Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BIRC3
  • Mouse genes Birc3
  • Rat genes Birc3
  • Zfish genes birc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Birc3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	BIRC3	IPI	UniProtKB:Q12933	Human	PMID:11907583
Molecular Function	GO:0005515	protein binding	BIRC3	IPI	UniProtKB:Q9UDY8	Human	PMID:16123224
Molecular Function	GO:0005515	protein binding	BIRC3	IPI	UniProtKB:Q12933	Human	PMID:16282325
Molecular Function	GO:0005515	protein binding	BIRC3	IPI	UniProtKB:O95999	Human	PMID:16395405
Molecular Function	GO:0005515	protein binding	BIRC3	IPI	UniProtKB:P61088	Human	PMID:19690564
Molecular Function	GO:0005515	protein binding	BIRC3	IPI	UniProtKB:Q12933	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	BIRC3	IPI	UniProtKB:O94966	Human	PMID:21849505
Molecular Function	GO:0005515	protein binding	BIRC3	IPI	UniProtKB:O43353	Human	PMID:21931591
Molecular Function	GO:0005515	protein binding	BIRC3	IPI	UniProtKB:P57078	Human	PMID:21931591
Molecular Function	GO:0005515	protein binding	BIRC3	IPI	UniProtKB:Q13546	Human	PMID:21931591
Molecular Function	GO:0005515	protein binding	BIRC3	IPI	UniProtKB:Q9Y572	Human	PMID:21931591
Molecular Function	GO:0005515	protein binding	BIRC3	IPI	UniProtKB:Q12933	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	BIRC3	IPI	UniProtKB:P62837	Human	PMID:22902369
Molecular Function	GO:0005515	protein binding	BIRC3	IPI	UniProtKB:Q12933	Human	PMID:23524849
Molecular Function	GO:0005515	protein binding	BIRC3	IPI	UniProtKB:Q12933	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	BIRC3	IPI	UniProtKB:P61088	Human	PMID:25260751
Molecular Function	GO:0005515	protein binding	Birc3	IPI	UniProtKB:P39429	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0044877	protein-containing complex binding	Birc3	IPI	RGD:1310457|RGD:620544	Rat	PMID:12786973|RGD:2298728
Molecular Function	GO:0016740	transferase activity	BIRC3	EXP		Human	PMID:19008929
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	BIRC3	EXP		Human	PMID:10797013
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	BIRC3	IDA		Human	PMID:16395405
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	BIRC3	IDA		Human	PMID:21931591
Cellular Component	GO:0005737	cytoplasm	BIRC3	IDA		Human	PMID:15665297
Cellular Component	GO:0005737	cytoplasm	BIRC3	IDA		Human	PMID:16123224
Cellular Component	GO:0005829	cytosol	BIRC3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045121	membrane raft	Birc3	IDA		Rat	PMID:15590916|RGD:1624191
Cellular Component	GO:0005654	nucleoplasm	BIRC3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	BIRC3	IDA		Human	PMID:15665297
Cellular Component	GO:0005634	nucleus	BIRC3	IDA		Human	PMID:16123224
Cellular Component	GO:0032991	protein-containing complex	Birc3	IDA		Rat	PMID:12786973|RGD:2298728
Cellular Component	GO:0032991	protein-containing complex	Birc3	IDA		Rat	PMID:15590916|RGD:1624191
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Birc3	IGI	MGI:MGI:1197009	Mouse	PMID:18621737
Biological Process	GO:0070266	necroptotic process	Birc3	IDA		Mouse	MGI:MGI:5315337|PMID:21052097
Biological Process	GO:0060546	negative regulation of necroptotic process	Birc3	IMP		Mouse	MGI:MGI:5315337|PMID:21052097
Biological Process	GO:0042326	negative regulation of phosphorylation	Birc3	IMP		Mouse	MGI:MGI:5315337|PMID:21052097
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	Birc3	IMP		Mouse	MGI:MGI:5315337|PMID:21052097
Biological Process	GO:1902916	positive regulation of protein polyubiquitination	Birc3	IGI	MGI:MGI:1197009	Mouse	PMID:18621737
Biological Process	GO:0031398	positive regulation of protein ubiquitination	BIRC3	IDA		Human	PMID:21931591
Biological Process	GO:0042981	regulation of apoptotic process	BIRC3	IMP		Human	PMID:21737330
Biological Process	GO:0060544	regulation of necroptotic process	BIRC3	IMP		Human	PMID:21737330
Biological Process	GO:1901222	regulation of NIK/NF-kappaB signaling	Birc3	IGI	MGI:MGI:1197009	Mouse	PMID:18621737
Biological Process	GO:0007283	spermatogenesis	Birc3	IEP		Rat	PMID:16343737|RGD:1643531

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern