Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BIK
  • Mouse genes Bik
  • Rat genes Bik
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bik

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051400	BH domain binding	Bik	IPI	RGD:2199	Rat	PMID:9356461|RGD:70678
Molecular Function	GO:0051400	BH domain binding	Bik	IPI	RGD:2200	Rat	PMID:9356461|RGD:70678
Molecular Function	GO:0051400	BH domain binding	Bik	IPI	RGD:620525	Rat	PMID:9356461|RGD:70678
Molecular Function	GO:0051400	BH domain binding	Bik	IPI	RGD:620621	Rat	PMID:9356461|RGD:70678
Molecular Function	GO:0051400	BH domain binding	Bik	IPI	RGD:620717	Rat	PMID:9356461|RGD:70678
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q07817-1	Human	PMID:15694340
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q92843	Human	PMID:15694340
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q07817	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:P10415	Human	PMID:16697956
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q07817	Human	PMID:16697956
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q92843	Human	PMID:16697956
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:P10415	Human	PMID:17289999
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q8BHC7-1	Human	PMID:18953687
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q8TEB9-1	Human	PMID:18953687
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:P10415	Human	PMID:20010695
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q969F0	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9HD36	Human	PMID:23235460
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9HD36	Human	PMID:23563182
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q16548	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q92843	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q969F0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:A0A0S2Z3D2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q07817	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q07817	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q92843	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q07817	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q16548	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q969F0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:A5PKU2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:B2RUZ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:O00264	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:O14523	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:O15554	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:O43169	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:O43826	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:O95159	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:O95183	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:O95393	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:O95406	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:P05090	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:P0DN84	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:P10415	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:P12314	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:P17152	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:P19397	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:P21854	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:P26678	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:P49447	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:P60201-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q04941	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q06432	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q07817	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q12983	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q14416	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q15836	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q15848	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q16548	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q2M3D2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q4LDR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q5BJF2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q5BVD1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q5J8X5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q5TGU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q5VZY2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q6PL45-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q6UX40	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q7Z769	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q86W74-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q8IWU4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q8IXM6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q8N511	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q8N661	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q8N6F1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q8N6R1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q8N912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q8NBD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q8TBE1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q8TBM7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q8TED1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q8WVV5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q8WVX3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q8WWP7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q92504	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q92520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q92843	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q969E2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q969F0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q969X1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q96AL5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q96D05-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q96DZ9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q96FZ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q96G79	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q96GQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q96HE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q96IW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9BQB6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9BU79	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9BVK2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9BXJ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9GZR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9H0R3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9H2L4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9H6H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9HD36	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9NVV5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9NX47	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9P0S9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9UHE5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9UHJ9-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9UHX3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9UNK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9Y5U4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9Y5Z9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9Y6D0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q9Y6X1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:Q07817-1	Human	PMID:9027312
Molecular Function	GO:0005515	protein binding	BIK	IPI	UniProtKB:P10415	Human	PMID:9463381
Molecular Function	GO:0005515	protein binding	Bik	IPI	PR:P10417	Mouse	PMID:9525867
Molecular Function	GO:0005515	protein binding	Bik	IPI	PR:Q64373-1	Mouse	PMID:9525867
Molecular Function	GO:0044877	protein-containing complex binding	Bik	IPI	RGD:2199	Rat	PMID:9356461|RGD:70678
Molecular Function	GO:0044877	protein-containing complex binding	Bik	IPI	RGD:2200	Rat	PMID:9356461|RGD:70678
Molecular Function	GO:0044877	protein-containing complex binding	Bik	IPI	RGD:620525	Rat	PMID:9356461|RGD:70678
Molecular Function	GO:0044877	protein-containing complex binding	Bik	IPI	RGD:620621	Rat	PMID:9356461|RGD:70678
Molecular Function	GO:0044877	protein-containing complex binding	Bik	IPI	RGD:620717	Rat	PMID:9356461|RGD:70678
Cellular Component	GO:0097136	Bcl-2 family protein complex	BIK	IPI		Human	PMID:15694340
Cellular Component	GO:0005740	mitochondrial envelope	Bik	IDA		Mouse	PMID:9525867
Biological Process	GO:0008637	apoptotic mitochondrial changes	Bik	IDA		Mouse	PMID:9525867
Biological Process	GO:0008584	male gonad development	Bik	IGI	MGI:MGI:1197519	Mouse	PMID:16270031
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	BIK	IDA		Human	PMID:21041309
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	BIK	IDA		Human	PMID:21041309
Biological Process	GO:0042981	regulation of apoptotic process	BIK	IDA		Human	PMID:16697956
Biological Process	GO:0007283	spermatogenesis	Bik	IGI	MGI:MGI:1197519	Mouse	PMID:16270031

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern