony-stimulating factor	Bglap	IEP		Rat	PMID:7669437|RGD:151665777
Biological Process	GO:0009612	response to mechanical stimulus	Bglap	IEP		Rat	PMID:19472893|RGD:2316168
Biological Process	GO:0031667	response to nutrient levels	Bglap	IEP		Rat	PMID:19668107|RGD:2316163
Biological Process	GO:0014070	response to organic cyclic compound	Bglap	IEP		Rat	PMID:20020468|RGD:2316141
Biological Process	GO:0014070	response to organic cyclic compound	Bglap	IEP		Rat	PMID:20818503|RGD:151667419
Biological Process	GO:0033574	response to testosterone	Bglap	IEP		Rat	PMID:19501680|RGD:2316167
Biological Process	GO:0033280	response to vitamin D	BGLAP	IEP		Human	PMID:17023519
Biological Process	GO:0032571	response to vitamin K	Bglap	IEP		Rat	PMID:21944271|RGD:6483564
Biological Process	GO:0009410	response to xenobiotic stimulus	Bglap	IEP		Rat	PMID:19609736|RGD:2316164
Biological Process	GO:0010043	response to zinc ion	Bglap	IEP		Rat	PMID:19506366|RGD:2316166
Biological Process	GO:0048863	stem cell differentiation	Bglap	IEP		Rat	PMID:19840645|RGD:2316145
Biological Process	GO:0044342	type B pancreatic cell proliferation	Bglap2	IMP	MGI:MGI:2180471	Mouse	PMID:17693256

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern