Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BICD1
  • Mouse genes Bicd1
  • Rat genes Bicd1
  • Zfish genes bicd1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bicd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008093	cytoskeletal anchor activity	BICD1	IDA		Human	PMID:12447383
Molecular Function	GO:0034452	dynactin binding	BICD1	IDA		Human	PMID:12447383
Molecular Function	GO:0034452	dynactin binding	BICD1	IPI	UniProtKB:Q13561|UniProtKB:Q14203	Human	PMID:17139249
Molecular Function	GO:0070840	dynein complex binding	BICD1	IDA		Human	PMID:12447383
Molecular Function	GO:0045505	dynein intermediate chain binding	BICD1	IDA		Human	PMID:17139249
Molecular Function	GO:0005515	protein binding	BICD1	IPI	UniProtKB:P49841	Human	PMID:17139249
Molecular Function	GO:0005515	protein binding	BICD1	IPI	UniProtKB:P08318	Human	PMID:20089649
Molecular Function	GO:0005515	protein binding	BICD1	IPI	UniProtKB:P40763	Human	PMID:21988832
Molecular Function	GO:0019901	protein kinase binding	BICD1	IPI	UniProtKB:P49841	Human	PMID:17139249
Molecular Function	GO:0031871	proteinase activated receptor binding	Bicd1	IPI	UniProtKB:P25116	Mouse	MGI:MGI:4887309|PMID:20164183
Molecular Function	GO:0031871	proteinase activated receptor binding	Bicd1	IPI	UniProtKB:P25116	Rat	PMID:20164183|RGD:8693367
Molecular Function	GO:0031267	small GTPase binding	BICD1	IPI	UniProtKB:P20340	Human	PMID:12447383
Cellular Component	GO:0005813	centrosome	BICD1	IMP		Human	PMID:17139249
Cellular Component	GO:0005881	cytoplasmic microtubule	BICD1	IDA		Human	PMID:20089649
Cellular Component	GO:0031410	cytoplasmic vesicle	BICD1	IDA		Human	PMID:12447383
Cellular Component	GO:0031410	cytoplasmic vesicle	BICD1	IDA		Human	PMID:20089649
Cellular Component	GO:0005829	cytosol	BICD1	IDA		Human	PMID:12447383
Cellular Component	GO:0005794	Golgi apparatus	BICD1	IDA		Human	PMID:17139249
Cellular Component	GO:0005794	Golgi apparatus	BICD1	IDA		Human	PMID:17562788
Cellular Component	GO:0016020	membrane	BICD1	IDA		Human	PMID:12447383
Cellular Component	GO:0048471	perinuclear region of cytoplasm	BICD1	IMP		Human	PMID:17139249
Cellular Component	GO:0048471	perinuclear region of cytoplasm	BICD1	IDA		Human	PMID:20089649
Cellular Component	GO:0099503	secretory vesicle	BICD1	IDA		Human	PMID:20089649
Cellular Component	GO:0005802	trans-Golgi network	BICD1	IDA		Human	PMID:12447383
Cellular Component	GO:0005802	trans-Golgi network	BICD1	IDA		Human	PMID:20089649
Biological Process	GO:0072393	microtubule anchoring at microtubule organizing center	Bicd1	IMP		Mouse	MGI:MGI:4397616|PMID:19825938
Biological Process	GO:0072385	minus-end-directed organelle transport along microtubule	BICD1	IMP		Human	PMID:12447383
Biological Process	GO:0008045	motor neuron axon guidance	bicd1a	IMP	ZFIN:ZDB-MRPHLNO-180904-1	Zfish	PMID:31541015
Biological Process	GO:0008045	motor neuron axon guidance	bicd1a	IMP	ZFIN:ZDB-GENO-201020-3	Zfish	PMID:31541015
Biological Process	GO:1900275	negative regulation of phospholipase C activity	Bicd1	IDA		Mouse	MGI:MGI:4887309|PMID:20164183
Biological Process	GO:1900737	negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway	Bicd1	IDA		Mouse	MGI:MGI:4887309|PMID:20164183
Biological Process	GO:1900737	negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway	Bicd1	IMP		Rat	PMID:20164183|RGD:8693367
Biological Process	GO:1904781	positive regulation of protein localization to centrosome	BICD1	IGI	UniProtKB:Q8TD16	Human	PMID:17139249
Biological Process	GO:0048260	positive regulation of receptor-mediated endocytosis	BICD1	IMP		Human	PMID:20164183
Biological Process	GO:0033365	protein localization to organelle	BICD1	IDA		Human	PMID:12447383
Biological Process	GO:0033365	protein localization to organelle	BICD1	IDA		Human	PMID:20089649
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	BICD1	IGI	UniProtKB:Q8TD16	Human	PMID:17139249
Biological Process	GO:1900276	regulation of proteinase activated receptor activity	Bicd1	IDA		Mouse	MGI:MGI:4887309|PMID:20164183
Biological Process	GO:2001017	regulation of retrograde axon cargo transport	bicd1a	IMP		Zfish	PMID:31541015
Biological Process	GO:0034063	stress granule assembly	Bicd1	IMP		Mouse	MGI:MGI:4397616|PMID:19825938
Biological Process	GO:0016032	viral process	BICD1	IMP		Human	PMID:20089649

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern