Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BIRC6
  • Mouse genes Birc6
  • Rat genes Birc6
  • Zfish genes birc6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Birc6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004869	cysteine-type endopeptidase inhibitor activity	BIRC6	IMP		Human	PMID:15200957
Molecular Function	GO:0005515	protein binding	BIRC6	IPI	UniProtKB:Q9H4P4	Human	PMID:14765125
Molecular Function	GO:0005515	protein binding	BIRC6	IPI	UniProtKB:O43464	Human	PMID:15200957
Molecular Function	GO:0005515	protein binding	BIRC6	IPI	UniProtKB:Q9NR28	Human	PMID:15200957
Molecular Function	GO:0005515	protein binding	BIRC6	IPI	UniProtKB:O60645	Human	PMID:18329369
Molecular Function	GO:0005515	protein binding	BIRC6	IPI	UniProtKB:P40818	Human	PMID:18329369
Molecular Function	GO:0005515	protein binding	BIRC6	IPI	UniProtKB:P53350	Human	PMID:18329369
Molecular Function	GO:0005515	protein binding	BIRC6	IPI	UniProtKB:P61006	Human	PMID:18329369
Molecular Function	GO:0005515	protein binding	BIRC6	IPI	UniProtKB:P62491	Human	PMID:18329369
Molecular Function	GO:0005515	protein binding	BIRC6	IPI	UniProtKB:Q02241	Human	PMID:18329369
Molecular Function	GO:0005515	protein binding	BIRC6	IPI	UniProtKB:Q02750	Human	PMID:18329369
Molecular Function	GO:0005515	protein binding	BIRC6	IPI	UniProtKB:Q96A65	Human	PMID:18329369
Molecular Function	GO:0005515	protein binding	BIRC6	IPI	UniProtKB:P53350	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	Birc6	IPI	UniProtKB:Q9H4P4	Mouse	MGI:MGI:3054509|PMID:15314180
Molecular Function	GO:0061631	ubiquitin conjugating enzyme activity	Birc6	IDA		Mouse	PMID:9628897
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	BIRC6	IDA		Human	PMID:15200957
Cellular Component	GO:0005768	endosome	BIRC6	IDA		Human	PMID:18329369
Cellular Component	GO:0016020	membrane	BIRC6	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Birc6	IDA		Mouse	PMID:9628897
Cellular Component	GO:0005815	microtubule organizing center	BIRC6	IDA		Human	PMID:18329369
Cellular Component	GO:0030496	midbody	BIRC6	IDA		Human	PMID:18329369
Cellular Component	GO:0000922	spindle pole	BIRC6	IDA		Human	PMID:18329369
Cellular Component	GO:0005802	trans-Golgi network	BIRC6	IDA		Human	PMID:18329369
Biological Process	GO:0008283	cell population proliferation	Birc6	IMP	MGI:MGI:2678436	Mouse	PMID:15887267
Biological Process	GO:0060711	labyrinthine layer development	Birc6	IMP	MGI:MGI:3512417	Mouse	PMID:15485903
Biological Process	GO:0043066	negative regulation of apoptotic process	BIRC6	IMP		Human	PMID:15200957
Biological Process	GO:0043066	negative regulation of apoptotic process	Birc6	IMP	MGI:MGI:3573859	Mouse	PMID:15300255
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	BIRC6	IMP		Human	PMID:14765125
Biological Process	GO:0001890	placenta development	Birc6	IMP		Mouse	MGI:MGI:3511408|PMID:15485903
Biological Process	GO:0008284	positive regulation of cell population proliferation	Birc6	IMP	MGI:MGI:2678436	Mouse	PMID:15887267
Biological Process	GO:0042127	regulation of cell population proliferation	Birc6	IMP	MGI:MGI:3512417	Mouse	PMID:15485903
Biological Process	GO:0032465	regulation of cytokinesis	BIRC6	IMP		Human	PMID:18329369
Biological Process	GO:0060712	spongiotrophoblast layer development	Birc6	IMP	MGI:MGI:3512417	Mouse	PMID:15485903

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern