Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BHLHA15
  • Mouse genes Bhlha15
  • Rat genes Bhlha15
  • Zfish genes bhlha15
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bhlha15

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Bhlha15	IDA		Mouse	PMID:15024058
Molecular Function	GO:0003677	DNA binding	Bhlha15	IDA		Rat	PMID:9073453|RGD:633179
Molecular Function	GO:0003677	DNA binding	Bhlha15	IDA		Rat	PMID:9753324|RGD:633178
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Bhlha15	IMP		Mouse	MGI:MGI:3038031|PMID:15024058
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Bhlha15	IDA		Mouse	MGI:MGI:3038031|PMID:15024058
Molecular Function	GO:0042802	identical protein binding	Bhlha15	IPI	PR:Q9QYC3	Mouse	PMID:15024058
Molecular Function	GO:0005515	protein binding	BHLHA15	IPI	UniProtKB:P15173	Human	PMID:32296183
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Bhlha15	IDA		Mouse	MGI:MGI:3038031|PMID:15024058
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Bhlha15	IMP		Mouse	MGI:MGI:3038031|PMID:15024058
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	BHLHA15	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	Bhlha15	IDA		Mouse	PMID:16423820
Cellular Component	GO:0005634	nucleus	Bhlha15	IDA		Mouse	PMID:12921743
Cellular Component	GO:0005634	nucleus	Bhlha15	IDA		Mouse	PMID:11696558
Cellular Component	GO:0005634	nucleus	Bhlha15	IDA		Rat	PMID:9073453|RGD:633179
Biological Process	GO:0019722	calcium-mediated signaling	Bhlha15	IMP	MGI:MGI:2182768	Mouse	PMID:15665001
Biological Process	GO:0007267	cell-cell signaling	Bhlha15	IMP	MGI:MGI:2182768	Mouse	PMID:12829745
Biological Process	GO:0042149	cellular response to glucose starvation	Bhlha15	IDA		Mouse	MGI:MGI:5607242|PMID:17612490
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	Bhlha15	IDA		Mouse	MGI:MGI:5607242|PMID:17612490
Biological Process	GO:0051649	establishment of localization in cell	Bhlha15	IMP	MGI:MGI:2182768	Mouse	PMID:15665001
Biological Process	GO:0031017	exocrine pancreas development	bhlha15	IMP	ZFIN:ZDB-MRPHLNO-070808-1	Zfish	PMID:17531198
Biological Process	GO:0031017	exocrine pancreas development	bhlha15	IDA		Zfish	PMID:17531198
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Bhlha15	IDA		Mouse	PMID:11696558
Biological Process	GO:0002071	glandular epithelial cell maturation	Bhlha15	IMP		Mouse	PMID:15024058
Biological Process	GO:0042593	glucose homeostasis	Bhlha15	IMP	MGI:MGI:2182768	Mouse	PMID:16423820
Biological Process	GO:0007030	Golgi organization	Bhlha15	IMP	MGI:MGI:2182768	Mouse	PMID:15665001
Biological Process	GO:0048312	intracellular distribution of mitochondria	Bhlha15	IMP	MGI:MGI:2182768	Mouse	PMID:15665001
Biological Process	GO:0006851	mitochondrial calcium ion transmembrane transport	Bhlha15	IMP	MGI:MGI:2182768	Mouse	PMID:15665001
Biological Process	GO:0010832	negative regulation of myotube differentiation	Bhlha15	IDA		Mouse	MGI:MGI:5607242|PMID:17612490
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bhlha15	IMP		Mouse	MGI:MGI:3038031|PMID:15024058
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bhlha15	IDA		Mouse	PMID:15024058
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bhlha15	IDA		Mouse	PMID:12829745
Biological Process	GO:0072560	type B pancreatic cell maturation	Bhlha15	IMP	MGI:MGI:2182768	Mouse	PMID:16423820

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern