Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BIRC2
  • Mouse genes Birc2
  • Rat genes Birc2
  • Zfish genes birc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Birc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0098770	FBXO family protein binding	BIRC2	IPI	UniProtKB:Q9Y3I1	Human	PMID:16510124
Molecular Function	GO:0042802	identical protein binding	BIRC2	IPI	UniProtKB:Q13490	Human	PMID:22493164
Molecular Function	GO:0042802	identical protein binding	BIRC2	IPI	UniProtKB:Q13490	Human	PMID:30561431
Molecular Function	GO:0042802	identical protein binding	BIRC2	IPI	UniProtKB:Q13490	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P55210	Human	PMID:11084335
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P55211	Human	PMID:11084335
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q12933	Human	PMID:11907583
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q13077	Human	PMID:11907583
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:O15392	Human	PMID:15665297
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q12933	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q12933	Human	PMID:16282325
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q9NR28	Human	PMID:16282325
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:O00220|UniProtKB:O14763|UniProtKB:P25445	Human	PMID:18846110
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P49841	Human	PMID:18846110
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P55211	Human	PMID:19153467
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q9NR28	Human	PMID:19153467
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q12933	Human	PMID:20447407
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q13077	Human	PMID:20447407
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q12933	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q9BZW7	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q9NP84	Human	PMID:21525013
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q01094	Human	PMID:21653699
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q12933	Human	PMID:21653699
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:O94966	Human	PMID:21849505
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:O43353	Human	PMID:21931591
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P57078	Human	PMID:21931591
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q13546	Human	PMID:21931591
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q9Y572	Human	PMID:21931591
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q12933	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q13077	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P63000	Human	PMID:22117219
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q12933	Human	PMID:23524849
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q13077	Human	PMID:23524849
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q96FW1	Human	PMID:23524849
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P55211	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q12933	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P08949	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P14136	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P55211	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q8N3J5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q96CA5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q96CJ1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q96CN9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q96HA8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q9BZW7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q9NQT4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q9Y3E2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P07900	Human	PMID:25486457
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P08238	Human	PMID:25486457
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P08949-2	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q13077	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q96CA5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q96HA8	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q12933	Human	PMID:30561431
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q13077	Human	PMID:30561431
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q13546	Human	PMID:30561431
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P55211	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q96CA5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q96HA8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q9Y3E2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:A0A087WZT3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:O60341	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P08949-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P40937	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P51451	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P51813	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:P55211	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q06455-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q8N3J5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q96CN9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q9NQT4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q9UBU9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q9Y3E2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q9Y4C2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BIRC2	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Birc2	IPI	PR:Q01721	Mouse	PMID:11906213
Molecular Function	GO:0044877	protein-containing complex binding	Birc2	IPI	RGD:621237|RGD:621313|RGD:1310457|RGD:1310158	Rat	PMID:15590916|RGD:1624191
Molecular Function	GO:0051087	protein-folding chaperone binding	BIRC2	IPI	UniProtKB:P08238	Human	PMID:18239673
Molecular Function	GO:0003713	transcription coactivator activity	BIRC2	IMP		Human	PMID:21653699
Molecular Function	GO:0016740	transferase activity	BIRC2	EXP		Human	PMID:19008929
Molecular Function	GO:0043130	ubiquitin binding	BIRC2	IDA		Human	PMID:16510124
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	BIRC2	EXP		Human	PMID:10797013
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	BIRC2	IDA		Human	PMID:11907583
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	BIRC2	IDA		Human	PMID:21931591
Molecular Function	GO:0008270	zinc ion binding	BIRC2	IDA		Human	PMID:19153467
Molecular Function	GO:0008270	zinc ion binding	BIRC2	IDA		Human	PMID:20447407
Cellular Component	GO:0035631	CD40 receptor complex	Birc2	IDA		Mouse	MGI:MGI:4462284|PMID:20614026
Cellular Component	GO:0005737	cytoplasm	BIRC2	IDA		Human	PMID:16510124
Cellular Component	GO:0005737	cytoplasm	BIRC2	IDA		Human	PMID:18239673
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	Birc2	IDA		Mouse	MGI:MGI:4462284|PMID:20614026
Cellular Component	GO:0045121	membrane raft	Birc2	IDA		Rat	PMID:15590916|RGD:1624191
Cellular Component	GO:0005634	nucleus	BIRC2	IDA		Human	PMID:15665297
Cellular Component	GO:0005634	nucleus	BIRC2	IDA		Human	PMID:16510124
Cellular Component	GO:0005634	nucleus	BIRC2	IDA		Human	PMID:18239673
Cellular Component	GO:0005634	nucleus	Birc2	IDA		Rat	PMID:16343737|RGD:1643531
Cellular Component	GO:0032991	protein-containing complex	Birc2	IDA		Rat	PMID:15590916|RGD:1624191
Cellular Component	GO:0001741	XY body	Birc2	IDA		Rat	PMID:16343737|RGD:1643531
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Birc2	IGI	MGI:MGI:1197007	Mouse	PMID:18621737
Biological Process	GO:0070266	necroptotic process	Birc2	IMP		Mouse	MGI:MGI:5315337|PMID:21052097
Biological Process	GO:0043066	negative regulation of apoptotic process	BIRC2	IDA		Human	PMID:21525013
Biological Process	GO:0060546	negative regulation of necroptotic process	Birc2	IGI	MGI:MGI:104798	Mouse	PMID:21052097
Biological Process	GO:1902443	negative regulation of ripoptosome assembly involved in necroptotic process	Birc2	IGI	MGI:MGI:104798	Mouse	PMID:21052097
Biological Process	GO:1902443	negative regulation of ripoptosome assembly involved in necroptotic process	Birc2	IGI	MGI:MGI:108212	Mouse	PMID:21052097
Biological Process	GO:0001890	placenta development	Birc2	IMP	MGI:MGI:2156197	Mouse	PMID:15640352
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	BIRC2	IEP		Human	PMID:12761501
Biological Process	GO:1902524	positive regulation of protein K48-linked ubiquitination	BIRC2	IDA		Human	PMID:21931591
Biological Process	GO:1902523	positive regulation of protein K63-linked ubiquitination	BIRC2	IDA		Human	PMID:21931591
Biological Process	GO:1902527	positive regulation of protein monoubiquitination	BIRC2	IDA		Human	PMID:21931591
Biological Process	GO:1902916	positive regulation of protein polyubiquitination	Birc2	IGI	MGI:MGI:2384911	Mouse	PMID:18621737
Biological Process	GO:1902916	positive regulation of protein polyubiquitination	Birc2	IGI	MGI:MGI:1197007	Mouse	PMID:18621737
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	BIRC2	IDA		Human	PMID:11907583
Biological Process	GO:0000209	protein polyubiquitination	BIRC2	IDA		Human	PMID:11907583
Biological Process	GO:0042981	regulation of apoptotic process	BIRC2	IMP		Human	PMID:21737330
Biological Process	GO:0051726	regulation of cell cycle	BIRC2	IDA		Human	PMID:15665297
Biological Process	GO:0060544	regulation of necroptotic process	BIRC2	IMP		Human	PMID:21737330
Biological Process	GO:1901222	regulation of NIK/NF-kappaB signaling	Birc2	IGI	MGI:MGI:1197007	Mouse	PMID:18621737
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	Birc2	IMP		Mouse	PMID:21052097
Biological Process	GO:0051591	response to cAMP	Birc2	IEP		Rat	PMID:11849428|RGD:1643533
Biological Process	GO:0045471	response to ethanol	Birc2	IEP		Rat	PMID:16687129|RGD:1643530
Biological Process	GO:0001666	response to hypoxia	Birc2	IDA		Rat	PMID:12023884|RGD:631960
Biological Process	GO:0014070	response to organic cyclic compound	Birc2	IEP		Rat	PMID:15371238|RGD:1643532
Biological Process	GO:0010243	response to organonitrogen compound	Birc2	IEP		Rat	PMID:16687129|RGD:1643530

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern